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Author Details

Jeffrey L Wrana
Lunenfeld-Tanenbaum Research Institute Mount Sinai Hospital
1985
284
102
PMIDPaper TitleJournal TitlePublished Year
34706787Hospital outbreak of the severe acute respiratory coronavirus virus 2 (SARS-CoV-2) delta variant in partially and fully vaccinated patients and healthcare workers in Toronto, Canada.Infect Control Hosp Epidemiol2023
37540756Adseverin, an actin-binding protein, modulates hypertrophic chondrocyte differentiation and osteoarthritis progression.Sci Adv2023
35611490Regulation of homeostasis and regeneration in the adult intestinal epithelium by the TGF-β superfamily.Dev Dyn2023
37258521In vivo CRISPR screens reveal Serpinb9 and Adam2 as regulators of immune therapy response in lung cancer.Nat Commun2023
36945493Integrated single-cell analysis defines the epigenetic basis of castration-resistant prostate luminal cells.bioRxiv2023
37162959p53 promotes revival stem cells in the regenerating intestine after severe radiation injury.bioRxiv2023
36640358Absolute scaling of single-cell transcriptomes identifies pervasive hypertranscription in adult stem and progenitor cells.Cell Rep2023
34727519Enteric glial cell heterogeneity regulates intestinal stem cell niches.Cell Stem Cell2022
35437520Immunogenicity of convalescent and vaccinated sera against clinical isolates of ancestral SARS-CoV-2, Beta, Delta, and Omicron variants.Med2022
35356067A scalable serology solution for profiling humoral immune responses to SARS-CoV-2 infection and vaccination.Clin Transl Immunology2022
36002557Translational feasibility and efficacy of nasal photodynamic disinfection of SARS-CoV-2.Sci Rep2022
36108220Loss of Epigenetic Regulation Disrupts Lineage Integrity, Induces Aberrant Alveogenesis, and Promotes Breast Cancer.Cancer Discov2022
35939622A single cell survey of the microbial impacts on the mouse small intestinal epithelium.Gut Microbes2022
35914530Systematic exploration of dynamic splicing networks reveals conserved multistage regulators of neurogenesis.Mol Cell2022
35320001NUAK1 promotes organ fibrosis via YAP and TGF-β/SMAD signaling.Sci Transl Med2022
35191398Myofibroblast YAP/TAZ activation is a key step in organ fibrogenesis.JCI Insight2022
35183479A specialist-generalist framework for epithelial-mesenchymal plasticity in cancer.Trends Cancer2022
32917504Overexpression of the Severe Acute Respiratory Syndrome Coronavirus-2 Receptor, Angiotensin-Converting Enzyme 2, in Diabetic Kidney Disease: Implications for Kidney Injury in Novel Coronavirus Disease 2019.Can J Diabetes2021
33526784A glucose meter interface for point-of-care gene circuit-based diagnostics.Nat Commun2021
33831275The hippo pathway: A master regulator of liver metabolism, regeneration, and disease.FASEB J2021
33658502A multiplexed, next generation sequencing platform for high-throughput detection of SARS-CoV-2.Nat Commun2021
34861187Sugar defeats the Hippo: Glycogen regulation of the Hippo pathway in liver.Mol Cell2021
34528691YAP establishes epiblast responsiveness to inductive signals for germ cell fate.Development2021
34716314Somatic driver mutation prevalence in 1844 prostate cancers identifies ZNRF3 loss as a predictor of metastatic relapse.Nat Commun2021
34270926Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity.Cancer Cell2021
34001180Comparison of SARS-CoV-2 indirect and direct RT-qPCR detection methods.Virol J2021
33234594An endogenous PI3K interactome promoting astrocyte-mediated neuroprotection identifies a novel association with RNA-binding protein ZC3H14.J Biol Chem2021
32444641TNFAIP8 controls murine intestinal stem cell homeostasis and regeneration by regulating microbiome-induced Akt signaling.Nat Commun2020
33033173Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients.Sci Immunol2020
33298874A novel negative regulatory mechanism of Smurf2 in BMP/Smad signaling in bone.Bone Res2020
