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Author Details

Srinivasan Yegnasubramanian
Johns Hopkins University School of Medicine
1999
161
58
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37907729Prognostic and therapeutic potential of senescent stromal fibroblasts in prostate cancer.Nat Rev Urol2024
36309102Genomic Characterization of Prostatic Basal Cell Carcinoma.Am J Pathol2023
37808834Somatic mutations reveal hyperactive Notch signaling and racial disparities in prurigo nodularis.medRxiv2023
37713507Lung tumor-infiltrating T<sub>reg</sub> have divergent transcriptional profiles and function linked to checkpoint blockade response.Sci Immunol2023
37905029Convergent alterations in the tumor microenvironment of MYC-driven human and murine prostate cancer.bioRxiv2023
38063199CD4 T cell-activating neoantigens enhance personalized cancer vaccine efficacy.JCI Insight2023
37971875MYC-driven increases in mitochondrial DNA copy number occur early and persist throughout prostatic cancer progression.JCI Insight2023
37674985Intravenous BCG vaccination reduces SARS-CoV-2 severity and promotes extensive reprogramming of lung immune cells.iScience2023
37347938Progressive Spreading of DNA Methylation in the GSTP1 Promoter CpG Island across Transitions from Precursors to Invasive Prostate Cancer.Cancer Prev Res (Phila)2023
37345219DNA methyltransferase inhibitor exposure-response: Challenges and opportunities.Clin Transl Sci2023
37116491Systematic elucidation and pharmacological targeting of tumor-infiltrating regulatory T cell master regulators.Cancer Cell2023
37180140Corrigendum: Convergent antibody responses are associated with broad neutralization of hepatitis C virus.Front Immunol2023
37040583Precision Oncology Core Data Model to Support Clinical Genomics Decision Making.JCO Clin Cancer Inform2023
37034584Distinct Myeloid Derived Suppressor Cell Populations Promote Tumor Aggression in Glioblastoma.bioRxiv2023
36519323CCRL2 affects the sensitivity of myelodysplastic syndrome and secondary acute myeloid leukemia cells to azacitidine.Haematologica2023
36736631Radiotherapy Deserts: The Impact of Race, Poverty, and the Rural-Urban Continuum on Density of Providers and the Use of Radiation Therapy in the US.Int J Radiat Oncol Biol Phys2023
36865273MYC-driven increases in mitochondrial DNA copy number occur early and persist throughout prostatic cancer progression.bioRxiv2023
36373171Single-cell atlas of epithelial and stromal cell heterogeneity by lobe and strain in the mouse prostate.Prostate2023
35104804Health inequity drives disease biology to create disparities in prostate cancer outcomes.J Clin Invest2022
35349483IgM anti-ACE2 autoantibodies in severe COVID-19 activate complement and perturb vascular endothelial function.JCI Insight2022
35452513Identifying Phased Mutations and Complex Rearrangements in Human Prostate Cancer Cell Lines through Linked-Read Whole-Genome Sequencing.Mol Cancer Res2022
36521928Preconditioning of the immune system modulates the response of papillary thyroid cancer to immune checkpoint inhibitors.J Immunother Cancer2022
36411491De novo methylation of histone H3K23 by the methyltransferases EHMT1/GLP and EHMT2/G9a.Epigenetics Chromatin2022
36194476Androgen receptor activity in prostate cancer dictates efficacy of bipolar androgen therapy through MYC.J Clin Invest2022
34861998Mechanisms, Challenges, and Opportunities in Combined Radiation and Hormonal Therapies.Semin Radiat Oncol2022
35188986Multiplex immunohistochemical phenotyping of T cells in primary prostate cancer.Prostate2022
35313583Dynamic single-cell RNA sequencing reveals BCG vaccination curtails SARS-CoV-2 induced disease severity and lung inflammation.bioRxiv2022
35201318Entinostat Decreases Immune Suppression to Promote Antitumor Responses in a HER2+ Breast Tumor Microenvironment.Cancer Immunol Res2022
