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Author Details

John T Poirier
Laura and Isaac Perlmutter Cancer Center
2007
88
42
PMIDPaper TitleJournal TitlePublished Year
36525973KMT2D deficiency drives lung squamous cell carcinoma and hypersensitivity to RTK-RAS inhibition.Cancer Cell2023
37425844Glutamine antagonist DRP-104 suppresses tumor growth and enhances response to checkpoint blockade in <i>KEAP1</i> mutant lung cancer.bioRxiv2023
37210008Clinical Benefit From Immunotherapy in Patients With SCLC Is Associated With Tumor Capacity for Antigen Presentation.J Thorac Oncol2023
37131623<i>In vivo</i> metabolomics identifies CD38 as an emergent vulnerability in <i>LKB1</i> -mutant lung cancer.bioRxiv2023
34815254Inhibition of XPO1 Sensitizes Small Cell Lung Cancer to First- and Second-Line Chemotherapy.Cancer Res2022
35440124Genomic and transcriptomic analysis of a library of small cell lung cancer patient-derived xenografts.Nat Commun2022
35759660Delta-like ligand 3-targeted radioimmunotherapy for neuroendocrine prostate cancer.Proc Natl Acad Sci U S A2022
35941262cfDNA methylome profiling for detection and subtyping of small cell lung cancers.Nat Cancer2022
36313536Protocol to dissociate, process, and analyze the human lung tissue using single-cell RNA-seq.STAR Protoc2022
35931202Generation of hepatoma cell lines deficient in microsomal triglyceride transfer protein.J Lipid Res2022
36380343Genomic and transcriptomic analysis of a diffuse pleural mesothelioma patient-derived xenograft library.Genome Med2022
35046060Radioimmunotherapy Targeting Delta-like Ligand 3 in Small Cell Lung Cancer Exhibits Antitumor Efficacy with Low Toxicity.Clin Cancer Res2022
35058323Molecular Imaging of Neuroendocrine Prostate Cancer by Targeting Delta-Like Ligand 3.J Nucl Med2022
33382968Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks.Cell2021
33547247Correction: Combined Inhibition of NEDD8-activating Enzyme and mTOR Suppresses NF2 Loss-driven Tumorigenesis.Mol Cancer Ther2021
33924774N-Linked Glycosylation on Anthrax Toxin Receptor 1 Is Essential for Seneca Valley Virus Infection.Viruses2021
33835770Synthesis and Comparative <i>In Vivo</i> Evaluation of Site-Specifically Labeled Radioimmunoconjugates for DLL3-Targeted ImmunoPET.Bioconjug Chem2021
34648371Replication and single-cycle delivery of SARS-CoV-2 replicons.Science2021
34462284Targeting the Atf7ip-Setdb1 Complex Augments Antitumor Immunity by Boosting Tumor Immunogenicity.Cancer Immunol Res2021
34653364Signatures of plasticity, metastasis, and immunosuppression in an atlas of human small cell lung cancer.Cancer Cell2021
34712921MAPK pathway activation selectively inhibits ASCL1-driven small cell lung cancer.iScience2021
34834920A CRISPR Activation Screen Identifies an Atypical Rho GTPase That Enhances Zika Viral Entry.Viruses2021
34344693Rlf-Mycl Gene Fusion Drives Tumorigenesis and Metastasis in a Mouse Model of Small Cell Lung Cancer.Cancer Discov2021
34115989Tim-4[+] cavity-resident macrophages impair anti-tumor CD8[+] T cell immunity.Cancer Cell2021
34142094ULK1 inhibition overcomes compromised antigen presentation and restores antitumor immunity in LKB1 mutant lung cancer.Nat Cancer2021
33338421TMEM41B Is a Pan-flavivirus Host Factor.Cell2021
32213539HER2-Mediated Internalization of Cytotoxic Agents in <i>ERBB2</i> Amplified or Mutant Lung Cancers.Cancer Discov2020
32018053New Approaches to SCLC Therapy: From the Laboratory to the Clinic.J Thorac Oncol2020
32042191Regenerative lineages and immune-mediated pruning in lung cancer metastasis.Nat Med2020
33345196Direct genome editing of patient-derived xenografts using CRISPR-Cas9 enables rapid <i>in vivo</i> functional genomics.Nat Cancer2020
33052348TMEM41B is a pan-flavivirus host factor.bioRxiv2020
33052332Genome-scale identification of SARS-CoV-2 and pan-coronavirus host factor networks.bioRxiv2020
33264619Concurrent Mutations in STK11 and KEAP1 Promote Ferroptosis Protection and SCD1 Dependence in Lung Cancer.Cell Rep2020
32599072Role of mTOR As an Essential Kinase in SCLC.J Thorac Oncol2020
