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Author Details

Heidi Lyng
Radiumhospitalet, Oslo University Hosptial
1990
101
31
PMIDPaper TitleJournal TitlePublished Year
36585179Exploring Hypoxia in Prostate Cancer With T2-weighted Magnetic Resonance Imaging Radiomics and Pimonidazole Scoring.Anticancer Res2023
37640161Prostate cancer radiogenomics reveals proliferative gene expression programs associated with distinct MRI-based hypoxia levels.Radiother Oncol2023
35332267A prognostic hypoxia gene signature with low heterogeneity within the dominant tumour lesion in prostate cancer patients.Br J Cancer2022
36240006Targeted Therapy on the Screen: Do We Hit the Target?Clin Cancer Res2022
36113778Risk of recurrence after chemoradiotherapy identified by multimodal MRI and 18F-FDG-PET/CT in locally advanced cervical cancer.Radiother Oncol2022
35064630miR-200a/b/-429 downregulation is a candidate biomarker of tumor radioresistance and independent of hypoxia in locally advanced cervical cancer.Mol Oncol2022
34513278Amino acid transporter expression and 18F-FACBC uptake at PET in primary prostate cancer.Am J Nucl Med Mol Imaging2021
33525508Tumor Hypoxia as a Barrier in Cancer Therapy: Why Levels Matter.Cancers (Basel)2021
32606004MRI Distinguishes Tumor Hypoxia Levels of Different Prognostic and Biological Significance in Cervical Cancer.Cancer Res2020
32580139Combining imaging- and gene-based hypoxia biomarkers in cervical cancer improves prediction of chemoradiotherapy failure independent of intratumour heterogeneity.EBioMedicine2020
30660934Reference MicroRNAs for RT-qPCR Assays in Cervical Cancer Patients and Their Application to Studies of HPV16 and Hypoxia Biomarkers.Transl Oncol2019
31264167Influx rate of <sup>18</sup>F-fluoroaminosuberic acid reflects cystine/glutamate antiporter expression in tumour xenografts.Eur J Nucl Med Mol Imaging2019
30888866<i>PTEN</i> Expression in Prostate Cancer: Relationship With Clinicopathologic Features and Multiparametric MRI Findings.AJR Am J Roentgenol2019
30856376Mitochondrial Function of CKS2 Oncoprotein Links Oxidative Phosphorylation with Cell Division in Chemoradioresistant Cervical Cancer.Neoplasia2019
29630428Low dose-rate irradiation with [<sup>3</sup>H]-labelled valine to selectively target hypoxic cells in a human colorectal cancer xenograft model.Acta Oncol2018
29945958Combined MR Imaging of Oxygen Consumption and Supply Reveals Tumor Hypoxia and Aggressiveness in Prostate Cancer Patients.Cancer Res2018
30294681Potentials and challenges of diffusion-weighted magnetic resonance imaging in radiotherapy.Clin Transl Radiat Oncol2018
30294508Transkingdom network reveals bacterial players associated with cervical cancer gene expression program.PeerJ2018
28804704Hypoxia in cervical cancer: from biology to imaging.Clin Transl Imaging2017
28464746Autodelineation of cervical cancers using multiparametric magnetic resonance imaging and machine learning.Acta Oncol2017
26791779Hypoxia-induced alterations of G2 checkpoint regulators.Mol Oncol2016
27599042Hypoxia-independent gene expression signature associated with radiosensitisation of prostate cancer cell lines by histone deacetylase inhibition.Br J Cancer2016
27564398Cluster analysis of dynamic contrast enhanced MRI reveals tumor subregions related to locoregional relapse for cervical cancer patients.Acta Oncol2016
27270309Aberrant methylation-mediated silencing of microRNAs contributes to HPV-induced anchorage independence.Oncotarget2016
27244197Identification and Validation of Reference Genes for RT-qPCR Studies of Hypoxia in Squamous Cervical Cancer Patients.PLoS One2016
27012812Integrative Analysis of DCE-MRI and Gene Expression Profiles in Construction of a Gene Classifier for Assessment of Hypoxia-Related Risk of Chemoradiotherapy Failure in Cervical Cancer.Clin Cancer Res2016
25347767Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium.J Enzyme Inhib Med Chem2015
26291246Interplay between promoter methylation and chromosomal loss in gene silencing at 3p11-p14 in cervical cancer.Epigenetics2015
25461803The tumour hypoxia marker pimonidazole reflects a transcriptional programme associated with aggressive prostate cancer.Br J Cancer2015
24674660Ménage à trois: an evolutionary interplay between human papillomavirus, a tumor, and a woman.Trends Microbiol2014
24802069Classification of dynamic contrast enhanced MR images of cervical cancers using texture analysis and support vector machines.IEEE Trans Med Imaging2014
23333024Pharmacokinetic parameters derived from dynamic contrast enhanced MRI of cervical cancers predict chemoradiotherapy outcome.Radiother Oncol2013
