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Author Details

John Connelly
Institute of Genetics and Cancer, University of Edinburgh
2000
14
10
PMIDPaper TitleJournal TitlePublished Year
36351380Toll-like receptor 2 orchestrates a tumor suppressor response in non-small cell lung cancer.Cell Rep2022
36351380Toll-like receptor 2 orchestrates a tumor suppressor response in non-small cell lung cancer.Cell Rep2022
34676045ATR inhibition reverses the resistance of homologous recombination deficient MGMT<sup>low</sup>/MMR<sup>proficient</sup> cancer cells to temozolomide.Oncotarget2021
34676045ATR inhibition reverses the resistance of homologous recombination deficient MGMT<sup>low</sup>/MMR<sup>proficient</sup> cancer cells to temozolomide.Oncotarget2021
32586373Epigenome-wide DNA methylation analysis of small cell lung cancer cell lines suggests potential chemotherapy targets.Clin Epigenetics2020
32586373Epigenome-wide DNA methylation analysis of small cell lung cancer cell lines suggests potential chemotherapy targets.Clin Epigenetics2020
31102023Exposure time versus cytotoxicity for anticancer agents.Cancer Chemother Pharmacol2019
31102023Exposure time versus cytotoxicity for anticancer agents.Cancer Chemother Pharmacol2019
29196464Deconstruction of a Metastatic Tumor Microenvironment Reveals a Common Matrix Response in Human Cancers.Cancer Discov2018
30355619The NCI Transcriptional Pharmacodynamics Workbench: A Tool to Examine Dynamic Expression Profiling of Therapeutic Response in the NCI-60 Cell Line Panel.Cancer Res2018
29196464Deconstruction of a Metastatic Tumor Microenvironment Reveals a Common Matrix Response in Human Cancers.Cancer Discov2018
30355619The NCI Transcriptional Pharmacodynamics Workbench: A Tool to Examine Dynamic Expression Profiling of Therapeutic Response in the NCI-60 Cell Line Panel.Cancer Res2018
27247353Small Cell Lung Cancer Screen of Oncology Drugs, Investigational Agents, and Gene and microRNA Expression.J Natl Cancer Inst2016
27247353Small Cell Lung Cancer Screen of Oncology Drugs, Investigational Agents, and Gene and microRNA Expression.J Natl Cancer Inst2016
27265504CXCR2 Inhibition Profoundly Suppresses Metastases and Augments Immunotherapy in Pancreatic Ductal Adenocarcinoma.Cancer Cell2016
27265504CXCR2 Inhibition Profoundly Suppresses Metastases and Augments Immunotherapy in Pancreatic Ductal Adenocarcinoma.Cancer Cell2016
26351324Sarcoma Cell Line Screen of Oncology Drugs and Investigational Agents Identifies Patterns Associated with Gene and microRNA Expression.Mol Cancer Ther2015
26351324Sarcoma Cell Line Screen of Oncology Drugs and Investigational Agents Identifies Patterns Associated with Gene and microRNA Expression.Mol Cancer Ther2015
21765476CHEK2 genomic and proteomic analyses reveal genetic inactivation or endogenous activation across the 60 cell lines of the US National Cancer Institute.Oncogene2012
21765476CHEK2 genomic and proteomic analyses reveal genetic inactivation or endogenous activation across the 60 cell lines of the US National Cancer Institute.Oncogene2012
19741151Cellular inhibition of checkpoint kinase 2 (Chk2) and potentiation of camptothecins and radiation by the novel Chk2 inhibitor PV1019 [7-nitro-1H-indole-2-carboxylic acid {4-[1-(guanidinohydrazone)-ethyl]-phenyl}-amide].J Pharmacol Exp Ther2009
19741151Cellular inhibition of checkpoint kinase 2 (Chk2) and potentiation of camptothecins and radiation by the novel Chk2 inhibitor PV1019 [7-nitro-1H-indole-2-carboxylic acid {4-[1-(guanidinohydrazone)-ethyl]-phenyl}-amide].J Pharmacol Exp Ther2009
16332985Differential gene expression as a potential classifier of 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole-sensitive and -insensitive cell lines.Mol Pharmacol2006
16332985Differential gene expression as a potential classifier of 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole-sensitive and -insensitive cell lines.Mol Pharmacol2006
12606787Genotoxic profiling of MCF-7 breast cancer cell line elucidates gene expression modifications underlying toxicity of the anticancer drug 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole.Mol Pharmacol2003
12606787Genotoxic profiling of MCF-7 breast cancer cell line elucidates gene expression modifications underlying toxicity of the anticancer drug 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole.Mol Pharmacol2003
10857990UCN-01 enhances the in vitro toxicity of clinical agents in human tumor cell lines.Invest New Drugs2000
10857990UCN-01 enhances the in vitro toxicity of clinical agents in human tumor cell lines.Invest New Drugs2000
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Collaborators

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Co-authored papers 4
Mayo Clinic
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Co-authored papers 3
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Co-authored papers 3
University of Genoa and Ospedale Policlinico San Martino
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Co-authored papers 2
National Cancer Institute
Co-authored papers 2
Center for Cancer Research, National Cancer Institute
Co-authored papers 2
National Cancer Institute
Co-authored papers 2
Illumina Inc.
Co-authored papers 1
Institute of Genetics and Cancer, University of Edinburgh
Co-authored papers 1
National Cancer Institute
Co-authored papers 1
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UNC School of Medicine, The University of North Carolina at Chapel Hill
Co-authored papers 1
Johns Hopkins School of Medicine, National Cancer Institute, Princeton University, University of Colorado Anschutz Medical Campus, University of Pittsburgh, University of Washington
Co-authored papers 1
Gustave Roussy Cancer Center, INSERM U1170
Co-authored papers 1
The University of North Carolina School of Medicine
Co-authored papers 1
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CRUK Cambridge Institute, University of Cambridge
Co-authored papers 1
Leidos Biomedical Research Inc.
Co-authored papers 1
Center for Cancer Research, National Cancer Institute
Co-authored papers 1
and Blood Institute, National Institutes of Health
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