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Author Details

Jason D Weber
Washington University School of Medicine
1996
71
37
PMIDPaper TitleJournal TitlePublished Year
36951731Stromal and therapy-induced macrophage proliferation promotes PDAC progression and susceptibility to innate immunotherapy.J Exp Med2023
35155432It's Getting Complicated-A Fresh Look at p53-MDM2-ARF Triangle in Tumorigenesis and Cancer Therapy.Front Cell Dev Biol2022
33110236Evaluating the therapeutic potential of ADAR1 inhibition for triple-negative breast cancer.Oncogene2021
33564075Correction to: Evaluating the therapeutic potential of ADAR1 inhibition for triple-negative breast cancer.Oncogene2021
33983438Evaluation of Racial/Ethnic Differences in Treatment and Mortality Among Women With Triple-Negative Breast Cancer.JAMA Oncol2021
33335292Upregulation of 5'-terminal oligopyrimidine mRNA translation upon loss of the ARF tumor suppressor.Sci Rep2020
31120565Race and risk of subsequent aggressive breast cancer following ductal carcinoma in situ.Cancer2019
31727116Associations of race and ethnicity with risk of developing invasive breast cancer after lobular carcinoma in situ.Breast Cancer Res2019
31182639DHX33 Interacts with AP-2β To Regulate <i>Bcl-2</i> Gene Expression and Promote Cancer Cell Survival.Mol Cell Biol2019
30619092The Role of RNA Editing in Cancer Development and Metabolic Disorders.Front Endocrinol (Lausanne)2018
30224629Recurrent WNT pathway alterations are frequent in relapsed small cell lung cancer.Nat Commun2018
28148777Sabotaging of the oxidative stress response by an oncogenic noncoding RNA.FASEB J2017
27601587DHX33 Transcriptionally Controls Genes Involved in the Cell Cycle.Mol Cell Biol2016
25888162Targeting PTEN-defined breast cancers with a one-two punch.Breast Cancer Res2015
26100019The DHX33 RNA Helicase Promotes mRNA Translation Initiation.Mol Cell Biol2015
25915396Correction: Synergistic Effects of Concurrent Blockade of PI3K and MEK Pathways in Pancreatic Cancer Preclinical Models.PLoS One2015
23318441The ARF tumor-suppressor controls Drosha translation to prevent Ras-driven transformation.Oncogene2014
25260534Elevated DDX21 regulates c-Jun activity and rRNA processing in human breast cancers.Breast Cancer Res2014
24916693TP53 mutations and lung cancer: not all mutations are created equal.Clin Cancer Res2014
24525025ARF tumor suppression in the nucleolus.Biochim Biophys Acta2014
24726362ARF and p53 coordinate tumor suppression of an oncogenic IFN-β-STAT1-ISG15 signaling axis.Cell Rep2014
23508101Forget transcription: translation is where the action is.Mol Cell Biol2013
23746840Posttranscriptional control of T cell effector function by aerobic glycolysis.Cell2013
23401854P19ARF and RasV¹² offer opposing regulation of DHX33 translation to dictate tumor cell fate.Mol Cell Biol2013
22064482Hypergrowth mTORC1 signals translationally activate the ARF tumor suppressor checkpoint.Mol Cell Biol2012
22722193Whole-genome analysis informs breast cancer response to aromatase inhibition.Nature2012
22860046Cathepsin K-Cre causes unexpected germline deletion of genes in mice.PLoS One2012
22214661Deconvoluting mTOR biology.Cell Cycle2012
22382782Knocking down nucleolin expression in gliomas inhibits tumor growth and induces cell cycle arrest.J Neurooncol2012
20802533Identification of FUSE-binding protein 1 as a regulatory mRNA-binding protein that represses nucleophosmin translation.Oncogene2011
21970857Loss of Trop2 promotes carcinogenesis and features of epithelial to mesenchymal transition in squamous cell carcinoma.Mol Cancer Res2011
21937682RNA helicase DDX5 is a p53-independent target of ARF that participates in ribosome biogenesis.Cancer Res2011
21930779Identification of DHX33 as a mediator of rRNA synthesis and cell growth.Mol Cell Biol2011
20331843Nucleolar disruption ensures nuclear accumulation of p21 upon DNA damage.Traffic2010
21209895The ARF tumor suppressor regulates bone remodeling and osteosarcoma development in mice.PLoS One2010
