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Author Details

Michael L Klein
Casey Eye Institute, Oregon Health & Science University
1974
133
58
PMIDPaper TitleJournal TitlePublished Year
37153444Ultra-rare complement factor 8 coding variants in families with age-related macular degeneration.iScience2023
34929159Extracellular matrix dysfunction in Sorsby patient-derived retinal pigment epithelium.Exp Eye Res2022
31899035Incidence of Macular Atrophy after Untreated Neovascular Age-Related Macular Degeneration: Age-Related Eye Disease Study Report 40.Ophthalmology2020
32087877Reply.Ophthalmology2020
31120506Assessment of Novel Genome-Wide Significant Gene Loci and Lesion Growth in Geographic Atrophy Secondary to Age-Related Macular Degeneration.JAMA Ophthalmol2019
31358387No CFH or ARMS2 Interaction with Omega-3 Fatty Acids, Low versus High Zinc, or β-Carotene versus Lutein and Zeaxanthin on Progression of Age-Related Macular Degeneration in the Age-Related Eye Disease Study 2: Age-Related Eye Disease Study 2 Report No. 18.Ophthalmology2019
31153849Precursors and Development of Geographic Atrophy with Autofluorescence Imaging: Age-Related Eye Disease Study 2 Report Number 18.Ophthalmol Retina2019
29346644Genome-wide analysis of disease progression in age-related macular degeneration.Hum Mol Genet2018
30060980Progression of Geographic Atrophy in Age-related Macular Degeneration: AREDS2 Report Number 16.Ophthalmology2018
30571798Correction: A 32 kb Critical Region Excluding Y402H in CFH Mediates Risk for Age-Related Macular Degeneration.PLoS One2018
28613221CLINICOPATHOLOGIC CORRELATION OF RETINAL ANGIOMATOUS PROLIFERATION TREATED WITH RANIBIZUMAB.Retina2017
28341650Bivariate Analysis of Age-Related Macular Degeneration Progression Using Genetic Risk Scores.Genetics2017
26691988A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.Nat Genet2016
25456150Genetic testing in persons with age-related macular degeneration and the use of the AREDS supplements: to test or not to test?Ophthalmology2015
26354764Joint Associations of Diet, Lifestyle, and Genes with Age-Related Macular Degeneration.Ophthalmology2015
26398062Reply: To PMID 25456150.Ophthalmology2015
26398060Reply: To PMID 25456150.Ophthalmology2015
26398054Reply: To PMID 25456150.Ophthalmology2015
26210599Author reply: To PMID 24974817.Ophthalmology2015
25962167Clinical and genetic factors associated with progression of geographic atrophy lesions in age-related macular degeneration.PLoS One2015
24084496Risk of geographic atrophy in the comparison of age-related macular degeneration treatments trials.Ophthalmology2014
25488058Prevalence of anti-retinal autoantibodies in different stages of Age-related macular degeneration.BMC Ophthalmol2014
24974817No clinically significant association between CFH and ARMS2 genotypes and response to nutritional supplements: AREDS report number 38.Ophthalmology2014
24899048Rare and common variants in extracellular matrix gene Fibrillin 2 (FBN2) are associated with macular degeneration.Hum Mol Genet2014
24932431Retinal and Choroidal Imaging With 870-nm Spectral-Domain OCT Compared With 1050-nm Spectral-Domain OCT, With and Without Enhanced Depth Imaging.Transl Vis Sci Technol2014
24679442Quantitative optical coherence tomography angiography of choroidal neovascularization in age-related macular degeneration.Ophthalmology2014
24346170Genetic evidence for role of carotenoids in age-related macular degeneration in the Carotenoids in Age-Related Eye Disease Study (CAREDS).Invest Ophthalmol Vis Sci2014
24310343Secondary analyses of the effects of lutein/zeaxanthin on age-related macular degeneration progression: AREDS2 report No. 3.JAMA Ophthalmol2014
23047002Baseline predictors for one-year visual outcomes with ranibizumab or bevacizumab for neovascular age-related macular degeneration.Ophthalmology2013
24036949Identification of a rare coding variant in complement 3 associated with age-related macular degeneration.Nat Genet2013
23645227Lutein/zeaxanthin for the treatment of age-related cataract: AREDS2 randomized trial report no. 4.JAMA Ophthalmol2013
23404124Genetic determinants of macular pigments in women of the Carotenoids in Age-Related Eye Disease Study.Invest Ophthalmol Vis Sci2013
23455636Seven new loci associated with age-related macular degeneration.Nat Genet2013
23190755Vitamin D intake and season modify the effects of the GC and CYP2R1 genes on 25-hydroxyvitamin D concentrations.J Nutr2013
23337555Pharmacogenetics for genes associated with age-related macular degeneration in the Comparison of AMD Treatments Trials (CATT).Ophthalmology2013
22761647The related transcriptional enhancer factor-1 isoform, TEAD4(216), can repress vascular endothelial growth factor expression in mammalian cells.PLoS One2012
23177625Hypomethylation of the IL17RC promoter associates with age-related macular degeneration.Cell Rep2012
20970772Clinicopathologic correlation of choroidal and retinal neovascular lesions in age-related macular degeneration.Am J Ophthalmol2011
22022419A 32 kb critical region excluding Y402H in CFH mediates risk for age-related macular degeneration.PLoS One2011
21825180Risk assessment model for development of advanced age-related macular degeneration.Arch Ophthalmol2011
21762495Complement component C5a promotes expression of IL-22 and IL-17 from human T cells and its implication in age-related macular degeneration.J Transl Med2011
21887094Update on the role of genetics in the onset of age-related macular degeneration.Clin Ophthalmol2011
21882290Evidence of association of APOE with age-related macular degeneration: a pooled analysis of 15 studies.Hum Mutat2011
21498624Variations in apolipoprotein E frequency with age in a pooled analysis of a large group of older people.Am J Epidemiol2011
21482873Vitamin D status and early age-related macular degeneration in postmenopausal women.Arch Ophthalmol2011
21149749Healthy lifestyles related to subsequent prevalence of age-related macular degeneration.Arch Ophthalmol2011
20079925Natural history of drusenoid pigment epithelial detachment in age-related macular degeneration: Age-Related Eye Disease Study Report No. 28.Ophthalmology2010
20861866Genome-wide association identifies SKIV2L and MYRIP as protective factors for age-related macular degeneration.Genes Immun2010
20385819Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration.Proc Natl Acad Sci U S A2010
20381870Progression of geographic atrophy and genotype in age-related macular degeneration.Ophthalmology2010
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Collaborators

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Co-authored papers 19
The EMMES Corporation
Co-authored papers 18
Regeneron Pharmaceuticals Inc.
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Co-authored papers 16
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University of Massachusetts Chan Medical School
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Jules Stein Eye Institute
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The University of Melbourne
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Royal Victorian Eye and Ear Hospital, the University of Melbourne
Co-authored papers 6
Karolinska Institutet
Co-authored papers 5
UCL Institute of Ophthalmology, University College London
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The Wilmer Eye Institute, Johns Hopkins University School of Medicine
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Kaiser Permanente San Francisco Medical Center
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