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Author Details

David J Orlicky
University of Colorado School of Medicine
1978
206
43
PMIDPaper TitleJournal TitlePublished Year
36394352Expression and T cell regulatory action of the PD-1 immune checkpoint in the ovary and fallopian tube.Am J Reprod Immunol2023
37548929REMOTE BURN INJURY IN AGED MICE INDUCES COLONIC LYMPHOID AGGREGATE EXPANSION AND DYSBIOSIS OF THE FECAL MICROBIOME WHICH CORRELATES WITH NEUROINFLAMMATION.Shock2023
37892451Endogenous Fructose Production and Metabolism Drive Metabolic Dysregulation and Liver Disease in Mice with Hereditary Fructose Intolerance.Nutrients2023
37647292Expression of circadian regulatory genes is dysregulated by increased cytokine production in mice subjected to concomitant intestinal injury and parenteral nutrition.PLoS One2023
37574341Ethanol exacerbates pulmonary complications after burn injury in mice, regardless of frequency of ethanol exposures.Burns2023
36946778Innate Immune Zonation in the Liver: NF-κB (p50) Activation and C-Reactive Protein Expression in Response to Endotoxemia Are Zone Specific.J Immunol2023
37277650Triplication of the interferon receptor locus contributes to hallmarks of Down syndrome in a mouse model.Nat Genet2023
37238651High Fructose Corn Syrup Accelerates Kidney Disease and Mortality in Obese Mice with Metabolic Syndrome.Biomolecules2023
37173326Pharmacologic inhibition of HNF4α prevents parenteral nutrition associated cholestasis in mice.Sci Rep2023
37468479Publisher Correction: Pharmacologic inhibition of HNF4α prevents parenteral nutrition associated cholestasis in mice.Sci Rep2023
37398356Endocrine pancreas-specific <i>Gclc</i> gene deletion causes a severe diabetes phenotype.bioRxiv2023
37471421IL-6 mediates the hepatic acute phase response after prerenal azotemia in a clinically defined murine model.Am J Physiol Renal Physiol2023
37430099Estrogen and Androgen Receptor Status in Uterosacral Ligaments of Women with Pelvic Organ Prolapse Stratified by the Pelvic Organ Prolapse Histology Quantification System.Reprod Sci2023
36994079Phosphate depletion in insulin-insensitive skeletal muscle drives AMPD activation and sarcopenia in chronic kidney disease.iScience2023
36847440Adrenal gene expression dynamics support hibernation in 13-lined ground squirrels.Physiol Genomics2023
36633484Thioredoxin reductase 1 regulates hepatic inflammation and macrophage activation during acute cholestatic liver injury.Hepatol Commun2023
36150611Profiling the oxylipidome in aged mice after chronic ethanol feeding: Identifying lipid metabolites as drivers of hepatocyte stress.Alcohol2023
34387888Pharmacologic activation of hepatic farnesoid X receptor prevents parenteral nutrition-associated cholestasis in mice.Hepatology2022
37483863Oxidative stress, glutathione, and CYP2E1 in 1,4-dioxane liver cytotoxicity and genotoxicity: insights from animal models.Curr Opin Environ Sci Health2022
35603143Ethanol Intoxication Impairs Respiratory Function and Bacterial Clearance and Is Associated With Neutrophil Accumulation in the Lung After <i>Streptococcus pneumoniae</i> Infection.Front Immunol2022
35429548Liver metabolomics identifies bile acid profile changes at early stages of alcoholic liver disease in mice.Chem Biol Interact2022
35635324Inhaled silica nanoparticles cause chronic kidney disease in rats.Am J Physiol Renal Physiol2022
35365681Dietary fat promotes antibiotic-induced Clostridioides difficile mortality in mice.NPJ Biofilms Microbiomes2022
35392033Age-Related Intestinal Dysbiosis and Enrichment of Gut-specific Bacteria in the Lung Are Associated With Increased Susceptibility to <i>Streptococcus pneumoniae</i> Infection in Mice.Front Aging2022
36426684Absence of IκBβ/NFκB signaling does not attenuate acetaminophen-induced hepatic injury.Anat Rec (Hoboken)2022
36338478Oxidized low density lipoprotein in the liver causes decreased permeability of liver lymphatic- but not liver sinusoidal-endothelial cells <i>via</i> VEGFR-3 regulation of VE-Cadherin.Front Physiol2022
36209823The role of FXR and TGR5 in reversing and preventing progression of Western diet-induced hepatic steatosis, inflammation, and fibrosis in mice.J Biol Chem2022
36378690The autophagic protein p62 is a target of reactive aldehydes in human and murine cholestatic liver disease.PLoS One2022
36158190Perilipin-2 promotes lipid droplet-plasma membrane interactions that facilitate apocrine lipid secretion in secretory epithelial cells of the mouse mammary gland.Front Cell Dev Biol2022
34916594Disruption of monocyte-macrophage differentiation and trafficking by a heme analog during active inflammation.Mucosal Immunol2022
35184170Chemopreventive efficacy of silibinin against basal cell carcinoma growth and progression in UVB-irradiated Ptch+/- mice.Carcinogenesis2022