32707077Emergence of a High-Plasticity Cell State during Lung Cancer Evolution.Cancer Cell2020
32646968Epigenetic CRISPR Screens Identify <i>Npm1</i> as a Therapeutic Vulnerability in Non-Small Cell Lung Cancer.Cancer Res2020
32185149Virus-Receptor Interactions and Virus Neutralization: Insights for Oncolytic Virus Development.Oncolytic Virother2020
30457978Peptide-based PET quantifies target engagement of PD-L1 therapeutics.J Clin Invest2019
31754615Virus-Receptor Interactions: Structural Insights For Oncolytic Virus Development.Oncolytic Virother2019
31300474Integrative Genomic Characterization Identifies Molecular Subtypes of Lung Carcinoids.Cancer Res2019
31300452Circulating Tumor DNA Profiling in Small-Cell Lung Cancer Identifies Potentially Targetable Alterations.Clin Cancer Res2019
31175338Author Correction: Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data.Nat Rev Cancer2019
31375684MYC paralog-dependent apoptotic priming orchestrates a spectrum of vulnerabilities in small cell lung cancer.Nat Commun2019
31195178Positron-Emission Tomographic Imaging of a Fluorine 18-Radiolabeled Poly(ADP-Ribose) Polymerase 1 Inhibitor Monitors the Therapeutic Efficacy of Talazoparib in SCLC Patient-Derived Xenografts.J Thorac Oncol2019
30926931Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data.Nat Rev Cancer2019
31128476A rapid bead-based radioligand binding assay for the determination of target-binding fraction and quality control of radiopharmaceuticals.Nucl Med Biol2019
30831205Acquired BRAF Rearrangements Induce Secondary Resistance to EGFR therapy in EGFR-Mutated Lung Cancers.J Thorac Oncol2019
30723171Targeting NOTCH activation in small cell lung cancer through LSD1 inhibition.Sci Signal2019
30655535ONECUT2 is a driver of neuroendocrine prostate cancer.Nat Commun2019
29330466Target engagement imaging of PARP inhibitors in small-cell lung cancer.Nat Commun2018
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Collaborators

Charles M Rudin
Memorial Sloan Kettering Cancer Center
Co-authored papers 70
Elisa de Stanchina
Co-authored papers 19
Pierre P Massion
Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center
Co-authored papers 7
Charles M Rice
Rockefeller University
Co-authored papers 6
Hans-Heinrich Hoffmann
The Rockefeller University
Co-authored papers 6
Julien Sage
Department of Pediatrics Stanford University Stanford California USA.
Co-authored papers 6
Andrew Chow
Co-authored papers 6
John D Minna
University of Texas Southwestern Medical Center at Dallas
Co-authored papers 5
Trudy G Oliver
Duke University
Co-authored papers 5
Travis J Hollmann
Memorial Sloan Kettering Cancer Center
Co-authored papers 4
Umesh Bhanot
Memorial Sloan Kettering Cancer Center
Co-authored papers 4
Ronglai Shen
Co-authored papers 3
Marc Ladanyi
Memorial Sloan Kettering Cancer Center
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Ramaswamy Govindan
Siteman Cancer Center, Washington University School of Medicine
Co-authored papers 3
Dana Pe'er
Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center
Co-authored papers 3
Tyler Jacks
Co-authored papers 3
Michael J Morris
Memorial Sloan Kettering Cancer Center
Co-authored papers 2
Jorge A Gutierrez
Case Western Reverse University School of Medicine
Co-authored papers 2
Fiona Blackhall
The University of Manchester
Co-authored papers 2
Alexander Drilon
Memorial Sloan Kettering Cancer Center
Co-authored papers 2
Nicholas D Socci
Co-authored papers 2
Martin L Sos
University of Cologne, Faculty of Medicine and University Hospital Cologne
Co-authored papers 2
Nabeel Bardeesy
Massachusetts General Hospital
Co-authored papers 2
Michael F Berger
Co-authored papers 2
Matthias A Karajannis
Co-authored papers 2
Jorge S Reis-Filho
Memorial Sloan-Kettering Cancer Center
Co-authored papers 1
Pasi A J??nne
Dana-Farber Cancer Institute
Co-authored papers 1
Sandra Cristea
Stanford University
Co-authored papers 1
Housheng Hansen He
Princess Margaret Cancer Center, University Health Network, University of Toronto
Co-authored papers 1
Craig H Mermel
Co-authored papers 1
Release 1.2