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Author Details

F??tima Al-Shahrour
Spanish National Cancer Research Centre (CNIO)
2003
108
44
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36928090Kras oncogene ablation prevents resistance in advanced lung adenocarcinomas.J Clin Invest2023
37483622Dimethyl fumarate-related immune and transcriptional signature is associated with clinical response in multiple sclerosis-treated patients.Front Immunol2023
36947705PD-L1<sup>ATTAC</sup> mice reveal the potential of depleting PD-L1 expressing cells in cancer therapy.Aging (Albany NY)2023
37207338PanDrugs2: prioritizing cancer therapies using integrated individual multi-omics data.Nucleic Acids Res2023
36854674Genomic and immune landscape Of metastatic pheochromocytoma and paraganglioma.Nat Commun2023
36880458RANK is a poor prognosis marker and a therapeutic target in ER-negative postmenopausal breast cancer.EMBO Mol Med2023
36473980CALR-mutated cells are vulnerable to combined inhibition of the proteasome and the endoplasmic reticulum stress response.Leukemia2023
34788788bollito: a flexible pipeline for comprehensive single-cell RNA-seq analyses.Bioinformatics2022
35740564Peripheral Blood Mononuclear Cells Predict Therapeutic Efficacy of Immunotherapy in NSCLC.Cancers (Basel)2022
35763665Whole-genome CRISPR screening identifies N-glycosylation as a genetic and therapeutic vulnerability in CALR-mutant MPNs.Blood2022
35861150Activation of the integrated stress response is a vulnerability for multidrug-resistant FBXW7-deficient cells.EMBO Mol Med2022
35811332Bioinformatics roadmap for therapy selection in cancer genomics.Mol Oncol2022
36585418Nanobodies targeting ABCC3 for immunotargeted applications in glioblastoma.Sci Rep2022
364539933D chromatin connectivity underlies replication origin efficiency in mouse embryonic stem cells.Nucleic Acids Res2022
35870091Excess weight and anti-PD-1 immune checkpoint inhibitor's outcomes in non-small cell lung cancer.Clin Transl Oncol2022
36167809Fatty acids homeostasis during fasting predicts protection from chemotherapy toxicity.Nat Commun2022
35102208An in silico analysis identifies drugs potentially modulating the cytokine storm triggered by SARS-CoV-2 infection.Sci Rep2022
34525198IL-1 mediates microbiome-induced inflammaging of hematopoietic stem cells in mice.Blood2022
32818254DREIMT: a drug repositioning database and prioritization tool for immunomodulation.Bioinformatics2021
33846235Dianhydrogalactitol Overcomes Multiple Temozolomide Resistance Mechanisms in Glioblastoma.Mol Cancer Ther2021
34911571Beyondcell: targeting cancer therapeutic heterogeneity in single-cell RNA-seq data.Genome Med2021
34299025Inactivation of EMILIN-1 by Proteolysis and Secretion in Small Extracellular Vesicles Favors Melanoma Progression and Metastasis.Int J Mol Sci2021
34167460A comprehensive database for integrated analysis of omics data in autoimmune diseases.BMC Bioinformatics2021
31403184Hsa-miR-139-5p is a prognostic thyroid cancer marker involved in HNRNPF-mediated alternative splicing.Int J Cancer2020
33077955Midkine rewires the melanoma microenvironment toward a tolerogenic and immune-resistant state.Nat Med2020
32747363Endothelin-1-Mediated Drug Resistance in <i>EGFR</i>-Mutant Non-Small Cell Lung Carcinoma.Cancer Res2020
32636365A user guide for the online exploration and visualization of PCAWG data.Nat Commun2020
32504002Interpreting molecular similarity between patients as a determinant of disease comorbidity relationships.Nat Commun2020
32499301Discovery of New Targets to Control Metastasis in Pancreatic Cancer by Single-cell Transcriptomics Analysis of Circulating Tumor Cells.Mol Cancer Ther2020
32350726Metatax: Metataxonomics with a Compi-Based Pipeline for Precision Medicine.Interdiscip Sci2020
29077790Precision medicine needs pioneering clinical bioinformaticians.Brief Bioinform2019
31801092Global Transcriptomic Profiling of the Bone Marrow Stromal Microenvironment during Postnatal Development, Aging, and Inflammation.Cell Rep2019
31655559The use of PanDrugs to prioritize anticancer drug treatments in a case of T-ALL based on individual genomic data.BMC Cancer2019
31678770The correlation between immune subtypes and consensus molecular subtypes in colorectal cancer identifies novel tumour microenvironment profiles, with prognostic and therapeutic implications.Eur J Cancer2019
