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Author Details

Udo Oppermann
Botnar Research Centre, University of Oxford
1991
236
63
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36631435Prolyl-tRNA synthetase as a novel therapeutic target in multiple myeloma.Blood Cancer J2023
37558953Phenotypic Chemical Screening in CD4<sup>+</sup> T Cells to Identify Epigenetic Inhibitors.Methods Mol Biol2023
37077385Discovery of a Potent and Selective Naphthyridine-Based Chemical Probe for Casein Kinase 2.ACS Med Chem Lett2023
37132223HSD3B1 is an oxysterol 3β-hydroxysteroid dehydrogenase in human placenta.Open Biol2023
36781734Long-Read Single-Cell Sequencing Using scCOLOR-seq.Methods Mol Biol2023
36746923Correction: Prolyl-tRNA synthetase as a novel therapeutic target in multiple myeloma.Blood Cancer J2023
36909530BRD9-SMAD2/3 orchestrates stemness and tumorigenesis in pancreatic ductal adenocarcinoma.bioRxiv2023
35064676Immune response to COVID-19 vaccination is attenuated by poor disease control and antimyeloma therapy with vaccine driven divergent T-cell response.Br J Haematol2022
36612090Prospective Assessment of Tumour Burden and Bone Disease in Plasma Cell Dyscrasias Using DW-MRI and Exploratory Bone Biomarkers.Cancers (Basel)2022
36008486Elucidating the path to Plasmodium prolyl-tRNA synthetase inhibitors that overcome halofuginone resistance.Nat Commun2022
35164245Recognition of Dimethylarginine Analogues by Tandem Tudor Domain Protein Spindlin1.Molecules2022
33402692Somatostatin receptor 2 expression in nasopharyngeal cancer is induced by Epstein Barr virus infection: impact on prognosis, imaging and therapy.Nat Commun2021
33717143Dissecting the Role of BET Bromodomain Proteins BRD2 and BRD4 in Human NK Cell Function.Front Immunol2021
33791697The Prolyl-tRNA Synthetase Inhibitor Halofuginone Inhibits SARS-CoV-2 Infection.bioRxiv2021
33786580KDM5 inhibition offers a novel therapeutic strategy for the treatment of KMT2D mutant lymphomas.Blood2021
34433639Neuropeptide S receptor 1 is a nonhormonal treatment target in endometriosis.Sci Transl Med2021
34638429SSTR2 in Nasopharyngeal Carcinoma: Relationship with Latent EBV Infection and Potential as a Therapeutic Target.Cancers (Basel)2021
34843649First-in-Class Inhibitors of the Ribosomal Oxygenase MINA53.J Med Chem2021
33968920A Chemo-Genomic Approach Identifies Diverse Epigenetic Therapeutic Vulnerabilities in MYCN-Amplified Neuroblastoma.Front Cell Dev Biol2021
34215314AF10 (MLLT10) prevents somatic cell reprogramming through regulation of DOT1L-mediated H3K79 methylation.Epigenetics Chromatin2021
34211161Nanopore sequencing of single-cell transcriptomes with scCOLOR-seq.Nat Biotechnol2021
34263697Cereblon pathway biomarkers and immune profiles in patients with myeloma receiving post-ASCT lenalidomide maintenance (LEOPARD).Leuk Lymphoma2021
34258103Lysine Demethylase 5A is Required for MYC Driven Transcription in Multiple Myeloma.Blood Cancer Discov2021
32403198GGPS1 Mutations Cause Muscular Dystrophy/Hearing Loss/Ovarian Insufficiency Syndrome.Ann Neurol2020
32001775Amine oxidase 3 is a novel pro-inflammatory marker of oxidative stress in peritoneal endometriosis lesions.Sci Rep2020
31907005Mass cytometry analysis reveals a distinct immune environment in peritoneal fluid in endometriosis: a characterisation study.BMC Med2020
33110075Globally altered epigenetic landscape and delayed osteogenic differentiation in H3.3-G34W-mutant giant cell tumor of bone.Nat Commun2020
32855205Inhibition of Histone H3K27 Demethylases Inactivates Brachyury (TBXT) and Promotes Chordoma Cell Death.Cancer Res2020
32123118Histone H3K27me3 demethylases regulate human Th17 cell development and effector functions by impacting on metabolism.Proc Natl Acad Sci U S A2020
32304986Advances and challenges in epigenomic single-cell sequencing applications.Curr Opin Chem Biol2020
32205848Author Correction: Amine oxidase 3 is a novel pro-inflammatory marker of oxidative stress in peritoneal endometriosis lesions.Sci Rep2020
30431220Design, Synthesis and Characterization of Covalent KDM5 Inhibitors.Angew Chem Int Ed Engl2019
31772153The fungal metabolite chaetocin is a sensitizer for pro-apoptotic therapies in glioblastoma.Cell Death Dis2019
