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Author Details

Nadeem Moghal
Princess Margaret Cancer Centre, University Health Network
1991
77
25
PMIDPaper TitleJournal TitlePublished Year
36305267The NRF2 antagonist ML385 inhibits PI3K-mTOR signaling and growth of lung squamous cell carcinoma cells.Cancer Med2023
36535627Single-Cell Analysis Reveals Transcriptomic Features of Drug-Tolerant Persisters and Stromal Adaptation in a Patient-Derived EGFR-Mutated Lung Adenocarcinoma Xenograft Model.J Thorac Oncol2023
34648945Lung Cancer Driven by BRAF<sup>G469V</sup> Mutation Is Targetable by EGFR Kinase Inhibitors.J Thorac Oncol2022
35383171Integrative analysis of non-small cell lung cancer patient-derived xenografts identifies distinct proteotypes associated with patient outcomes.Nat Commun2022
34284202Antitumor efficacy of XPO1 inhibitor Selinexor in KRAS-mutant lung adenocarcinoma patient-derived xenografts.Transl Oncol2021
32521388BRAF V600E mutation and MET amplification as resistance pathways of the second-generation anaplastic lymphoma kinase (ALK) inhibitor alectinib in lung cancer.Lung Cancer2020
31694835Organoid Cultures as Preclinical Models of Non-Small Cell Lung Cancer.Clin Cancer Res2020
32447118EGFR-mutated lung adenocarcinomas from patients who progressed on EGFR-inhibitors show high engraftment rates in xenograft models.Lung Cancer2020
32414921Multivalent assembly of KRAS with the RAS-binding and cysteine-rich domains of CRAF on the membrane.Proc Natl Acad Sci U S A2020
30978569Characterization of Distinct Populations of Carcinoma-Associated Fibroblasts from Non-Small Cell Lung Carcinoma Reveals a Role for ST8SIA2 in Cancer Cell Invasion.Neoplasia2019
31455821PIDD interaction with KEAP1 as a new mutation-independent mechanism to promote NRF2 stabilization and chemoresistance in NSCLC.Sci Rep2019
30093452Targeting the CDK4/6-Rb Pathway Enhances Response to PI3K Inhibition in <i>PIK3CA</i>-Mutant Lung Squamous Cell Carcinoma.Clin Cancer Res2018
27750381Molecular heterogeneity of non-small cell lung carcinoma patient-derived xenografts closely reflect their primary tumors.Int J Cancer2017
28794006Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.Mol Cell Proteomics2017
27207389The SWI/SNF chromatin remodeling complex exerts both negative and positive control over LET-23/EGFR-dependent vulval induction in Caenorhabditis elegans.Dev Biol2016
27880766SOX2 and PI3K Cooperate to Induce and Stabilize a Squamous-Committed Stem Cell Injury State during Lung Squamous Cell Carcinoma Pathogenesis.PLoS Biol2016
24496385Allowing patients to choose the ethnicity of attending doctors is institutional racism.BMJ2014
25509489Bold move brings hope for children's services.Health Serv J2014
25551685Cell surface marker profiling of human tracheal basal cells reveals distinct subpopulations, identifies MST1/MSP as a mitogenic signal, and identifies new biomarkers for lung squamous cell carcinomas.Respir Res2014
23319891Neurons refine the Caenorhabditis elegans body plan by directing axial patterning by Wnts.PLoS Biol2013
27293581One good match permits another-why HLA-matched blood transfusion makes sense.Clin Kidney J2013
23697394The GMC can learn from its institutional racism.BMJ2013
23271360Performing renal biopsies in children under general anaesthesia in the lateral position.Pediatr Nephrol2013
22399341Notch signaling in lung development and disease.Adv Exp Med Biol2012
22734077Mission, vision, and values statements in healthcare: what are they for?BMJ2012
22337788I don't need my own office.BMJ2012
21611885Nephrotic syndrome in infancy can spontaneously resolve.Pediatr Nephrol2011
20804964Tumor-initiating cells are rare in many human tumors.Cell Stem Cell2010
18688657Multicentre prospective randomised trial of tacrolimus, azathioprine and prednisolone with or without basiliximab: two-year follow-up data.Pediatr Nephrol2009
19369860The marine alkaloid naamidine A promotes caspase-dependent apoptosis in tumor cells.Anticancer Drugs2009
19121712The fragmented clinical record: a risk to at-risk children.Lancet2009
18424762A novel non-synonymous polymorphism (p.Arg240His) in C4b-binding protein is associated with atypical hemolytic uremic syndrome and leads to impaired alternative pathway cofactor activity.J Immunol2008
18796626Mutations in complement C3 predispose to development of atypical hemolytic uremic syndrome.Blood2008