31273063CXCR7 Reactivates ERK Signaling to Promote Resistance to EGFR Kinase Inhibitors in NSCLC.Cancer Res2019
31410193Integrative multi-omics analysis identifies a prognostic miRNA signature and a targetable miR-21-3p/TSC2/mTOR axis in metastatic pheochromocytoma/paraganglioma.Theranostics2019
31540260In Silico Drug Prescription for Targeting Cancer Patient Heterogeneity and Prediction of Clinical Outcome.Cancers (Basel)2019
30975481Complete Regression of Advanced Pancreatic Ductal Adenocarcinomas upon Combined Inhibition of EGFR and C-RAF.Cancer Cell2019
31173067vulcanSpot: a tool to prioritize therapeutic vulnerabilities in cancer.Bioinformatics2019
30700761Clonal dynamics monitoring during clinical evolution in chronic lymphocytic leukaemia.Sci Rep2019
29351990Saa3 is a key mediator of the protumorigenic properties of cancer-associated fibroblasts in pancreatic tumors.Proc Natl Acad Sci U S A2018
30158526In vivo phosphoproteomics reveals kinase activity profiles that predict treatment outcome in triple-negative breast cancer.Nat Commun2018
30090102Immunophenotype and Transcriptome Profile of Patients With Multiple Sclerosis Treated With Fingolimod: Setting Up a Model for Prediction of Response in a 2-Year Translational Study.Front Immunol2018
29848362PanDrugs: a novel method to prioritize anticancer drug treatments according to individual genomic data.Genome Med2018
29761480Whole exome sequencing identifies PLEC, EXO5 and DNAH7 as novel susceptibility genes in testicular cancer.Int J Cancer2018
27582484Targeted Sequencing Reveals Low-Frequency Variants in <i>EPHA</i> Genes as Markers of Paclitaxel-Induced Peripheral Neuropathy.Clin Cancer Res2017
28436985Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells.Nat Genet2017
28453706Somatic BRCA2 bi-allelic loss in the primary prostate cancer was associated to objective response to PARPi in a sporadic CRPC patient.Ann Oncol2017
28858862Pancreas Cancer Precision Treatment Using Avatar Mice from a Bioinformatics Perspective.Public Health Genomics2017
28667284A molecular hypothesis to explain direct and inverse co-morbidities between Alzheimer's Disease, Glioblastoma and Lung cancer.Sci Rep2017
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Collaborators

Joaqu??n Dopazo
Andalusian Public Foundation Progress and Health-FPS
Co-authored papers 33
Benjamin L Ebert
Co-authored papers 15
David Montaner
Co-authored papers 13
Alfonso Valencia
Josep Carreras Leukaemia Research Institute (IJC)
Co-authored papers 8
Osvaldo Gra??a
Spanish National Cancer Research Centre-CNIO
Co-authored papers 8
Ignacio Medina
Co-authored papers 5
Cristina Rodr??guez-Antona
Spanish National Cancer Research Center (CNIO)
Co-authored papers 5
Glenn S Cowley
Broad Institute of Harvard and MIT
Co-authored papers 4
Christopher J Lengner
Co-authored papers 3
David T Scadden
Co-authored papers 3
David E Root
Broad Institute of Harvard and MIT
Co-authored papers 3
Raul Rabadan
Columbia University Vagelos College of Physicians and Surgeons
Co-authored papers 3
José Carbonell-Caballero
Co-authored papers 3
Margaret Soucheray
J. David Gladstone Institutes
Co-authored papers 3
Scott A Armstrong
Boston Children's Hospital
Co-authored papers 3
Vera Pancaldi
Universite de Toulouse, Inserm, CNRS, Universite Toulouse III-Paul Sabatier
Co-authored papers 2
Marc A Marti-Renom
Universitat Pompeu Fabra (UPF)
Co-authored papers 2
Todd R Golub
Broad Institute of MIT and Harvard
Co-authored papers 2
John G Doench
Co-authored papers 2
Christina S Leslie
Co-authored papers 2
Pasi A J??nne
Dana-Farber Cancer Institute
Co-authored papers 2
Andrea Rossi
Pfizer Inc.
Co-authored papers 2
Karel Pacak
Eunice Kennedy Shriver National Institute of Child Health and Human Development
Co-authored papers 2
Ana Conesa
Institute for Integrative Systems Biology, Spanish National Research Council (CSIC)
Co-authored papers 2
Björn Nilsson
Co-authored papers 2
Nir Hacohen
Broad Institute of MIT and Harvard
Co-authored papers 2
Jose Miguel Sanchez
Co-authored papers 2
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 2
Javier Ben??tez
Instituto de Salud Carlos III
Co-authored papers 2
Markus G Manz
Co-authored papers 2
Release 1.2