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Author Details

Peggy Sekula
Institute of Genetic Epidemiology, University of Freiburg
2008
54
23
PMIDPaper TitleJournal TitlePublished Year
36481179A polygenic score for reduced kidney function and adverse outcomes in a cohort with chronic kidney disease.Kidney Int2023
37989062Meta-GWAS on PCSK9 concentrations reveals associations of novel loci outside the PCSK9 locus in White populations.Atherosclerosis2023
35612992Uromodulin and its association with urinary metabolites: the German Chronic Kidney Disease Study.Nephrol Dial Transplant2023
35524694Association of osteopontin with kidney function and kidney failure in chronic kidney disease patients: the GCKD study.Nephrol Dial Transplant2023
37277652Genetic studies of paired metabolomes reveal enzymatic and transport processes at the interface of plasma and urine.Nat Genet2023
34298143A Predictive Model for Progression of CKD to Kidney Failure Based on Routine Laboratory Tests.Am J Kidney Dis2022
35387881PCSK9 and Cardiovascular Disease in Individuals with Moderately Decreased Kidney Function.Clin J Am Soc Nephrol2022
35446786Genome-wide studies reveal factors associated with circulating uromodulin and its relationships to complex diseases.JCI Insight2022
35385482Genetics of osteopontin in patients with chronic kidney disease: The German Chronic Kidney Disease study.PLoS Genet2022
34140400Self-Reported Medication Use and Urinary Drug Metabolites in the German Chronic Kidney Disease (GCKD) Study.J Am Soc Nephrol2021
33738486pgainsim: an R-package to assess the mode of inheritance for quantitative trait loci in GWAS.Bioinformatics2021
33839201Urine Metabolite Levels, Adverse Kidney Outcomes, and Mortality in CKD Patients: A Metabolome-wide Association Study.Am J Kidney Dis2021
34362783The Promise of Metabolomics in Decelerating CKD Progression in Children.Clin J Am Soc Nephrol2021
32353449Incidence of Epidermal Necrolysis: Results of the German Registry.J Invest Dermatol2020
34349984Thyroid function, renal events and mortality in chronic kidney disease patients: the German Chronic Kidney Disease study.Clin Kidney J2020
31959995Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans.Nat Genet2020
32572055Urine 6-Bromotryptophan: Associations with Genetic Variants and Incident End-Stage Kidney Disease.Sci Rep2020
32728058The relationship between blood metabolites of the tryptophan pathway and kidney function: a bidirectional Mendelian randomization analysis.Sci Rep2020
32869749Clinical decision making in small non-functioning VHL-related incidentalomas.Endocr Connect2020
30817158A Novel Metabolic Signature To Predict the Requirement of Dialysis or Renal Transplantation in Patients with Chronic Kidney Disease.J Proteome Res2019
31661010Growth characteristics and therapeutic decision markers in von Hippel-Lindau disease patients with renal cell carcinoma.Orphanet J Rare Dis2019
31822541Design choices for observational studies of the effect of exposure on disease incidence.BMJ Open2019
30972788HLA-B*57:01 confers genetic susceptibility to carbamazepine-induced SJS/TEN in Europeans.Allergy2019
29602398Genome-Wide Association Studies of Metabolite Concentrations (mGWAS): Relevance for Nephrology.Semin Nephrol2018
29499647Control procedures and estimators of the false discovery rate and their application in low-dimensional settings: an empirical investigation.BMC Bioinformatics2018
29545352Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.J Am Soc Nephrol2018
27333618Genetic risk variants for membranous nephropathy: extension of and association with other chronic kidney disease aetiologies.Nephrol Dial Transplant2017
28108296Are Idiopathic Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Related to Drugs in Food? The Example of Phenylbutazone.J Invest Dermatol2017
28360221<i>NFAT5</i> and <i>SLC4A10</i> Loci Associate with Plasma Osmolality.J Am Soc Nephrol2017
28329382Systemic Immunomodulating Therapies for Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Systematic Review and Meta-analysis.JAMA Dermatol2017
29234020From Discovery to Translation: Characterization of C-Mannosyltryptophan and Pseudouridine as Markers of Kidney Function.Sci Rep2017
28614415Did the reporting of prognostic studies of tumour markers improve since the introduction of REMARK guideline? A comparison of reporting in published articles.PLoS One2017
28011147Interleukin-15 Is Associated with Severity and Mortality in Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis.J Invest Dermatol2017
27486138Mendelian Randomization as an Approach to Assess Causality Using Observational Data.J Am Soc Nephrol2016