32798968Modeling the Control of TGF-β/Smad Nuclear Accumulation by the Hippo Pathway Effectors, Taz/Yap.iScience2020
32572160Functional genomics identifies new synergistic therapies for retinoblastoma.Oncogene2020
32778845Functional characterization of a PROTAC directed against BRAF mutant V600E.Nat Chem Biol2020
31019301Single-cell transcriptomes of the regenerating intestine reveal a revival stem cell.Nature2019
31306665Gaining Insights into the Function of Post-Translational Protein Modification Using Genome Engineering and Molecular Cell Biology.J Mol Biol2019
30898844Cell competition during reprogramming gives rise to dominant clones.Science2019
31142743Atypical function of a centrosomal module in WNT signalling drives contextual cancer cell motility.Nat Commun2019
27657886Regulation of Rho GTPases from the lateral sides of migrating cells.Small GTPases2018
30158528A feed forward loop enforces YAP/TAZ signaling during tumorigenesis.Nat Commun2018
29934521The E3 ubiquitin ligase SMURF1 regulates cell-fate specification and outflow tract septation during mammalian heart development.Sci Rep2018
29934496Pulmonary pericytes regulate lung morphogenesis.Nat Commun2018
30121256DNA Methylation Reduces the Yes-Associated Protein 1/WW Domain Containing Transcription Regulator 1 Pathway and Prevents Pathologic Remodeling during Bladder Obstruction by Limiting Expression of BDNF.Am J Pathol2018
29874582Crucial Role of Postsynaptic Syntaxin 4 in Mediating Basal Neurotransmission and Synaptic Plasticity in Hippocampal CA1 Neurons.Cell Rep2018
27720985KATapulting toward Pluripotency and Cancer.J Mol Biol2017
28108485TGF-β Family Signaling in Embryonic and Somatic Stem-Cell Renewal and Differentiation.Cold Spring Harb Perspect Biol2017
28188528LUMIER: A Discovery Tool for Mammalian Protein Interaction Networks.Methods Mol Biol2017
28157508Multilayered Control of Alternative Splicing Regulatory Networks by Transcription Factors.Mol Cell2017
28649369Recent advances in understanding contextual TGFβ signaling.F1000Res2017
28527754Hippo signalling in intestinal regeneration and cancer.Curr Opin Cell Biol2017
28683327Exosomes Mediate Mobilization of Autocrine Wnt10b to Promote Axonal Regeneration in the Injured CNS.Cell Rep2017
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Collaborators

University of Perugia
Co-authored papers 34
Princess Margaret Cancer Centre
Co-authored papers 19
Co-authored papers 17
Princess Margaret Cancer Centre
Co-authored papers 16
Princess Margaret Cancer Centre
Co-authored papers 14
University of Toronto
Co-authored papers 11
University of Toronto
Co-authored papers 11
Co-authored papers 11
Lunenfeld-Tanenbaum Research Institute
Co-authored papers 9
University of Toronto
Co-authored papers 9
University of British Columbia
Co-authored papers 7
Ontario Institute for Cancer Research, University Avenue
Co-authored papers 6
Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, University Avenue R988
Co-authored papers 6
Helen Diller Family Cancer Center, University of California San Francisco
Co-authored papers 6
Hangzhou City University
Co-authored papers 6
Mount Sinai Health System and University Health Network
Co-authored papers 5
Ontario Institute for Cancer Research, University Avenue
Co-authored papers 5
College of Medicine, University of Saskatchewan
Co-authored papers 5
University of Toronto
Co-authored papers 5
Hospital for Sick Children
Co-authored papers 5
College Street, University of Toronto
Co-authored papers 5
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 4
The Hospital for Sick Children
Co-authored papers 4
The Hospital for Sick Children, University Avenue
Co-authored papers 3
University of California Los Angeles
Co-authored papers 3
The Lunenfeld-Tannenbaum Research Institute, Mount Sinai Hospital
Co-authored papers 3
Co-authored papers 3
Schroeder Arthritis Institute
Co-authored papers 3
Air Quality Modelling and Integration Research Unit
Co-authored papers 3
McGill University
Co-authored papers 3