20940396Tuberous sclerosis complex 1: an epithelial tumor suppressor essential to prevent spontaneous prostate cancer in aged mice.Cancer Res2010
20570903Synthetic lethality through combined Notch-epidermal growth factor receptor pathway inhibition in basal-like breast cancer.Cancer Res2010
19561638Nucleophosmin protein expression level, but not threonine 198 phosphorylation, is essential in growth and proliferation.Oncogene2009
19638589Nucleophosmin redistribution following heat shock: a role in heat-induced radiosensitization.Cancer Res2009
19366795PIK3CA and PIK3CB inhibition produce synthetic lethality when combined with estrogen deprivation in estrogen receptor-positive breast cancer.Cancer Res2009
18070929A non-tumor suppressor role for basal p19ARF in maintaining nucleolar structure and function.Mol Cell Biol2008
18809582Nucleophosmin serves as a rate-limiting nuclear export chaperone for the Mammalian ribosome.Mol Cell Biol2008
17510408Nucleophosmin mediates mammalian target of rapamycin-dependent actin cytoskeleton dynamics and proliferation in neurofibromin-deficient astrocytes.Cancer Res2007
17627519Therapeutic targets in the ARF tumor suppressor pathway.Curr Med Chem2007
17620057Deacetylation of the retinoblastoma tumour suppressor protein by SIRT1.Biochem J2007
17308101TSC1 sets the rate of ribosome export and protein synthesis through nucleophosmin translation.Cancer Res2007
17503347Mammalian target of rapamycin: master regulator of cell growth in the nervous system.Histol Histopathol2007
17420255c-Fms tyrosine 559 is a major mediator of M-CSF-induced proliferation of primary macrophages.J Biol Chem2007
16648475Nucleophosmin is essential for ribosomal protein L5 nuclear export.Mol Cell Biol2006
17081987Phosphorylation-dependent ubiquitination of cyclin D1 by the SCF(FBX4-alphaB crystallin) complex.Mol Cell2006
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Collaborators

Leonard B Maggi
Washington University School of Medicine
Co-authored papers 19
Charles J Sherr
St. Jude Children's Research Hospital
Co-authored papers 7
Martine F Roussel
St. Jude Children's Research Hospital
Co-authored papers 6
David H Gutmann
Co-authored papers 6
Mark A Watson
Washington University School of Medicine
Co-authored papers 3
Reid Townsend
Co-authored papers 3
Graham A Colditz
Washington University School of Medicine
Co-authored papers 3
Matthew J Ellis
Co-authored papers 2
Richard K Wilson
The Ohio State University
Co-authored papers 2
Jacqueline Snider
Co-authored papers 2
Ramaswamy Govindan
Siteman Cancer Center, Washington University School of Medicine
Co-authored papers 2
Jeremy Hoog
Co-authored papers 2
Elaine R Mardis
The Ohio State University
Co-authored papers 2
Robert S Fulton
McDonnell Genome Institute, Washington University School of Medicine
Co-authored papers 2
Theodore C Goldstein
Bakar Computational Health Sciences Institute, University of California san francisco
Co-authored papers 1
Avinash Ramu
Washington University School of Medicine
Co-authored papers 1
Joel S Parker
Lineberger Cancer Center, University of North Carolina
Co-authored papers 1
Jon H Ritter
Washington University School of Medicine
Co-authored papers 1
Melissa H Cessna
Intermountain Medical Center
Co-authored papers 1
Sherri R Davies
Co-authored papers 1
Peter A Humphrey
Yale University School of Medicine
Co-authored papers 1
Cyriac Kandoth
University of California los angeles
Co-authored papers 1
Jerold E Rehg
St. Jude Children's Research Hospital
Co-authored papers 1
Ashiq Masood
Indiana University Melvin and Bren Simon Comprehensive Cancer Center
Co-authored papers 1
David G Huntsman
University of British Columbia
Co-authored papers 1
Rachelle R Olsen
Huntsman Cancer Institute, University of Utah
Co-authored papers 1
Mei-Ling Kuo
Kaohsiung Chang Gung Memorial Hospital
Co-authored papers 1
Angela C Hirbe
Washington University School of Medicine and Siteman Cancer Center
Co-authored papers 1
Paul K Marcom
Co-authored papers 1
Kilannin Krysiak
Washington University School of Medicine
Co-authored papers 1
Release 1.2