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Author Details

Brent A Orr
St. Jude Children's Research Hospital
2000
122
40
Antoine Forget (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37503880High-grade glioma in infants and young children is histologically, molecularly, and clinically diverse: Results from the SJYC07 trial and institutional experience.Neuro Oncol2024
37197736Diffuse leptomeningeal glioneuronal tumor in a child masquerading as an intramedullary spinal pilocytic astrocytoma.Neurooncol Adv2023
37522896DNA-methylation subgroups carry no prognostic significance in ATRT-SHH patients in clinical trial cohorts.Acta Neuropathol2023
35652336Phase II study of alisertib as a single agent for treating recurrent or progressive atypical teratoid/rhabdoid tumor.Neuro Oncol2023
37215955Predicting methylation class from diffusely infiltrating adult gliomas using multimodality MRI data.Neurooncol Adv2023
34009420Pre-operative embolization for staged treatment of infantile choroid plexus papilloma.Childs Nerv Syst2022
35676649Comprehensive study of semi-supervised learning for DNA methylation-based supervised classification of central nervous system tumors.BMC Bioinformatics2022
35798383Primary cilia control translation and the cell cycle in medulloblastoma.Genes Dev2022
35642016Convergent evolution and multi-wave clonal invasion in H3 K27-altered diffuse midline gliomas treated with a PDGFR inhibitor.Acta Neuropathol Commun2022
35483358The myogenesis program drives clonal selection and drug resistance in rhabdomyosarcoma.Dev Cell2022
35967099Sustained and durable response with Alisertib monotherapy in the treatment of relapsed Atypical Teratoid Rhabdoid Tumor (ATRT).Neurooncol Adv2022
36131015Unified rhombic lip origins of group 3 and group 4 medulloblastoma.Nature2022
35982322Molecular classification and outcome of children with rare CNS embryonal tumors: results from St. Jude Children's Research Hospital including the multi-center SJYC07 and SJMB03 clinical trials.Acta Neuropathol2022
34894262Revised clinical and molecular risk strata define the incidence and pattern of failure in medulloblastoma following risk-adapted radiotherapy and dose-intensive chemotherapy: results from a phase III multi-institutional study.Neuro Oncol2022
32619305Biology and grading of pleomorphic xanthoastrocytoma-what have we learned about it?Brain Pathol2021
33827698Molecular classification of a complex structural rearrangement of the RB1 locus in an infant with sporadic, isolated, intracranial, sellar region retinoblastoma.Acta Neuropathol Commun2021
33737307Relevance of Molecular Groups in Children with Newly Diagnosed Atypical Teratoid Rhabdoid Tumor: Results from Prospective St. Jude Multi-institutional Trials.Clin Cancer Res2021
33502920Clinical Outcomes and Patient-Matched Molecular Composition of Relapsed Medulloblastoma.J Clin Oncol2021
34407349Lorlatinib in a Child with <i>ALK</i>-Fusion-Positive High-Grade Glioma.N Engl J Med2021
34782706Methylation profiling reveals novel molecular classes of rhabdomyosarcoma.Sci Rep2021
34545084Comprehensive molecular characterization of pediatric radiation-induced high-grade glioma.Nat Commun2021
34678152Serial assessment of measurable residual disease in medulloblastoma liquid biopsies.Cancer Cell2021
34301788Genomes for Kids: The Scope of Pathogenic Mutations in Pediatric Cancer Revealed by Comprehensive DNA and RNA Sequencing.Cancer Discov2021
34215733Patient-derived models recapitulate heterogeneity of molecular signatures and drug response in pediatric high-grade glioma.Nat Commun2021
34315877Retinoblastoma from human stem cell-derived retinal organoids.Nat Commun2021
34145313SMARCB1 deletion in atypical teratoid rhabdoid tumors results in human endogenous retrovirus K (HML-2) expression.Sci Rep2021
33405951Outcomes by Clinical and Molecular Features in Children With Medulloblastoma Treated With Risk-Adapted Therapy: Results of an International Phase III Trial (SJMB03).J Clin Oncol2021
33074854YAP1-FAM118B Fusion Defines a Rare Subset of Childhood and Young Adulthood Meningiomas.Am J Surg Pathol2021
30499906Anaplastic Astrocytoma in a Child With Coffin-Siris Syndrome and a Germline SMARCE1 Mutation: A Case Report.J Pediatr Hematol Oncol2020
33506206Outcome and molecular analysis of young children with choroid plexus carcinoma treated with non-myeloablative therapy: results from the SJYC07 trial.Neurooncol Adv2020
31929384Oncogenic GOPC-ROS1 Fusion Identified in a Congenital Glioblastoma Case.J Pediatr Hematol Oncol2020
