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Author Details

Erika Brunet
INSERM UMR 3, Imagine Institute
2002
32
21
Nathan Sheffield (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35000057Identification of Germline Non-coding Deletions in XIAP Gene Causing XIAP Deficiency Reveals a Key Promoter Sequence.J Clin Immunol2022
35246138De novo generation of the NPM-ALK fusion recapitulates the pleiotropic phenotypes of ALK+ ALCL pathogenesis and reveals the ROR2 receptor as target for tumor cells.Mol Cancer2022
34341072Unraveling Ewing Sarcoma Tumorigenesis Originating from Patient-Derived Mesenchymal Stem Cells.Cancer Res2021
33930311STAG2 mutations alter CTCF-anchored loop extrusion, reduce cis-regulatory interactions and EWSR1-FLI1 activity in Ewing sarcoma.Cancer Cell2021
34747369From circRNAs to fusion circRNAs in hematological malignancies.JCI Insight2021
33067475Repair of G1 induced DNA double-strand breaks in S-G2/M by alternative NHEJ.Nat Commun2020
31421907STAG Mutations in Cancer.Trends Cancer2019
31662298Ontogenic Changes in Hematopoietic Hierarchy Determine Pediatric Specificity and Disease Phenotype in Fusion Oncogene-Driven Myeloid Leukemia.Cancer Discov2019
29474559Genomic Alterations and Complex Subclonal Architecture in Sporadic GH-Secreting Pituitary Adenomas.J Clin Endocrinol Metab2018
30240643Chromosomal Translocation Formation Is Sufficient to Produce Fusion Circular RNAs Specific to Patient Tumor Cells.iScience2018
29956288Induction of Chromosomal Translocations with CRISPR-Cas9 and Other Nucleases: Understanding the Repair Mechanisms That Give Rise to Translocations.Adv Exp Med Biol2018
28325870CRISPR-Cas9-guided oncogenic chromosomal translocations with conditional fusion protein expression in human mesenchymal cells.Proc Natl Acad Sci U S A2017
28111015Single-Molecule Analysis of mtDNA Replication Uncovers the Basis of the Common Deletion.Mol Cell2017
26802024The second European interdisciplinary Ewing sarcoma research summit--A joint effort to deconstructing the multiple layers of a complex disease.Oncotarget2016
26443217TALEN-Induced Translocations in Human Cells.Methods Mol Biol2016
25398344Creating cancer translocations in human cells using Cas9 DSBs and nCas9 paired nicks.Methods Enzymol2014
25201414Chromosomal translocations in human cells are generated by canonical nonhomologous end-joining.Mol Cell2014
23568838Cancer translocations in human cells induced by zinc finger and TALE nucleases.Genome Res2013
21423196Homology-directed Fanconi anemia pathway cross-link repair is dependent on DNA replication.Nat Struct Mol Biol2011
21660700Homologous recombination assay for interstrand cross-link repair.Methods Mol Biol2011
21655080DNA ligase III promotes alternative nonhomologous end-joining during chromosomal translocation formation.PLoS Genet2011
21390132Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair.Nature2011
20160072Retraction for Cannata et al., Triplex-forming oligonucleotide-orthophenanthroline conjugates for efficient targeted genome modification.Proc Natl Acad Sci U S A2010
19549848Chromosomal translocations induced at specified loci in human stem cells.Proc Natl Acad Sci U S A2009
18647997Induction of chromosomal translocations in mouse and human cells using site-specific endonucleases.J Natl Cancer Inst Monogr2008
18599454Triplex-forming oligonucleotide-orthophenanthroline conjugates for efficient targeted genome modification.Proc Natl Acad Sci U S A2008
17643113Formation of NHEJ-derived reciprocal chromosomal translocations does not require Ku70.Nat Cell Biol2007
16951289Targeting chromosomal sites with locked nucleic acid-modified triplex-forming oligonucleotides: study of efficiency dependence on DNA nuclear environment.Nucleic Acids Res2006
15760901Exploring cellular activity of locked nucleic acid-modified triplex-forming oligonucleotides and defining its molecular basis.J Biol Chem2005
16049028Intercalator conjugates of pyrimidine locked nucleic acid-modified triplex-forming oligonucleotides: improving DNA binding properties and reaching cellular activities.Nucleic Acids Res2005
15560096Binding properties of the conjugates of oligo(2'-O-methylribonucleotides) with minor groove binders targeted to double stranded DNA.Nucleosides Nucleotides Nucleic Acids2004
11972355A novel strategy for the functional cloning of enzymes using filamentous phage display: the case of nucleotidyl transferases.Nucleic Acids Res2002
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Collaborators

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The University of Texas Health Science Center at San Antonio
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Technische Universitat Munchen
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Pediatric Cancer Center Barcelona, Hospital Sant Joan de Deu
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St. Anna Children's Cancer Research Institute (CCRI), Medical University of Vienna
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IRCCS Istituto Ortopedico Rizzoli
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University Hospital Erlangen
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