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Author Details

Nikolaus Grigorieff
RNA Therapeutics Institute, University of Massachusetts Chan Medical School
1995
118
62
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37216561Quantification of gallium cryo-FIB milling damage in biological lamellae.Proc Natl Acad Sci U S A2023
38010355Baited reconstruction with 2D template matching for high-resolution structure determination in vitro and in vivo without template bias.Elife2023
37613706Exploring the Limits of 2D Template Matching for Detecting Targets in Cellular Cryo-EM Images.Microsc Microanal2023
36949197From primordial clocks to circadian oscillators.Nature2023
36005291In situ single particle classification reveals distinct 60S maturation intermediates in cells.Elife2022
36382886Defocus Corrected Large Area Cryo-EM (DeCo-LACE) for label-free detection of molecules across entire cell sections.Elife2022
34114559Locating macromolecular assemblies in cells by 2D template matching with cisTEM.Elife2021
34804546Cryo-TEM simulations of amorphous radiation-sensitive samples using multislice wave propagation.IUCrJ2021
32427100mRNA stem-loops can pause the ribosome by hindering A-site tRNA binding.Elife2020
31988524Structure and assembly of calcium homeostasis modulator proteins.Nat Struct Mol Biol2020
32066965Publisher Correction: Structure and assembly of calcium homeostasis modulator proteins.Nat Struct Mol Biol2020
31914397Structure of the Vesicular Stomatitis Virus L Protein in Complex with Its Phosphoprotein Cofactor.Cell Rep2020
31768058In situ structure determination at nanometer resolution using TYGRESS.Nat Methods2020
30528101Analysis of discrete local variability and structural covariance in macromolecular assemblies using Cryo-EM and focused classification.Ultramicroscopy2019
31182604High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations.Proc Natl Acad Sci U S A2019
31233764In situ Structure of Rotavirus VP1 RNA-Dependent RNA Polymerase.J Mol Biol2019
30846696Cryo-EM fibril structures from systemic AA amyloidosis reveal the species complementarity of pathological amyloids.Nat Commun2019
29453354Physical basis of amyloid fibril polymorphism.Nat Commun2018
30139843Severing enzymes amplify microtubule arrays through lattice GTP-tubulin incorporation.Science2018
29754826Atomic Resolution Cryo-EM Structure of β-Galactosidase.Structure2018
29513216<i>cis</i>TEM, user-friendly software for single-particle image processing.Elife2018
29656875Structural Mechanism of Functional Modulation by Gene Splicing in NMDA Receptors.Neuron2018
28692650Expression, purification, and contaminant detection for structural studies of Ralstonia metallidurance ClC protein rm1.PLoS One2017
28300532Mechanism of ribosome rescue by ArfA and RF2.Elife2017
28250125Conformational States of a Soluble, Uncleaved HIV-1 Envelope Trimer.J Virol2017
28467302Single-protein detection in crowded molecular environments in cryo-EM images.Elife2017
29027901Structure of RNA polymerase bound to ribosomal 30S subunit.Elife2017
28538735Ensemble cryo-EM elucidates the mechanism of translation fidelity.Nature2017
28506635CryoEM Structure of an Influenza Virus Receptor-Binding Site Antibody-Antigen Interface.J Mol Biol2017
27434674Ribosomeâ¿¢RelA structures reveal the mechanism of stringent response activation.Elife2016
27935481Structure of the transporter associated with antigen processing trapped by herpes simplex virus.Elife2016
27223329Structure of a Holliday junction complex reveals mechanisms governing a highly regulated DNA transaction.Elife2016
27135925Activation of NMDA receptors and the mechanism of inhibition by ifenprodil.Nature2016
27572728Frealign: An Exploratory Tool for Single-Particle Cryo-EM.Methods Enzymol2016
27185936Cryo-EM reveals the steric zipper structure of a light chain-derived amyloid fibril.Proc Natl Acad Sci U S A2016
27159452Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome.Elife2016
26023829Measuring the optimal exposure for single particle cryo-EM using a 2.6 ÿ reconstruction of rotavirus VP6.Elife2015
26439008Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM.Elife2015
26278980CTFFIND4: Fast and accurate defocus estimation from electron micrographs.J Struct Biol2015
26278979Automatic estimation and correction of anisotropic magnification distortion in electron microscopes.J Struct Biol2015
26351699Peptide dimer structure in an Aβ(1-42) fibril visualized with cryo-EM.Proc Natl Acad Sci U S A2015
26318383Evaluation of super-resolution performance of the K2 electron-counting camera using 2D crystals of aquaporin-0.J Struct Biol2015
26144317Structure of the L Protein of Vesicular Stomatitis Virus from Electron Cryomicroscopy.Cell2015
25910204A primer to single-particle cryo-electron microscopy.Cell2015
24657230Frealix: model-based refinement of helical filament structures from electron micrographs.J Struct Biol2014
25043550Structures of yeast 80S ribosome-tRNA complexes in the rotated and nonrotated conformations.Structure2014
24927574Taura syndrome virus IRES initiates translation by binding its tRNA-mRNA-like structural element in the ribosomal decoding center.Proc Natl Acad Sci U S A2014
24906155Molecular basis for age-dependent microtubule acetylation by tubulin acetyltransferase.Cell2014
23089332Location of the dsRNA-dependent polymerase, VP1, in rotavirus particles.J Mol Biol2013
24324137Structure of the ribosome with elongation factor G trapped in the pretranslocation state.Proc Natl Acad Sci U S A2013
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Collaborators

RNA Therapeutics Institute, University of Massachusetts Chan Medical School
Co-authored papers 9
University of California san francisco
Co-authored papers 9
Quantitative Bioscience Institute, University of California san francisco
Co-authored papers 7
Columbia University
Co-authored papers 4
Medical Research Council
Co-authored papers 4
Howard Hughes Medical Institute
Co-authored papers 4
Co-authored papers 3
Lawrence Berkeley National Laboratory
Co-authored papers 2
The Francis Crick Institute
Co-authored papers 2
Co-authored papers 2
The University of Texas, McGovern Medical School
Co-authored papers 2
University of Missouri
Co-authored papers 1
Old Dominion University
Co-authored papers 1
Co-authored papers 1
Ecole Polytechnique Federale de Lausanne (EPFL), University of Lausanne
Co-authored papers 1
National Institutes of Health
Co-authored papers 1
University of California, USA Quantitative Biosciences Institute (QBI) san francisco
Co-authored papers 1
Zernike Institute for Advanced Materials, University of Groningen
Co-authored papers 1
Baylor College of Medicine
Co-authored papers 1
Co-authored papers 1
McGovern Medical School at the University of Texas Health Science Center
Co-authored papers 1
University of Virginia
Co-authored papers 1
Beth Israel Deaconess Medical Center RN380F
Co-authored papers 1
Fred Hutchinson Cancer Center
Co-authored papers 1
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 1
The State University of New Jersey
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Institute of Science and Technology Austria (ISTA)
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Purdue University
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The University of Sydney
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Harvard Medical School
Co-authored papers 1