33328650Genomic and phenotypic heterogeneity in prostate cancer.Nat Rev Urol2021
33576154Epigenetic and transcriptional analysis reveals a core transcriptional program conserved in clonal prostate cancer metastases.Mol Oncol2021
33724955Resistance to androgen receptor signaling inhibition does not necessitate development of neuroendocrine prostate cancer.JCI Insight2021
33691089Metabolic programs define dysfunctional immune responses in severe COVID-19 patients.Cell Rep2021
33830946Functional characterization of CD4+ T cell receptors crossreactive for SARS-CoV-2 and endemic coronaviruses.J Clin Invest2021
34431104Reciprocal YAP1 loss and INSM1 expression in neuroendocrine prostate cancer.J Pathol2021
34608287Author Correction: Transcriptional programs of neoantigen-specific TIL in anti-PD-1-treated lung cancers.Nature2021
34402095Phenotypic characterization of two novel cell line models of castration-resistant prostate cancer.Prostate2021
34290408Transcriptional programs of neoantigen-specific TIL in anti-PD-1-treated lung cancers.Nature2021
34032307Longitudinal measurement of subcutaneous and intratibial human prostate cancer xenograft growth and response to ionizing radiation by plasma Alu and LINE-1 ctDNA: A comparison to standard methods.Prostate2021
33955569Genomic profiles and clinical outcomes in primary versus secondary metastatic hormone-sensitive prostate cancer.Prostate2021
34191807GSTP1 positive prostatic adenocarcinomas are more common in Black than White men in the United States.PLoS One2021
32468444Pervasive promoter hypermethylation of silenced TERT alleles in human cancers.Cell Oncol (Dordr)2020
32015231A conserved intratumoral regulatory T cell signature identifies 4-1BB as a pan-cancer target.J Clin Invest2020
32935120Metabolic programs define dysfunctional immune responses in severe COVID-19 patients.medRxiv2020
33015525Dickkopf-1 Can Lead to Immune Evasion in Metastatic Castration-Resistant Prostate Cancer.JCO Precis Oncol2020
32694696Correction: Integrated single-cell and bulk gene expression and ATAC-seq reveals heterogeneity and early changes in pathways associated with resistance to cetuximab in HNSCC-sensitive cell lines.Br J Cancer2020
32362655Integrated single-cell and bulk gene expression and ATAC-seq reveals heterogeneity and early changes in pathways associated with resistance to cetuximab in HNSCC-sensitive cell lines.Br J Cancer2020
32304697An in Situ Atlas of Mitochondrial DNA in Mammalian Tissues Reveals High Content in Stem and Proliferative Compartments.Am J Pathol2020
29673712Update on Systemic Prostate Cancer Therapies: Management of Metastatic Castration-resistant Prostate Cancer in the Era of Precision Oncology.Eur Urol2019
31653272Immunogenicity of prostate cancer is augmented by BET bromodomain inhibition.J Immunother Cancer2019
30082453Molecular Pathology of High-Grade Prostatic Intraepithelial Neoplasia: Challenges and Opportunities.Cold Spring Harb Perspect Med2019
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Mark C Markowski
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
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Chi V Dang
Johns Hopkins University School of Medicine
Co-authored papers 4
Alan W Partin
The Brady Urological Institute, Johns Hopkins University School of Medicine
Co-authored papers 4
Kenneth W Kinzler
Co-authored papers 4
Michael J Considine
Johns Hopkins University School of Medicine
Co-authored papers 4
Lauren M Sauer
University of California los angeles
Co-authored papers 3
Brian W Simons
Center for Comparative Medicine, Baylor College of Medicine
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Alexander V Favorov
Johns Hopkins School of Medicine
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Akihiro Sakai
Tokai University
Co-authored papers 3
Theresa Guo
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Release 1.2