18254769Histological changes and temperature distribution studies of a novel bipolar radiofrequency heating system in degenerated and nondegenerated human cadaver lumbar discs.Pain Med2008
18305070Furosemide and acute kidney injury in neonates.Arch Dis Child Fetal Neonatal Ed2008
16990369Renovascular hypertension commencing during fetal life.Arch Dis Child Fetal Neonatal Ed2007
17339331An activating mutation in sos-1 identifies its Dbl domain as a critical inhibitor of the epidermal growth factor receptor pathway during Caenorhabditis elegans vulval development.Mol Cell Biol2007
17109135Post streptococcal acute glomerulonephritis secondary to sporadic Streptococcus equi infection.Pediatr Nephrol2007
16252099Tissue plasminogen activator for blocked peritoneal dialysis catheters.Pediatr Nephrol2006
16827869A prospective, randomized, multicenter trial of tacrolimus-based therapy with or without basiliximab in pediatric renal transplantation.Am J Transplant2006
16980384sli-3 negatively regulates the LET-23/epidermal growth factor receptor-mediated vulval induction pathway in Caenorhabditis elegans.Genetics2006
16499601Acute appendicitis occurring immediately post-renal transplant.Pediatr Transplant2006
16491418Is there a role for vincristine in nephrotic syndrome?Pediatr Nephrol2006
16584932Management of acute renal failure in the newborn.Semin Fetal Neonatal Med2006
16369844Childhood membranous nephropathy in association with interstitial nephritis and Fanconi syndrome.Pediatr Nephrol2006
15856312The Alport nephropathy: clinicopathological correlations.Pediatr Nephrol2005
15940547A nephrotic child with deep vein thrombosis after a long-haul flight.Pediatr Nephrol2005
14977711Ibuprofen and acute renal failure in a toddler.Arch Dis Child2004
15575006Cerebral vasculitis in a teenager with Goodpasture's syndrome.Nephrol Dial Transplant2004
12441291A component of the transcriptional mediator complex inhibits RAS-dependent vulval fate specification in C. elegans.Development2003
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Collaborators

Ming-Sound Tsao
University Health Network, University of Toronto
Co-authored papers 17
Nhu-An Pham
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 10
Ming Li
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 8
Vibha Raghavan
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 7
Paul W Sternberg
California Institute of Technology
Co-authored papers 7
Frances A Shepherd
University Health Network, Princess Margaret Cancer Centre
Co-authored papers 7
Geoffrey Liu
The Princess Margaret Cancer Centre/University of Toronto
Co-authored papers 6
Dennis Wang
Sheffield Institute of Translational Neuroscience, University of Sheffield
Co-authored papers 4
Shingo Sakashita
National Cancer Center Exploratory Oncology Research & Clinical Trial Center
Co-authored papers 4
Thomas K Waddell
Toronto General Hospital
Co-authored papers 4
Ni Liu
Princess Margaret Cancer Centre, University Health Network, University of Toronto
Co-authored papers 3
Sharon Lee
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 3
Shaf Keshavjee
University Health Network, University Health Network and University of Toronto
Co-authored papers 2
Michael F Moran
Hospital for Sick Children, University of Toronto
Co-authored papers 2
Jiefei Tong
Hospital for Sick Children
Co-authored papers 2
Laurie Ailles
University of Toronto
Co-authored papers 2
Paul Taylor
Hospital for Sick Children
Co-authored papers 2
Moin A Saleem
Co-authored papers 2
Shirley Tam
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
Chang-Qi Zhu
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
Melania Pintilie
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
Roya Navab
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
Brian Raught
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 1
Arvind Singh Mer
University of Ottawa
Co-authored papers 1
Christine To
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 1
Dan Strumpf
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 1
Thomas Kislinger
Princess Margaret Cancer Centre, University Health Network, University of Toronto
Co-authored papers 1
Sameer Agnihotri
Co-authored papers 1
Igor Jurisica
Schroeder Arthritis Institute
Co-authored papers 1
John D McPherson
Ontario Institute for Cancer Research
Co-authored papers 1
Release 1.2