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Author Details

Huasong Lu
Life Sciences Institute, Zhejiang University
2011
22
14
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36513571Reprogramming transcription after DNA damage: recognition, response, repair, and restart.Trends Cell Biol2023
34718740RNAPhaSep: a resource of RNAs undergoing phase separation.Nucleic Acids Res2022
35393539Poly(ADP-ribosylation) of P-TEFb by PARP1 disrupts phase separation to inhibit global transcription after DNA damage.Nat Cell Biol2022
34916618Rolling the RBP snowballs.Nat Chem Biol2022
33988507A subcellular map of the human kinome.Elife2021
35072011A natural product targets BRD4 to inhibit phase separation and gene transcription.iScience2021
32203417Phase separation of TAZ compartmentalizes the transcription machinery to promote gene expression.Nat Cell Biol2020
32520633HEXIM1 controls P-TEFb processing and regulates drug sensitivity in triple-negative breast cancer.Mol Biol Cell2020
30663929Balanced between order and disorder: a new phase in transcription elongation control and beyond.Transcription2019
29849146Phase-separation mechanism for C-terminal hyperphosphorylation of RNA polymerase II.Nature2018
26830226A Minor Subset of Super Elongation Complexes Plays a Predominant Role in Reversing HIV-1 Latency.Mol Cell Biol2016
27731797Insights into HIV-1 proviral transcription from integrative structure and dynamics of the Tat:AFF4:P-TEFb:TAR complex.Elife2016
27815197Shrimp STAT was hijacked by white spot syndrome virus immediate-early protein IE1 involved in modulation of viral genes.Fish Shellfish Immunol2016
26007649Gene target specificity of the Super Elongation Complex (SEC) family: how HIV-1 Tat employs selected SEC members to activate viral transcription.Nucleic Acids Res2015
26569506A Natural Product from Polygonum cuspidatum Sieb. Et Zucc. Promotes Tat-Dependent HIV Latency Reversal through Triggering P-TEFb's Release from 7SK snRNP.PLoS One2015
26186095Correction: Compensatory induction of MYC expression by sustained CDK9 inhibition via a BRD4-dependent mechanism.Elife2015
24367103AFF1 is a ubiquitous P-TEFb partner to enable Tat extraction of P-TEFb from 7SK snRNP and formation of SECs for HIV transactivation.Proc Natl Acad Sci U S A2014
25053741LARP7 suppresses P-TEFb activity to inhibit breast cancer progression and metastasis.Elife2014
24843025AFF4 binding to Tat-P-TEFb indirectly stimulates TAR recognition of super elongation complexes at the HIV promoter.Elife2014
23251033HIV-1 Tat recruits transcription elongation factors dispersed along a flexible AFF4 scaffold.Proc Natl Acad Sci U S A2013
23795863Viral-host interactions that control HIV-1 transcriptional elongation.Chem Rev2013
21908012An immediate-early protein of white spot syndrome virus modulates the phosphorylation of focal adhesion kinase of shrimp.Virology2011
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Collaborators

Qiang Zhou
The University of Hong Kong
Co-authored papers 17
Yuhua Xue
School of Pharmaceutical Sciences, Xiamen University
Co-authored papers 7
Ursula Schulze-Gahmen
Gladstone Institute of Virology, Gladstone Institutes San Francisco CA USA .
Co-authored papers 5
Zichong Li
Gladstone Center for HIV Cure Research, Gladstone Institute of Virology
Co-authored papers 4
Tom Alber
University of California berkeley
Co-authored papers 3
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 2
Goran Stjepanovic
Kobilka Institute of Innovative Drug Discovery, The Chinese University of Hong Kong
Co-authored papers 1
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 1
Ignacia Echeverria
University of California san francisco
Co-authored papers 1
Jeffrey R Johnson
Gladstone Institutes
Co-authored papers 1
Heather E Upton
University of California berkeley
Co-authored papers 1
Anders S Hansen
Co-authored papers 1
Avi J Samelson
Institute for Neurodegenerative Diseases, University of California san francisco
Co-authored papers 1
Ben Weisburd
Broad Institute of MIT and Harvard
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Katherine Bao
Duke University Medical Center
Co-authored papers 1
Seemay Chou
University of California - San Francisco
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Anna Nowak
Isis Pharmaceuticals, Inc.
Co-authored papers 1
James H Hurley
University of California Berkeley
Co-authored papers 1
Nanhai He
Adlai Nortye USA Inc.
Co-authored papers 1
Dina Schneidman-Duhovny
The Hebrew University of Jerusalem
Co-authored papers 1
Jennifer A Doudna
Innovative Genomics Institute, University of California berkeley
Co-authored papers 1
Yun Bai
Carnegie Institution for Science
Co-authored papers 1
Guoying K Yu
Co-authored papers 1
Release 1.2