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Author Details

Michael F Moran
Hospital for Sick Children, University of Toronto
1985
125
44
PMIDPaper TitleJournal TitlePublished Year
36214668Mitochondrial Aconitase ACO2 Links Iron Homeostasis with Tumorigenicity in Non-Small Cell Lung Cancer.Mol Cancer Res2023
37855416Activation of mitogen-activated protein kinase signaling and development of papillary thyroid carcinoma in thyroid-stimulating hormone receptor D633H knockin mice.Eur Thyroid J2023
38052158Activation of mitogen-activated protein kinase signaling and development of papillary thyroid carcinoma in thyroid-stimulating hormone receptor D633H knockin mice.Eur Thyroid J2023
37028761The ubiquitin ligase HERC4 suppresses MafA transcriptional activity triggered by GSK3β in myeloma by atypical K63-linked polyubiquitination.J Biol Chem2023
36070144Oncohistone interactome profiling uncovers contrasting oncogenic mechanisms and identifies potential therapeutic targets in high grade glioma.Acta Neuropathol2022
35383171Integrative analysis of non-small cell lung cancer patient-derived xenografts identifies distinct proteotypes associated with patient outcomes.Nat Commun2022
35739422Author Correction: Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome.Nat Cancer2022
35613471Engineered SH2 Domains for Targeted Phosphoproteomics.ACS Chem Biol2022
35422502Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome.Nat Cancer2022
35362478Tankyrase represses autoinflammation through the attenuation of TLR2 signaling.J Clin Invest2022
35595168Proteomic Characterization of a Candidate Polygenic Driver of Metabolism in Non-small Cell Lung Cancer.J Mol Biol2022
32842143Targeting the Otub1/c-Maf axis for the treatment of multiple myeloma.Blood2021
33617900SLAP2 Adaptor Binding Disrupts c-CBL Autoinhibition to Activate Ubiquitin Ligase Function.J Mol Biol2021
34680183Reinspection of a Clinical Proteomics Tumor Analysis Consortium (CPTAC) Dataset with Cloud Computing Reveals Abundant Post-Translational Modifications and Protein Sequence Variants.Cancers (Basel)2021
32539411Data Dependent-Independent Acquisition (DDIA) Proteomics.J Proteome Res2020
32094923A drug discovery platform to identify compounds that inhibit EGFR triple mutants.Nat Chem Biol2020
32009416Repeat-Preserving Decoy Database for False Discovery Rate Estimation in Peptide Identification.J Proteome Res2020
31822558The deubiquitinase USP7 stabilizes Maf proteins to promote myeloma cell survival.J Biol Chem2020
32903271Cancer proteome and metabolite changes linked to SHMT2.PLoS One2020
30431205Engineered SH2 domains with tailored specificities and enhanced affinities for phosphoproteome analysis.Protein Sci2019
31330989Somatic Alteration Burden Involving Non-Cancer Genes Predicts Prognosis in Early-Stage Non-Small Cell Lung Cancer.Cancers (Basel)2019
31292163ID1 Is Critical for Tumorigenesis and Regulates Chemoresistance in Glioblastoma.Cancer Res2019
31249099Prediction of LC-MS/MS Properties of Peptides from Sequence by Deep Learning.Mol Cell Proteomics2019
30713027Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15.Structure2019
30938160Evosep One Enables Robust Deep Proteome Coverage Using Tandem Mass Tags while Significantly Reducing Instrument Time.J Proteome Res2019
30417091A tyrosine sulfation-dependent HLA-I modification identifies memory B cells and plasma cells.Sci Adv2018
30158528A feed forward loop enforces YAP/TAZ signaling during tumorigenesis.Nat Commun2018
30212448Refined RIP-seq protocol for epitranscriptome analysis with low input materials.PLoS Biol2018
30297534Pathologic Oxidation of PTPN12 Underlies ABL1 Phosphorylation in Hereditary Leiomyomatosis and Renal Cell Carcinoma.Cancer Res2018
27593927Cellular stress induces TRB3/USP9x-dependent Notch activation in cancer.Oncogene2017
28285997CCM-3 Promotes C. elegans Germline Development by Regulating Vesicle Trafficking Cytokinesis and Polarity.Curr Biol2017
28176486Integrated analysis of proteome, phosphotyrosine-proteome, tyrosine-kinome, and tyrosine-phosphatome in acute myeloid leukemia.Proteomics2017
28933784Inhibition of the deubiquitinase USP5 leads to c-Maf protein degradation and myeloma cell apoptosis.Cell Death Dis2017