31659163Aspartate/asparagine-β-hydroxylase crystal structures reveal an unexpected epidermal growth factor-like domain substrate disulfide pattern.Nat Commun2019
31303423Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome.Cancer Cell2019
31526763Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome.Cancer Cell2019
31550156A Chemical Probe for Tudor Domain Protein Spindlin1 to Investigate Chromatin Function.J Med Chem2019
31260300Discovery of a Potent and Selective Fragment-like Inhibitor of Methyllysine Reader Protein Spindlin 1 (SPIN1).J Med Chem2019
30984471A Parsimonious Mechanism of Sugar Dehydration by Human GDP-Mannose-4,6-dehydratase.ACS Catal2019
30867043Divergent roles of prostacyclin and PGE<sub>2</sub> in human tendinopathy.Arthritis Res Ther2019
31114671Immunophenotypic expression of UCP1 in hibernoma and other adipose/non adipose soft tissue tumours.Clin Sarcoma Res2019
30853107Role of protein structure in variant annotation: structural insight of mutations causing 6-pyruvoyl-tetrahydropterin synthase deficiency.Pathology2019
30996803Identification of the 2-Benzoxazol-2-yl-phenol Scaffold as New Hit for JMJD3 Inhibition.ACS Med Chem Lett2019
30962627Bromodomain inhibition of the coactivators CBP/EP300 facilitate cellular reprogramming.Nat Chem Biol2019
30427558Selective Inhibitors of a Human Prolyl Hydroxylase (OGFOD1) Involved in Ribosomal Decoding.Chemistry2019
29301935Inhibition of histone H3K27 demethylases selectively modulates inflammatory phenotypes of natural killer cells.J Biol Chem2018
29880640Structural insight into the human mitochondrial tRNA purine N1-methyltransferase and ribonuclease P complexes.J Biol Chem2018
30202513Periostin expression in neoplastic and non-neoplastic diseases of bone and joint.Clin Sarcoma Res2018
29899950Non-competitive cyclic peptides for targeting enzyme-substrate complexes.Chem Sci2018
29449935Pleomorphic liposarcoma of bone: a rare primary malignant bone tumour.Clin Sarcoma Res2018
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Collaborators

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Karolinska Institutet
Co-authored papers 15
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Co-authored papers 12
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Sungkyunkwan University
Co-authored papers 11
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Co-authored papers 9
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Co-authored papers 7
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University of Oxford
Co-authored papers 6
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Co-authored papers 6
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Co-authored papers 5
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Co-authored papers 5
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Co-authored papers 3
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Co-authored papers 3
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University of Toronto
Co-authored papers 3
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Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Co-authored papers 3
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Co-authored papers 3
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Institute of Pathology, Medical University of Innsbruck
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Kyoto University
Co-authored papers 2
Christopher P Austin
St. George's University Medical School
Co-authored papers 2
Thomas B Acton
Center for Advanced Biotechnology and Medicine, The State University of New Jersey
Co-authored papers 2
Jun Qi
Dana-Farber Cancer Institute
Co-authored papers 2
S??ren Matzk
Max Planck Institute for Molecular Genetics
Co-authored papers 2
Dinshaw J Patel
Memorial Sloan-Kettering Cancer Center
Co-authored papers 2
Marie-Laure Yaspo
Max Planck Institute for Molecular Genetics
Co-authored papers 2
Gaetano T Montelione
Rensselaer Polytechnic Institute
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Peter J Ratcliffe
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Mitchell J Weiss
Co-authored papers 2
Pamela J Thomas
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Release 1.2