31865440Correction to: Risk-adapted therapy and biological heterogeneity in pineoblastoma: integrated clinico-pathological analysis from the prospective, multi-center SJMB03 and SJYC07 trials.Acta Neuropathol2020
32017698<i>TSC2</i> alterations in anaplastic ependymoma progression to ependymosarcoma.Clin Neuropathol2020
31802236Risk-adapted therapy and biological heterogeneity in pineoblastoma: integrated clinico-pathological analysis from the prospective, multi-center SJMB03 and SJYC07 trials.Acta Neuropathol2020
31949013<i>De novo</i> primary central nervous system pure erythroid leukemia/sarcoma with t(1;16)(p31;q24) <i>NFIA/CBFA2T3</i> translocation.Haematologica2020
31948942An ABC Transporter Drives Medulloblastoma Pathogenesis by Regulating Sonic Hedgehog Signaling.Cancer Res2020
31768671Molecular subgrouping of primary pineal parenchymal tumors reveals distinct subtypes correlated with clinical parameters and genetic alterations.Acta Neuropathol2020
31850678Treatment of pediatric high-grade central nervous system tumors with high-dose methotrexate in combination with multiagent chemotherapy: A single-institution experience.Pediatr Blood Cancer2020
32772175WNT-activated embryonal tumors of the pineal region: ectopic medulloblastomas or a novel pineoblastoma subgroup?Acta Neuropathol2020
32307792cIMPACT-NOW update 6: new entity and diagnostic principle recommendations of the cIMPACT-Utrecht meeting on future CNS tumor classification and grading.Brain Pathol2020
32303840Pediatric bithalamic gliomas have a distinct epigenetic signature and frequent EGFR exon 20 insertions resulting in potential sensitivity to targeted kinase inhibition.Acta Neuropathol2020
32239782Pathology, diagnostics, and classification of medulloblastoma.Brain Pathol2020
32519082Patient-derived orthotopic xenografts of pediatric brain tumors: a St. Jude resource.Acta Neuropathol2020
32296180Germline Elongator mutations in Sonic Hedgehog medulloblastoma.Nature2020
31468188An update on the central nervous system manifestations of Li-Fraumeni syndrome.Acta Neuropathol2020
30639498H3 K27M Mutations in Thalamic Pilocytic Astrocytomas with Anaplasia.World Neurosurg2019
31802000The molecular landscape of ETMR at diagnosis and relapse.Nature2019
32923859DNA Methylation Profiling Reveals Prognostically Significant Groups in Pediatric Adrenocortical Tumors: A Report From the International Pediatric Adrenocortical Tumor Registry.JCO Precis Oncol2019
30192422Alternative lengthening of telomeres, ATRX loss and H3-K27M mutations in histologically defined pilocytic astrocytoma with anaplasia.Brain Pathol2019
31300448Unbiased Metabolic Profiling Predicts Sensitivity of High MYC-Expressing Atypical Teratoid/Rhabdoid Tumors to Glutamine Inhibition with 6-Diazo-5-Oxo-L-Norleucine.Clin Cancer Res2019
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Collaborators

St. Jude Children's Research Hospital
Co-authored papers 32
St. Jude Children's Research Hospital
Co-authored papers 30
St. Jude Children's Research Hospital
Co-authored papers 26
Wilmer Eye Institute, Johns Hopkins Medical Institutions
Co-authored papers 20
St Jude Children's Research Hospital
Co-authored papers 20
Co-authored papers 16
University of Texas Southwestern Medical School
Co-authored papers 10
University of California Los Angeles
Co-authored papers 9
Stanford University
Co-authored papers 9
Rady Children's Hospital San Diego.
Co-authored papers 9
Texas Children's Cancer Center, Baylor College of Medicine
Co-authored papers 9
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 9
Cancer Research UK Cambridge Institute, University of Cambridge
Co-authored papers 8
St. Jude Children's Research Hospital
Co-authored papers 8
Children's Hospitals and Clinics of Minnesota
Co-authored papers 8
The Hospital for Sick Children
Co-authored papers 8
St. Jude Children's Research Hospital
Co-authored papers 8
St. Jude Children's Research Hospital
Co-authored papers 8
Hopp Children's Cancer Center (KiTZ)
Co-authored papers 8
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 7
Co-authored papers 7
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 7
St Jude Children's Research Hospital
Co-authored papers 7
Co-authored papers 6
Co-authored papers 6
Co-authored papers 6
German Cancer Research Center (DKFZ)
Co-authored papers 6
German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK)
Co-authored papers 6
N.N. Burdenko Neurosurgical Institute
Co-authored papers 5
Stanford University
Co-authored papers 5