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Author Details

Mark Noble
University of Rochester Medical Center
1981
139
55
PMIDPaper TitleJournal TitlePublished Year
33368893Erythropoietin promotes functional recovery in a mouse model of postoperative ileus.Neurogastroenterol Motil2021
31608497Peripheral nerve injury and myelination: Potential therapeutic strategies.J Neurosci Res2020
32924936The many roles of C1q.Elife2020
309014244-Aminopyridine as a Single Agent Diagnostic and Treatment for Severe Nerve Crush Injury.Mil Med2019
310939824-Aminopyridine attenuates muscle atrophy after sciatic nerve crush injury in mice.Muscle Nerve2019
29623914Heterozygous carriers of galactocerebrosidase mutations that cause Krabbe disease have impaired microglial function and defective repair of myelin damage.Neural Regen Res2018
28575206Heterozygote galactocerebrosidase (GALC) mutants have reduced remyelination and impaired myelin debris clearance following demyelinating injury.Hum Mol Genet2017
28168703Erythropoietin accelerates functional recovery after moderate sciatic nerve crush injury.Muscle Nerve2017
278611254-Aminopyridine promotes functional recovery and remyelination in acute peripheral nerve injury.EMBO Mol Med2016
26469940Mutation of ataxia-telangiectasia mutated is associated with dysfunctional glutathione homeostasis in cerebellar astroglia.Glia2016
27593486Erythropoietin Enhanced Recovery After Traumatic Nerve Injury: Myelination and Localized Effects.J Hand Surg Am2016
27977664Lysosomal Re-acidification Prevents Lysosphingolipid-Induced Lysosomal Impairment and Cellular Toxicity.PLoS Biol2016
25481740Redox biology in normal cells and cancer: restoring function of the redox/Fyn/c-Cbl pathway in cancer cells offers new approaches to cancer treatment.Free Radic Biol Med2015
26310626A novel mouse model for ataxia-telangiectasia with a N-terminal mutation displays a behavioral defect and a low incidence of lymphoma but no increased oxidative burden.Hum Mol Genet2015
25633192cFLIP is critical for oligodendrocyte protection from inflammation.Cell Death Differ2015
24477866Delayed transplantation of precursor cell-derived astrocytes provides multiple benefits in a rat model of Parkinsons.EMBO Mol Med2014
24458840Cool-1-mediated inhibition of c-Cbl modulates multiple critical properties of glioblastomas, including the ability to generate tumors in vivo.Stem Cells2014
23642358iOPs: a new tool for studying myelin pathologies?Cell Stem Cell2013
24133281Oligodendrocyte/type-2 astrocyte progenitor cells and glial-restricted precursor cells generate different tumor phenotypes in response to the identical oncogenes.J Neurosci2013
24048837MEK1/2 inhibition suppresses tamoxifen toxicity on CNS glial progenitor cells.J Neurosci2013
23606532Inhibition of redox/Fyn/c-Cbl pathway function by Cdc42 controls tumour initiation capacity and tamoxifen sensitivity in basal-like breast cancer cells.EMBO Mol Med2013
20732974A composite likelihood approach to the analysis of longitudinal clonal data on multitype cellular systems under an age-dependent branching process.Biostatistics2011
22027545Cell therapies for the central nervous system: how do we identify the best candidates?Curr Opin Neurol2011
21918888Precursor cell biology and the development of astrocyte transplantation therapies: lessons from spinal cord injury.Neurotherapeutics2011
21407803Transplantation of specific human astrocytes promotes functional recovery after spinal cord injury.PLoS One2011
21040723Glial restricted precursor cell transplant with cyclic adenosine monophosphate improved some autonomic functions but resulted in a reduced graft size after spinal cord contusion injury in rats.Exp Neurol2011
21211773Oxidative-reductionist approaches to stem and progenitor cell function.Cell Stem Cell2011
19508238Saddlepoint approximations to the moments of multitype age-dependent branching processes, with applications.Biometrics2010
21056994Mathematical and experimental approaches to identify and predict the effects of chemotherapy on neuroglial precursors.Cancer Res2010
19064774Novel multi-modal strategies to promote brain and spinal cord injury recovery.Stroke2009
