Author details

Full Name

Jane Worthington

Affiliation

ORCID

Career Start Year

1987

Papers

279

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
33542305	Associations between human leukocyte antigens and renal function.	Scientific Reports	2021
32985786	Human leukocyte antigen associations with renal function among ethnic minorities in the United Kingdom.	HLA	2020
30789234	Association of TNFSF4 (OX40L) polymorphisms with systemic sclerosis-related calcinosis.	Rheumatology	2019
31672989	GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways.	Nat Commun	2019
30573655	Genome-wide meta-analysis reveals shared new <i>loci</i> in systemic seropositive rheumatic diseases.	Ann Rheum Dis	2019
31092410	Chromatin interactions reveal novel gene targets for drug repositioning in rheumatic diseases.	Annals of the Rheumatic Diseases	2019
31123311	Author Correction: Genotypic variability-based genome-wide association study identifies non-additive loci HLA-C and IL12B for psoriasis.	Journal of Human Genetics	2019
29259305	Genotypic variability-based genome-wide association study identifies non-additive loci HLA-C and IL12B for psoriasis.	Journal of Human Genetics	2018
30224649	Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes.	Nat Genet	2018
30176915	Increased DNA methylation variability in rheumatoid arthritis-discordant monozygotic twins.	Genome Med	2018
27574969	A synonymous variant in TREX1 is associated with systemic sclerosis and severe digital ischaemia.	Scandinavian Journal of Rheumatology	2017
28668810	An MIF Promoter Polymorphism Is Associated with Susceptibility to Pulmonary Arterial Hypertension in Diffuse Cutaneous Systemic Sclerosis.	J Rheumatol	2017
28706201	Genotypic variability based association identifies novel non-additive loci DHCR7 and IRF4 in sero-negative rheumatoid arthritis.	Scientific Reports	2017
28569263	The genetics revolution in rheumatology: large scale genomic arrays and genetic mapping.	Nature reviews. Rheumatology	2017
27193031	A combined large-scale meta-analysis identifies COG6 as a novel shared risk locus for rheumatoid arthritis and systemic lupus erythematosus.	Annals of the Rheumatic Diseases	2017
25239882	The genetics of rheumatoid arthritis: risk and protection in different stages of the evolution of RA.	Rheumatology	2016
27111665	Brief Report: IRF4 Newly Identified as a Common Susceptibility Locus for Systemic Sclerosis and Rheumatoid Arthritis in a Cross-Disease Meta-Analysis of Genome-Wide Association Studies.	Arthritis Rheumatol	2016
27109064	Major histocompatibility complex harbors widespread genotypic variability of non-additive risk of rheumatoid arthritis including epistasis.	Scientific Reports	2016
26879349	Immunochip Analyses of Epistasis in Rheumatoid Arthritis Confirm Multiple Interactions within MHC and Suggest Novel Non-MHC Epistatic Signals.	Journal of Rheumatology	2016
27182969	A method to decipher pleiotropy by detecting underlying heterogeneity driven by hidden subgroups applied to autoimmune and neuropsychiatric diseases.	Nat Genet	2016
26830904	Association of Toll-like receptor 4 (TLR4) with chronic plaque type psoriasis and psoriatic arthritis.	Archives of Dermatological Research	2016
27267163	Genetic susceptibility to rheumatoid arthritis and its implications for novel drug discovery.	Expert Opinion on Drug Discovery	2016
26895230	Replication of Associations of Genetic Loci Outside the HLA Region With Susceptibility to Anti-Cyclic Citrullinated Peptide-Negative Rheumatoid Arthritis.	Arthritis and Rheumatology	2016
26814849	Differential Methylation as a Biomarker of Response to Etanercept in Patients With Rheumatoid Arthritis.	Arthritis and Rheumatology	2016
26386125	Loci associated with N-glycosylation of human IgG are not associated with rheumatoid arthritis: a Mendelian randomisation study.	Ann Rheum Dis	2016
26338038	Influence of TYK2 in systemic sclerosis susceptibility: a new locus in the IL-12 pathway.	Ann Rheum Dis	2016
26690697	Cryopreservation of cells does not substantially alter the DNA methylome of CD3+CD4+ T cells.	Scandinavian Journal of Rheumatology	2016
27861577	Identifying Causal Genes at the Multiple Sclerosis Associated Region 6q23 Using Capture Hi-C.	PLoS ONE	2016
27799070	Capture Hi-C identifies a novel causal gene, IL20RA, in the pan-autoimmune genetic susceptibility region 6q23.		2016
24532676	High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci.	Ann Rheum Dis	2015
25919528	Association of HLA-DRB1 haplotypes with rheumatoid arthritis severity, mortality, and treatment response.	JAMA	2015
25817017	A large-scale genetic analysis reveals a strong contribution of the HLA class II region to giant cell arteritis susceptibility.	Am J Hum Genet	2015
25849893	TYK2 protein-coding variants protect against rheumatoid arthritis and autoimmunity, with no evidence of major pleiotropic effects on non-autoimmune complex traits.	PLoS One	2015
26314374	Confirmation of CCR6 as a risk factor for anti-topoisomerase I antibodies in systemic sclerosis.	Clin Exp Rheumatol	2015
26053495	Statistical colocalization of genetic risk variants for related autoimmune diseases in the context of common controls.	Nature Genetics	2015
26220137	Corrigendum: Statistical colocalization of genetic risk variants for related autoimmune diseases in the context of common controls.	Nature Genetics	2015
26509058	Genetics of RA susceptibility, what comes next?	RMD Open	2015
26258845	Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases.	Nat Genet	2015
26286434	New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis.	Int J Epidemiol	2015
26616563	Capture Hi-C reveals novel candidate genes and complex long-range interactions with related autoimmune risk loci.	Nature Communications	2015
24442880	Leri's pleonosteosis, a congenital rheumatic disease, results from microduplication at 8q22.1 encompassing GDF6 and SDC2 and provides insight into systemic sclerosis pathogenesis.	Ann Rheum Dis	2015
24092415	A weighted genetic risk score using all known susceptibility variants to estimate rheumatoid arthritis risk.	Ann Rheum Dis	2015
24656864	Fine mapping seronegative and seropositive rheumatoid arthritis to shared and distinct HLA alleles by adjusting for the effects of heterogeneity.	Am J Hum Genet	2014
25453756	A role for noncoding variation in schizophrenia.	Cell Rep	2014
25526303	Take your PICS: moving from GWAS to immune function.	Immunity	2014
24449572	Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study.	Arthritis and Rheumatology	2014
24401602	A genome-wide association study follow-up suggests a possible role for PPARG in systemic sclerosis susceptibility.	Arthritis Res Ther	2014
24390342	Genetics of rheumatoid arthritis contributes to biology and drug discovery.	Nature	2014
24387989	Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis.	Am J Hum Genet	2014
25199642	Identification of IL12RB1 as a novel systemic sclerosis susceptibility locus.	Arthritis Rheumatol	2014