28673317The ubiquitin-conjugating enzyme UBE2O modulates c-Maf stability and induces myeloma cell apoptosis.J Hematol Oncol2017
28877995A neuroprotective agent that inactivates prodegenerative TrkA and preserves mitochondria.J Cell Biol2017
28894103The Candida albicans transcription factor Cas5 couples stress responses, drug resistance and cell cycle regulation.Nat Commun2017
27880036Protein-phosphotyrosine proteome profiling by superbinder-SH2 domain affinity purification mass spectrometry, sSH2-AP-MS.Proteomics2017
27750381Molecular heterogeneity of non-small cell lung carcinoma patient-derived xenografts closely reflect their primary tumors.Int J Cancer2017
26825710The ubiquitin ligase HERC4 mediates c-Maf ubiquitination and delays the growth of multiple myeloma xenografts in nude mice.Blood2016
27797343Reciprocal stabilization of ABL and TAZ regulates osteoblastogenesis through transcription factor RUNX2.J Clin Invest2016
27152361Identification of human plasma cells with a lamprey monoclonal antibody.JCI Insight2016
25403733Comprehensive identification of phosphorylation sites on the Numb endocytic adaptor protein.Proteomics2015
26237434Distinct Regulation of Transmitter Release at the Drosophila NMJ by Different Isoforms of nemy.PLoS One2015
25721092Comprehensive proteome analysis of fresh frozen and optimal cutting temperature (OCT) embedded primary non-small cell lung carcinoma by LC-MS/MS.Methods2015
25784717CHCHD2 Is Coamplified with EGFR in NSCLC and Regulates Mitochondrial Function and Cell Migration.Mol Cancer Res2015
25588725Signal transduction.Proteomics2015
25587033Tyrosine phosphorylation of the Lyn Src homology 2 (SH2) domain modulates its binding affinity and specificity.Mol Cell Proteomics2015
25311528Differential regulation of FGFR3 by PTPN1 and PTPN2.Proteomics2015
25330774The major cystic fibrosis causing mutation exhibits defective propensity for phosphorylation.Proteomics2015
24453208Proteomic profiles of human lung adeno and squamous cell carcinoma using super-SILAC and label-free quantification approaches.Proteomics2014
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Collaborators

Jiefei Tong
Hospital for Sick Children
Co-authored papers 42
Paul Taylor
Hospital for Sick Children
Co-authored papers 40
Ming-Sound Tsao
University Health Network, University of Toronto
Co-authored papers 17
Tony Pawson
Co-authored papers 12
Nhu-An Pham
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 10
Thomas Kislinger
Princess Margaret Cancer Centre, University Health Network, University of Toronto
Co-authored papers 9
Frances A Shepherd
University Health Network, Princess Margaret Cancer Centre
Co-authored papers 7
Geoffrey Liu
The Princess Margaret Cancer Centre/University of Toronto
Co-authored papers 7
Vladimir Ignatchenko
Margaret Cancer Center
Co-authored papers 6
Suzanne Trudel
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 6
Brian Raught
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 5
Shingo Sakashita
National Cancer Center Exploratory Oncology Research & Clinical Trial Center
Co-authored papers 5
Ming Li
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 5
Yuhong Wei
Rosalind and Morris Goodman Cancer Institute, McGill University
Co-authored papers 5
Sachdev S Sidhu
School of Pharmacy, University of Waterloo
Co-authored papers 5
Jason Moffat
University of Toronto
Co-authored papers 5
Lei Li
Hospital for Sick Children
Co-authored papers 4
Wen Zhang
Nanjing Agricultural University
Co-authored papers 4
Melania Pintilie
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 4
Cynthia Hawkins
The Hospital for Sick Children
Co-authored papers 3
Daniela Rotin
The Hospital for Sick Children
Co-authored papers 3
Mike Tyers
Institute for Research in Immunology and Cancer (IRIC), Universite de Montreal
Co-authored papers 3
Naoki Yanagawa
Yamagata Prefectural Central Hospital
Co-authored papers 3
Frank McCormick
Frederick National Laboratory for Cancer Research
Co-authored papers 3
Ivan Sadowski
University of British Columbia
Co-authored papers 3
Sameer Agnihotri
Co-authored papers 3
Dennis Wang
Sheffield Institute of Translational Neuroscience, University of Sheffield
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Chang-Qi Zhu
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Release 1.2