18430259Systemic 5-fluorouracil treatment causes a syndrome of delayed myelin destruction in the central nervous system.J Biol2008
18803859Transplanted astrocytes derived from BMP- or CNTF-treated glial-restricted precursors have opposite effects on recovery and allodynia after spinal cord injury.J Biol2008
17298174Chemically diverse toxicants converge on Fyn and c-Cbl to disrupt precursor cell function.PLoS Biol2007
16643674Astrocytes derived from glial-restricted precursors promote spinal cord repair.J Biol2006
16990388Cancer stem cells.N Engl J Med2006
17125495CNS progenitor cells and oligodendrocytes are targets of chemotherapeutic agents in vitro and in vivo.J Biol2006
16707014Stochastic modeling of oligodendrocyte generation in cell culture: model validation with time-lapse data.Theor Biol Med Model2006
16472202Implications for CNS repair of redox modulation of cell survival, division and differentiation.Curr Alzheimer Res2006
15737094A stochastic model to analyze clonal data on multi-type cell populations.Biometrics2005
17142878Ethics in the trenches: a multifaceted analysis of the stem cell debate.Stem Cell Rev2005
16356108Redox regulation of precursor cell function: insights and paradoxes.Antioxid Redox Signal2005
15723074EIF2B5 mutations compromise GFAP+ astrocyte generation in vanishing white matter leukodystrophy.Nat Med2005
15748733Estimating the life-span of oligodendrocytes from clonal data on their development in cell culture.Math Biosci2005
14675726The possible role of myelin destruction as a precipitating event in Alzheimer's disease.Neurobiol Aging2004
15530870Acute transplantation of glial-restricted precursor cells into spinal cord contusion injuries: survival, differentiation, and effects on lesion environment and axonal regeneration.Exp Neurol2004
14697351Getting a GR(i)P on oligodendrocyte development.Dev Biol2004
15036880The complex identity of brain tumors: emerging concerns regarding origin, diversity and plasticity.Trends Neurosci2004
12846992Redox state as a central modulator of precursor cell function.Ann N Y Acad Sci2003
12966219The cortical ancestry of oligodendrocytes: common principles and novel features.Dev Neurosci2003
14637087Directed nerve outgrowth is enhanced by engineered glial substrates.Exp Neurol2003
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Collaborators

University of Rochester
Co-authored papers 47
Netherlands Institute for Brain Research
Co-authored papers 13
Frimley Health NHS Foundation Trust
Co-authored papers 9
American Association for Cancer Research, Henry Ford Hospital, Ludwig Institute for Cancer Research, National Cancer Institute, Salk Institute for Biological Studies, University of Cambridge, University of Texas MD Anderson Cancer Center, Virginia Commonwealth University
Co-authored papers 8
University of Glasgow, University Place
Co-authored papers 7
Baylor College of Medicine
Co-authored papers 7
UCL Institute of Prion Diseases
Co-authored papers 5
The Ludwig Institute for Cancer Research
Co-authored papers 4
University of Rochester Medical Center, Wilmot Cancer Institute
Co-authored papers 4
Marine Biological Laboratory
Co-authored papers 3
University of Colorado School of Medicine
Co-authored papers 3
Molecular and Clinical Sciences Research Institute, University of London
Co-authored papers 3
3Weill Institute for Neurosciences, University of California san francisco
Co-authored papers 2
3Weill Institute for Neurosciences, University of California san francisco
Co-authored papers 2
Co-authored papers 2
IRCCS Casa Sollievo della Sofferenza, University of Milano-Bicocca
Co-authored papers 1
Harvard Medical School
Co-authored papers 1
Cancer Research Center (CSIC/USAL/IBSAL)
Co-authored papers 1
Co-authored papers 1
Institute of Stem Cells and Regenerative Medicine (inStem)
Co-authored papers 1
Salk Institute for Biological Studies
Co-authored papers 1
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Novartis Pharma AG
Co-authored papers 1
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University of California, University of California Irvine
Co-authored papers 1
National Human Genome Research Institute, National Institutes of Health
Co-authored papers 1