Author details

Full Name

Vilmantas Giedraitis

Affiliation

ORCID

Career Start Year

1996

Papers

109

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37195665	Genetic Associations Between Modifiable Risk Factors and Alzheimer Disease.	JAMA Netw Open	2023
37660032	Prediction of conversion to dementia disorders based on timed up and go dual-task test verbal and motor outcomes: a five-year prospective memory-clinic-based study.		2023
37919655	Correction: Prediction of conversion to dementia disorders based on timed up and go dual-task test verbal and motor outcomes: a five-year prospective memory-clinic-based study.		2023
37643212	Multiancestry analysis of the HLA locus in Alzheimer's and Parkinson's diseases uncovers a shared adaptive immune response mediated by <i>HLA-DRB1*04</i> subtypes.	Proc Natl Acad Sci U S A	2023
37034649	Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications.	medRxiv	2023
37019438	Dual-Task Interference of Gait Parameters During Different Conditions of the Timed Up-and-Go Test Performed by Community-Dwelling Older Adults.		2023
35120450	Mutation analysis of disease causing genes in patients with early onset or familial forms of Alzheimer's disease and frontotemporal dementia.	BMC Genomics	2022
36314207	Mixed Pathologies in a Subject with a Novel PSEN1 G206R Mutation.	Journal of Alzheimer's Disease	2022
35697829	Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals.	Commun Biol	2022
35505961	CRISPR-Cas9 treatment partially restores amyloid-Î² 42/40 in human fibroblasts with the Alzheimer's disease <i>PSEN</i> <i>1</i> M146L mutation.	Mol Ther Nucleic Acids	2022
35639372	Association of Rare APOE Missense Variants V236E and R251G With Risk of Alzheimer Disease.	JAMA Neurol	2022
35379992	New insights into the genetic etiology of Alzheimer's disease and related dementias.	Nat Genet	2022
35551307	Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.	Nat Genet	2022
35358828	Corrigendum to "Extraction of gait parameters from marker-free video recordings of timed up-and-go tests: Validity, inter- and intra-rater reliability" [Gait Posture 90 (2021) 489-495].		2022
34480422	The genomics of heart failure: design and rationale of the HERMES consortium.	ESC Heart Fail	2021
34272869	Timed "Up & Go" Dual-Task Tests: Age- and Sex-Specific Reference Values and Test-Retest Reliability in Cognitively Healthy Controls.	Physical Therapy	2021
33837451	Immune cells lacking Y chromosome show dysregulation of autosomal gene expression.	Cell Mol Life Sci	2021
33558525	Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.	Nat Commun	2021
33814444	Different Inflammatory Signatures in Alzheimer's Disease and Frontotemporal Dementia Cerebrospinal Fluid.	Journal of Alzheimer's Disease	2021
33402679	Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.	Nat Commun	2021
34628196	Extraction of gait parameters from marker-free video recordings of Timed Up-and-Go tests: Validity, inter- and intra-rater reliability.		2021
34380771	The <i>Uppsala APP</i> deletion causes early onset autosomal dominant Alzheimer's disease by altering APP processing and increasing amyloid Î² fibril formation.	Sci Transl Med	2021
32727472	Dual-task tests discriminate between dementia, mild cognitive impairment, subjective cognitive impairment, and healthy controls - a cross-sectional cohort study.	BMC Geriatrics	2020
32439900	Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction.	Nat Commun	2020
32150995	Timed Up-and-Go Dual-Task Testing in the Assessment of Cognitive Function: A Mixed Methods Observational Study for Development of the UDDGait Protocol.	International Journal of Environmental Research and Public Health	2020
31654039	Longitudinal changes in the frequency of mosaic chromosome Y loss in peripheral blood cells of aging men varies profoundly between individuals.	European Journal of Human Genetics	2020
33153203	Dual-Task Tests Predict Conversion to Dementia-A Prospective Memory-Clinic-Based Cohort Study.	International Journal of Environmental Research and Public Health	2020
32702535	The association between plasma proteomics and incident cardiovascular disease identifies MMP-12 as a promising cardiovascular risk marker in patients with chronic kidney disease.	Atherosclerosis	2020
33067605	Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals.	Nat Metab	2020
31148414	The metabolites urobilin and sphingomyelin (30:1) are associated with incident heart failure in the general population.	ESC Heart Fail	2019
30604766	Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies.	Nat Commun	2019
30374072	Mosaic loss of chromosome Y in leukocytes matters.	Nature Genetics	2019
30618330	Rationale for a Swedish cohort consortium.	Ups J Med Sci	2019
30614806	Improved Differential Diagnosis of Alzheimer's Disease by Integrating ELISA and Mass Spectrometry-Based Cerebrospinal Fluid Biomarkers.	J Alzheimers Dis	2019
30820047	Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates AÎ², tau, immunity and lipid processing.	Nat Genet	2019
31160809	Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.	Nat Genet	2019
31363756	Risk factors for subarachnoid haemorrhage: a nationwide cohort of 950Â 000 adults.	International Journal of Epidemiology	2019
31152163	A catalog of genetic loci associated with kidney function from analyses of a million individuals.	Nat Genet	2019
31104024	Dual-Task Performance and Neurodegeneration: Correlations Between Timed Up-and-Go Dual-Task Test Outcomes and Alzheimer's Disease Cerebrospinal Fluid Biomarkers.	Journal of Alzheimer's Disease	2019
29273807	Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.	Nat Genet	2018
28967680	Circulating proteins as predictors of incident heart failure in the elderly.	Eur J Heart Fail	2018
29875472	Glucose challenge metabolomics implicates medium-chain acylcarnitines in insulin resistance.	Sci Rep	2018
30297969	Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps.	Nat Genet	2018
30429575	Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.	Nat Genet	2018
30388399	Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.	Am J Hum Genet	2018
29858078	CRISPR/Cas9 Mediated Disruption of the Swedish APP Allele as a Therapeutic Approach for Early-Onset Alzheimer's Disease.	Mol Ther Nucleic Acids	2018
30224653	Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.	Nat Genet	2018
29549330	Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.	Nat Genet	2018
29549329	Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.	Nat Genet	2018
29632382	Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.	Nat Genet	2018