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Author Details

Alexander Krasnitz
Simons Center for Quantitative Biology
1988
64
27
PMIDPaper TitleJournal TitlePublished Year
36351074Genetic Ancestry Inference from Cancer-Derived Molecular Data across Genomic and Transcriptomic Platforms.Cancer Res2023
36594871Correction: Genetic Ancestry Inference from Cancer-Derived Molecular Data across Genomic and Transcriptomic Platforms.Cancer Res2023
35978189Ordered and deterministic cancer genome evolution after p53 loss.Nature2022
32401198Novel insights into breast cancer copy number genetic heterogeneity revealed by single-cell genome sequencing.Elife2020
32083660Multiplex accurate sensitive quantitation (MASQ) with application to minimal residual disease in acute myeloid leukemia.Nucleic Acids Res2020
31727682Copolymerization of single-cell nucleic acids into balls of acrylamide gel.Genome Res2020
32633781SOAT1 promotes mevalonate pathway dependency in pancreatic cancer.J Exp Med2020
32703770Intraductal Transplantation Models of Human Pancreatic Ductal Adenocarcinoma Reveal Progressive Transition of Molecular Subtypes.Cancer Discov2020
32432904Integrated Computational Pipeline for Single-Cell Genomic Profiling.JCO Clin Cancer Inform2020
30378070CORE: A Software Tool for Delineating Regions of Recurrent DNA Copy Number Alteration in Cancer.Methods Mol Biol2019
31433971The Immune Landscape of Cancer.Immunity2019
30378078Statistically Supported Identification of Tumor Subtypes.Methods Mol Biol2019
29180472Utility of Single-Cell Genomics in Diagnostic Evaluation of Prostate Cancer.Cancer Res2018
29853643Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer.Cancer Discov2018
29625051Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation.Cell2018
28587830Early Detection of Cancer in Blood Using Single-Cell Analysis: A Proposal.Trends Mol Med2017
28989791Sweepstake evolution revealed by population-genetic analysis of copy-number alterations in single genomes of breast cancer.R Soc Open Sci2017
27681436Mammary Tumor-Associated RNAs Impact Tumor Cell Proliferation, Invasion, and Migration.Cell Rep2016
25858951Optimizing sparse sequencing of single cells for highly multiplex copy number profiling.Genome Res2015
25030933Computational methods for DNA copy-number analysis of tumors.Methods Mol Biol2014
25409689Significant distinct branches of hierarchical trees: a framework for statistical analysis and applications to biological data.BMC Genomics2014
23744040Target inference from collections of genomic intervals.Proc Natl Acad Sci U S A2013
23805207Two Distinct Categories of Focal Deletions in Cancer Genomes.PLoS One2013
22566646A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions.Proc Natl Acad Sci U S A2012
22722845A tumour suppressor network relying on the polyamine-hypusine axis.Nature2012
22750847DDX5 regulates DNA replication and is required for cell proliferation in a subset of breast cancer cells.Cancer Discov2012
21399628Tumour evolution inferred by single-cell sequencing.Nature2011
19903760Inferring tumor progression from genomic heterogeneity.Genome Res2010
20829823Towards patient-based cancer therapeutics.Nat Biotechnol2010
20592421Genomic architecture characterizes tumor progression paths and fate in breast cancer patients.Sci Transl Med2010
20434983A RSC/nucleosome complex determines chromatin architecture and facilitates activator binding.Cell2010
18922857Novel genomic alterations and clonal evolution in chronic lymphocytic leukemia revealed by representational oligonucleotide microarray analysis (ROMA).Blood2009
19800577Functional identification of tumor-suppressor genes through an in vivo RNA interference screen in a mouse lymphoma model.Cancer Cell2009
18519636DLC1 is a chromosome 8p tumor suppressor whose loss promotes hepatocellular carcinoma.Genes Dev2008
18719096Brk is coamplified with ErbB2 to promote proliferation in breast cancer.Proc Natl Acad Sci U S A2008
19012953An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer.Cell2008
17363630Strong association of de novo copy number mutations with autism.Science2007
17925434Oncogenic cooperation and coamplification of developmental transcription factor genes in lung cancer.Proc Natl Acad Sci U S A2007
17912030Copy-number variants in patients with a strong family history of pancreatic cancer.Cancer Biol Ther2007
17142309Novel patterns of genome rearrangement and their association with survival in breast cancer.Genome Res2006
16869738High-resolution ROMA CGH and FISH analysis of aneuploid and diploid breast tumors.Cold Spring Harb Symp Quant Biol2005
11690405Coherent gluon production in very-high-energy heavy-ion collisions.Phys Rev Lett2001
11290231Initial gluon multiplicity in heavy-ion collisions.Phys Rev Lett2001
10990673Initial energy density of gluons produced in very-high-energy nuclear collisionsPhys Rev Lett2000
10016929Effects of spatial size, lattice doubling, and source operators on the hadron spectrum with dynamical staggered quarks at 6/g2=5.6.Phys Rev D Part Fields1994
10017646Chern-Simons number diffusion in (1+1)-dimensional Higgs theory.Phys Rev D Part Fields1994
10017350Hadron spectrum and matrix elements in QCD with dynamical Wilson fermions at 6/g2=5.3.Phys Rev D Part Fields1994
10016931Baryon density correlations in high temperature hadronic matter.Phys Rev D Part Fields1994
10015982Thermodynamics of lattice QCD with two light quarks on a 16(3) x 8 lattice.Phys Rev D Part Fields1993
10016722Finite-size and quark mass effects on the QCD spectrum with two flavors.Phys Rev D Part Fields1993
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Collaborators

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Co-authored papers 15
Bharathidasan University, Indian Institute of Science
Co-authored papers 6
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Institute for Cancer Research, Oslo University Hospital
Co-authored papers 3
2Ontario Institute for Cancer Research
Co-authored papers 3
University of California San Diego
Co-authored papers 2
The University of Texas MD Anderson Cancer Center
Co-authored papers 2
Institute of Molecular Medicine, Feinstein Institutes for Medical Research
Co-authored papers 2
Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine
Co-authored papers 2
Sandra and Edward Meyer Cancer Center
Co-authored papers 2
Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto
Co-authored papers 2
Harvard Medical School
Co-authored papers 2
Stanley Institute for Cognitive Genomics
Co-authored papers 2
Ontario Institute for Cancer Research
Co-authored papers 2
Stanford Center for Biomedical Informatics Research, Stanford University
Co-authored papers 2
Henry Ford Hospital
Co-authored papers 2
Columbia University
Co-authored papers 2
Co-authored papers 2
School of Pharmaceutical Sciences of Ribeirao Preto, University of Sao Paulo
Co-authored papers 2
The University of Texas MD Anderson Cancer Center
Co-authored papers 2
Princess Maxima Center for Pediatric Oncology
Co-authored papers 1
Rhode Island Hospital
Co-authored papers 1
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Lineberger Cancer Center, University of North Carolina
Co-authored papers 1
Vingroup Big Data Institute
Co-authored papers 1
MS Research Unit
Co-authored papers 1
Broad Institute of MIT and Harvard, USA Dana-Farber Cancer Institute
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Stanford University
Co-authored papers 1