26449609A Metabolome-Wide Association Study of Kidney Function and Disease in the General Population.J Am Soc Nephrol2016
27531721Assessment of the extent of unpublished studies in prognostic factor research: a systematic review of p53 immunohistochemistry in bladder cancer as an example.BMJ Open2016
27549803The case-crossover design via penalized regression.BMC Med Res Methodol2016
23955072Generalized pustular eruptions: time to adapt the disease taxonomy to the genetic architecture?J Invest Dermatol2014
24322785HLA-A*31:01 and different types of carbamazepine-induced severe cutaneous adverse reactions: an international study and meta-analysis.Pharmacogenomics J2014
24401562Assessment of the "case-chaos" design as an adjunct to the case-control design.Am J Epidemiol2014
23358093Rare variations in IL36RN in severe adverse drug reactions manifesting as acute generalized exanthematous pustulosis.J Invest Dermatol2013
23855313Drug reaction with eosinophilia and systemic symptoms (DRESS): an original multisystem adverse drug reaction. Results from the prospective RegiSCAR study.Br J Dermatol2013
23743649Lack of a specific humoral autoreactivity in sera from patients with early erythema exsudativum multiforme majus.J Invest Dermatol2013
23739151Metabolites associate with kidney function decline and incident chronic kidney disease in the general population.Nephrol Dial Transplant2013
23389396Comprehensive survival analysis of a cohort of patients with Stevens-Johnson syndrome and toxic epidermal necrolysis.J Invest Dermatol2013
23413807Prognosis of generalized bullous fixed drug eruption: comparison with Stevens-Johnson syndrome and toxic epidermal necrolysis.Br J Dermatol2013
22639874The role of prior corticosteroid use on the clinical course of Stevens-Johnson syndrome and toxic epidermal necrolysis: a case-control analysis of patients selected from the multinational EuroSCAR and RegiSCAR studies.Br J Dermatol2012
22464876Serum metabolite concentrations and decreased GFR in the general population.Am J Kidney Dis2012
21228709Evaluation of SCORTEN on a cohort of patients with Stevens-Johnson syndrome and toxic epidermal necrolysis included in the RegiSCAR study.J Burn Care Res2011
21801394Genome-wide association study of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Europe.Orphanet J Rare Dis2011
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Collaborators

Anna K??ttgen
Institute of Genetic Epidemiology, Medical Center-University of Freiburg
Co-authored papers 22
Kai-Uwe Eckardt
Co-authored papers 17
Peter J Oefner
Institute of Functional Genomics, University of Regensburg
Co-authored papers 10
Florian Kronenberg
Co-authored papers 9
Matthias Wuttke
Co-authored papers 7
Christian Gieger
German Research Center for Cardiovascular Disease (DZHK)
Co-authored papers 6
Morgan E Grams
New York University Grossman School of Medicine
Co-authored papers 5
Matthias Nauck
University Medicine Greifswald
Co-authored papers 5
Josef Coresh
Co-authored papers 5
Christa Meisinger
University Hospital Augsburg
Co-authored papers 4
Eric Boerwinkle
Baylor College of Medicine
Co-authored papers 4
Claudia Lamina
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Annette Peters
Ludwig-Maximilians-Universitat Munchen
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Thomas Illig
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Olivier Devuyst
Institute of Physiology, University of Zurich, Cliniques Universitaires Saint-Luc
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Michael A Simpson
King's College London
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Uwe V??lker
University Medicine
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Richard C Trembath
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Marcus E Kleber
Heidelberg University
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Angela Döring
Co-authored papers 2
Barbara Kollerits
Co-authored papers 2
Cristian Pattaro
Institute for Biomedicine (Affiliated to the University of Lubeck)
Co-authored papers 2
Terho Lehtim??ki
Finnish Cardiovascular Research Center-Tampere - FCRCT, Tampere University
Co-authored papers 2
Shreeram Akilesh
Co-authored papers 2
Michael Altenbuchinger
University Medical Center Gottingen
Co-authored papers 2
Winfried M??rz
Medical Clinic V, University of Heidelberg
Co-authored papers 2
Martin H de Borst
University Medical Center Groningen
Co-authored papers 1
Mitchell H Gail
Co-authored papers 1
Andrew B Singleton
National Institute on Aging
Co-authored papers 1
Gary S Collins
University of Oxford
Co-authored papers 1
Release 1.2