Author details

Full Name

Kenneth D Bromberg

Affiliation

ORCID

Career Start Year

2001

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
35902886	Distinct modulation of IFNÎ³-induced transcription by BET bromodomain and catalytic P300/CBP inhibition in breast cancer.	Clin Epigenetics	2022
34055218	Discovery of a Potent and Selective Covalent p300/CBP Inhibitor.	ACS Medicinal Chemistry Letters	2021
34019788	Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.	Mol Cell	2021
33631370	Discovery of spirohydantoins as selective, orally bioavailable inhibitors of p300/CBP histone acetyltransferases.	Bioorg Med Chem Lett	2021
31926787	Corrigendum to "Investigation of biaryl heterocycles as inhibitors of Wee1 kinase" [Bioorg. Med. Chem. Lett. 29 (2019) 1481-1486].	Bioorganic and Medicinal Chemistry Letters	2020
29769713	Author Correction: Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours.	Nature	2018
29804834	Time-Resolved Analysis Reveals Rapid Dynamics and Broad Scope of the CBP/p300 Acetylome.	Cell	2018
28114273	The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity.	Nat Chem Biol	2017
28953875	Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours.	Nature	2017
29348807	Discovery of Spiro Oxazolidinediones as Selective, Orally Bioavailable Inhibitors of p300/CBP Histone Acetyltransferases.	ACS Med Chem Lett	2017
25589931	Pyrimidine-based tricyclic molecules as potent and orally efficacious inhibitors of wee1 kinase.	ACS Medicinal Chemistry Letters	2015
19861414	Cannabinoid 1 receptor and interleukin-6 receptor together induce integration of protein kinase and transcription factor signaling to trigger neurite outgrowth.	J Biol Chem	2010
18487186	Design logic of a cannabinoid receptor signaling network that triggers neurite outgrowth.	Science	2008
18508528	Regulation of neurite outgrowth by G(i/o) signaling pathways.	Front Biosci	2008
18270596	The ER-bound RING finger protein 5 (RNF5/RMA1) causes degenerative myopathy in transgenic mice and is deregulated in inclusion body myositis.	PLoS One	2008
17804730	Increased expression of the E3 ubiquitin ligase RNF5 is associated with decreased survival in breast cancer.	Cancer Res	2007
16166642	JAMP, a Jun N-terminal kinase 1 (JNK1)-associated membrane protein, regulates duration of JNK activity.	Mol Cell Biol	2005
15182198	1,4-Benzoquinone is a topoisomerase II poison.	Biochemistry	2004
15491148	DNA ligation catalyzed by human topoisomerase II alpha.	Biochemistry	2004
12653542	Quinolone action against human topoisomerase IIalpha: stimulation of enzyme-mediated double-stranded DNA cleavage.	Biochemistry	2003
12473657	A two-drug model for etoposide action against human topoisomerase IIalpha.	Journal of Biological Chemistry	2003
12050172	Human topoisomerase IIalpha possesses an intrinsic nucleic acid specificity for DNA ligation. Use of 5' covalently activated oligonucleotide substrates to study enzyme mechanism.	Journal of Biological Chemistry	2002
11444988	DNA cleavage and religation by human topoisomerase II alpha at high temperature.	Biochemistry	2001