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Author Details
Full Name
Margaret E Glasner
Affiliation
Texas A&M University, College Station
ORCID
Career Start Year
2000
Papers
24
H Index
16
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
34845903
Second-Shell Amino Acid R266 Helps Determine <i>N</i>-Succinylamino Acid Racemase Reaction Specificity in Promiscuous <i>N</i>-Succinylamino Acid Racemase/<i>o</i>-Succinylbenzoate Synthase Enzymes.
Biochemistry
2021
31858709
How enzyme promiscuity and horizontal gene transfer contribute to metabolic innovation.
FEBS J
2020
31092555
Oxidative opening of the aromatic ring: Tracing the natural history of a large superfamily of dioxygenase domains and their relatives.
J Biol Chem
2019
29767960
Comparison of Alicyclobacillus acidocaldarius o-Succinylbenzoate Synthase to Its Promiscuous N-Succinylamino Acid Racemase/ o-Succinylbenzoate Synthase Relatives.
Biochemistry
2018
28183934
Finding enzymes in the gut metagenome.
Science
2017
24955846
Role of an active site loop in the promiscuous activities of Amycolatopsis sp. T-1-60 NSAR/OSBS.
Biochemistry
2014
24872444
Loss of quaternary structure is associated with rapid sequence divergence in the OSBS family.
Proc Natl Acad Sci U S A
2014
24937446
Promiscuity of Exiguobacterium sp. AT1b o-succinylbenzoate synthase illustrates evolutionary transitions in the OSBS family.
Biochem Biophys Res Commun
2014
24060347
Divergent evolution of ligand binding in the o-succinylbenzoate synthase family.
Biochemistry
2013
22775324
Residues required for activity in Escherichia coli o-succinylbenzoate synthase (OSBS) are not conserved in all OSBS enzymes.
Biochemistry
2012
19219566
Target selection and annotation for the structural genomics of the amidohydrolase and enolase superfamilies.
J Struct Funct Genomics
2009
19220063
Evolution of enzymatic activities in the enolase superfamily: stereochemically distinct mechanisms in two families of cis,cis-muconate lactonizing enzymes.
Biochemistry
2009
19000819
Discovery of a dipeptide epimerase enzymatic function guided by homology modeling and virtual screening.
Structure
2008
18754693
Evolution of enzymatic activities in the enolase superfamily: L-rhamnonate dehydratase.
Biochemistry
2008
17124868
Mechanisms of protein evolution and their application to protein engineering.
Adv Enzymol Relat Areas Mol Biol
2007
17944491
Evolution of enzymatic activities in the enolase superfamily: D-Mannonate dehydratase from Novosphingobium aromaticivorans.
Biochemistry
2007
17603539
Prediction and assignment of function for a divergent N-succinyl amino acid racemase.
Nat Chem Biol
2007
16935022
Evolution of enzyme superfamilies.
Curr Opin Chem Biol
2006
16740275
Evolution of structure and function in the o-succinylbenzoate synthase/N-acylamino acid racemase family of the enolase superfamily.
J Mol Biol
2006
15774722
MicroRNAs regulate brain morphogenesis in zebrafish.
Science
2005
12624257
Vertebrate microRNA genes.
Science
2003
12069603
Metal ion requirements for structure and catalysis of an RNA ligase ribozyme.
Biochemistry
2002
11358999
RNA-catalyzed RNA polymerization: accurate and general RNA-templated primer extension.
Science
2001
11112542
Recognition of nucleoside triphosphates during RNA-catalyzed primer extension.
Biochemistry
2000
1 - 24 of 24
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