35123994Oxidative stress induces inflammation of lens cells and triggers immune surveillance of ocular tissues.Chem Biol Interact2022
34923085Proteomic analysis of alcohol-associated hepatitis reveals glycoprotein NMB (GPNMB) as a novel hepatic and serum biomarker.Alcohol2022
34641722Lenvatinib Plus Anti-PD-1 Combination Therapy for Advanced Cancers: Defining Mechanisms of Resistance in an Inducible Transgenic Model of Thyroid Cancer.Thyroid2022
34811964Lipidomics and Redox Lipidomics Indicate Early Stage Alcohol-Induced Liver Damage.Hepatol Commun2022
34726736APAP-Induced IκBβ/NFκB Signaling Drives Hepatic Il6 Expression and Associated Sinusoidal Dilation.Toxicol Sci2022
34600989Oxidative stress and genotoxicity in 1,4-dioxane liver toxicity as evidenced in a mouse model of glutathione deficiency.Sci Total Environ2022
32961356Oxidized Low-Density Lipoprotein Drives Dysfunction of the Liver Lymphatic System.Cell Mol Gastroenterol Hepatol2021
33759579The developing murine lung is susceptible to acetaminophen toxicity.Am J Physiol Lung Cell Mol Physiol2021
33673577Supplemental Ascorbate Diminishes DNA Damage Yet Depletes Glutathione and Increases Acute Liver Failure in a Mouse Model of Hepatic Antioxidant System Disruption.Antioxidants (Basel)2021
33693819Identification of Dose-Dependent DNA Damage and Repair Responses From Subchronic Exposure to 1,4-Dioxane in Mice Using a Systems Analysis Approach.Toxicol Sci2021
34674721Correction to: A novel murine model of multi-day moderate ethanol exposure reveals increased intestinal dysfunction and liver inflammation with age.Immun Ageing2021
34556145A novel murine model of multi-day moderate ethanol exposure reveals increased intestinal dysfunction and liver inflammation with age.Immun Ageing2021
34585971Pulmonary implications of acetaminophen exposures independent of hepatic toxicity.Am J Physiol Lung Cell Mol Physiol2021
34552272Umami-induced obesity and metabolic syndrome is mediated by nucleotide degradation and uric acid generation.Nat Metab2021
34575033Titration of Androgen Signaling: How Basic Studies Have Informed Clinical Trials Using High-Dose Testosterone Therapy in Castrate-Resistant Prostate Cancer.Life (Basel)2021
34425299Impaired GSH biosynthesis disrupts eye development, lens morphogenesis and PAX6 function.Ocul Surf2021
34774795miR-199a-5p inhibits the expression of ABCB11 in obstructive cholestasis.J Biol Chem2021
34206909Histopathological Analysis of Adrenal Glands after Simian Varicella Virus Infection.Viruses2021
34310734NF-κB Regulation of LRH-1 and ABCG5/8 Potentiates Phytosterol Role in the Pathogenesis of Parenteral Nutrition-Associated Cholestasis.Hepatology2021
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Collaborators

Colin T Shearn
University of Colorado School of Medicine
Co-authored papers 30
Ronald J Sokol
Digestive Health Institute, Children's Hospital Colorado
Co-authored papers 9
Michael W Devereaux
University of Colorado School of Medicine
Co-authored papers 8
Clyde J Wright
University of Colorado School of Medicine and Children's Hospital Colorado
Co-authored papers 6
Aimee L Anderson
University of Colorado School of Medicine
Co-authored papers 6
Kenneth J Hurt
Co-authored papers 4
Karim C El Kasmi
Boehringer Ingelheim Pharma GmbH & Co. KG
Co-authored papers 4
Angelo D'Alessandro
University of Colorado Anschutz Medical Campus
Co-authored papers 4
Swati Ghosh
University of Colorado School of Medicine
Co-authored papers 4
Frank J Gonzalez
Co-authored papers 3
Marshall Scott Lucia
University of Colorado School of Medicine
Co-authored papers 3
Julie A Reisz
University of Colorado Anschutz Medical Campus
Co-authored papers 3
Jeffrey B Kopp
National Institutes of Health, National Institute of Diabetes
Co-authored papers 2
Caroline H Johnson
Yale School of Public Health
Co-authored papers 2
Wells A Messersmith
University of Colorado Anschutz Medical Campus
Co-authored papers 2
Daniel W Nebert
Co-authored papers 2
Samuel W French
Co-authored papers 2
Matthew D Hirschey
Duke Molecular Physiology Institute, Duke University School of Medicine
Co-authored papers 2
Adrie van Bokhoven
University of Colorado Anschutz Medical Campus
Co-authored papers 2
Dana A Hill
Co-authored papers 1
James DeGregori
University of Colorado Anschutz Medical Campus
Co-authored papers 1
Sarah Gehrke
University of Colorado Anschutz Medical Campus
Co-authored papers 1
Joshua D Rabinowitz
Lewis Sigler Institute for Integrative Genomics, Princeton University
Co-authored papers 1
Thomas E Morrison
University of Colorado Anschutz Medical Campus
Co-authored papers 1
Aik Choon Tan
Huntsman Cancer Institute, The University of Utah
Co-authored papers 1
Michael P Kavanaugh
University of Montana.
Co-authored papers 1
Nicholas O Davidson
Co-authored papers 1
James M Sikela
University of Colorado
Co-authored papers 1
Anis Karimpour-Fard
University of Colorado
Co-authored papers 1
Bennett Davenport
Co-authored papers 1
Release 1.2