24035332Hypoxia-independent downregulation of hypoxia-inducible factor 1 targets by androgen deprivation therapy in prostate cancer.Int J Radiat Oncol Biol Phys2013
23651994Gene network reconstruction reveals cell cycle and antiviral genes as major drivers of cervical cancer.Nat Commun2013
23335387Identification of eight candidate target genes of the recurrent 3p12-p14 loss in cervical cancer by integrative genomic profiling.J Pathol2013
22014954Dynamic contrast-enhanced MRI of cervical cancers: temporal percentile screening of contrast enhancement identifies parameters for prediction of chemoradioresistance.Int J Radiat Oncol Biol Phys2012
22890239Hypoxia-induced gene expression in chemoradioresistant cervical cancer revealed by dynamic contrast-enhanced MRI.Cancer Res2012
22621752Vascular responses to radiotherapy and androgen-deprivation therapy in experimental prostate cancer.Radiat Oncol2012
21325885Three independent mechanisms for arrest in G2 after ionizing radiation.Cell Cycle2011
23089821Weighted lasso with data integration.Stat Appl Genet Mol Biol2011
21767185Pharmacokinetic analysis and k-means clustering of DCEMR images for radiotherapy outcome prediction of advanced cervical cancers.Acta Oncol2011
21737508Membranous expression of ectodomain isoforms of the epidermal growth factor receptor predicts outcome after chemoradiotherapy of lymph node-negative cervical cancer.Clin Cancer Res2011
21680035Phosphorylation of EGFR measured with in situ proximity ligation assay: relationship to EGFR protein level and gene dosage in cervical cancer.Radiother Oncol2011
19513498Expression of 14-3-3sigma in cervical squamous cell carcinomas: relationship with clinical outcome.Oncol Rep2009
19911042Gene dosage, expression, and ontology analysis identifies driver genes in the carcinogenesis and chemoradioresistance of cervical cancer.PLoS Genet2009
18358079Indirect genomic effects on survival from gene expression data.Genome Biol2008
19440467Human papillomavirus DNA and e6/e7 mRNA status in relation to survival of patients treated for cervical squamous cell carcinoma.Open Virol J2008
18500990GeneCount: genome-wide calculation of absolute tumor DNA copy numbers from array comparative genomic hybridization data.Genome Biol2008
18513391Validation of oligoarrays for quantitative exploration of the transcriptome.BMC Genomics2008
17233882Metabolic mapping by use of high-resolution magic angle spinning 1H MR spectroscopy for assessment of apoptosis in cervical carcinomas.BMC Cancer2007
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Collaborators

Marit Holden
University of Mainz
Co-authored papers 6
Ingrid K Glad
University of Oslo
Co-authored papers 5
Eivind Hovig
Center for Bioinformatics, University of Oslo
Co-authored papers 4
Arnoldo Frigessi
University of Oslo
Co-authored papers 4
Ola Myklebost
Institute for Cancer Research, Oslo University Hospital
Co-authored papers 3
Jahn M Nesland
The Norwegian Radium Hospital, Oslo University Hospital
Co-authored papers 2
Mark A van de Wiel
Amsterdam University Medical Centers (Amsterdam UMC)
Co-authored papers 2
Wolfgang Lilleby
Oslo University Hospital
Co-authored papers 2
Vigdis Nygaard
Institute for Cancer Research, Oslo University Hospital
Co-authored papers 1
Jeffrey M Trimarchi
Inc., Lehigh University
Co-authored papers 1
Albert J van der Kogel
University of Wisconsin School of Medicine and Public Health
Co-authored papers 1
Johan Bussink
Radboud University, Nijmegen Medical Centre
Co-authored papers 1
Syed Haider
Institute of Cancer Research
Co-authored papers 1
Philippe Lambin
Maastricht University
Co-authored papers 1
Lucila Ohno-Machado
Co-authored papers 1
Egil Ferkingstad
Co-authored papers 1
Constance L Cepko
Howard Hughes Medical Institute, Harvard Medical School
Co-authored papers 1
Winston Patrick Kuo
Harvard School of Dental Medicine
Co-authored papers 1
Fang Liu
Institute for Cancer Research, Norwegian Radium Hospital
Co-authored papers 1
Adrian L Harris
University of Oxford
Co-authored papers 1
Ludwig Dubois
Maastricht University
Co-authored papers 1
Lucila Ohno-Machado
Escola de Administracao de Empresas - FGV, Stanford University, University of California San Diego, University of Sao Paulo, Yale School of Medicine
Co-authored papers 1
Bradly G Wouters
Princess Margaret Cancer Centre, University Health Network and, University of Toronto
Co-authored papers 1
Marianne Koritzinsky
Princess Margaret Cancer Centre University Health Network
Co-authored papers 1
Sudhir Varma
Center for Cancer Research, National Cancer Institute
Co-authored papers 1
Tao Deng
Co-authored papers 1
Francesca M Buffa
University of Oxford
Co-authored papers 1
Ralph T H Leijenaar
Maastricht University Medical Center (MUMC+)
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Release 1.2