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Author Details

Dimiter S Dimitrov
1981
346
74
PMIDPaper TitleJournal TitlePublished Year
36917886Fully human monoclonal antibody targeting activated ADAM10 on colorectal cancer cells.Biomed Pharmacother2023
38019654Engineering CD276/B7-H3-targeted antibody-drug conjugates with enhanced cancer-eradicating capability.Cell Rep2023
37700833Editorial: Therapeutic antibody domains against cancer.2023
37774704Preclinical development of a chimeric antigen receptor T cell therapy targeting FGFR4 in rhabdomyosarcoma.Cell Rep Med2023
37771390Preclinical assessment of a novel human antibody VH domain targeting mesothelin as an antibody-drug conjugate.Mol Ther Oncolytics2023
36761762Human antibodies targeting ENPP1 as candidate therapeutics for cancers.Front Immunol2023
37265667Rapid Emergence of Potentially Transmissible Severe Acute Respiratory Syndrome Coronavirus 2 With Resistance to Combination Monoclonal Antibody Therapy.2023
37067377Human Antibody V Domains Targeting GPNMB and VCAM-1 as Candidate Therapeutics for Cancers.2023
36864545Development of an efficient method for selection of stable cell pools for protein expression and surface display with Expi293F cells.2023
36862515COVID-19 convalescent plasma boosts early antibody titer and does not influence the adaptive immune response.JCI Insight2023
36923424Chimeric antigen receptor-T cells are effective against CEACAM5 expressing non-small cell lung cancer cells resistant to antibody-drug conjugates.2023
34582565Adcitmer , a new CD56-targeting monomethyl auristatin E-conjugated antibody, is a potential therapeutic approach in Merkel cell carcinoma.British Journal of Dermatology2022
35464476Construction of a Large Size Human Immunoglobulin Heavy Chain Variable (VH) Domain Library, Isolation and Characterization of Novel Human Antibody VH Domains Targeting PD-L1 and CD22.Frontiers in Immunology2022
36345941In vivo killing of primary HIV-infected cells by peripheral-injected early memory-enriched anti-HIV duoCAR T cells.JCI Insight2022
35877472FGFR4-Targeted Chimeric Antigen Receptors Combined with Anti-Myeloid Polypharmacy Effectively Treat Orthotopic Rhabdomyosarcoma.Mol Cancer Ther2022
35875685Potent and broad neutralization of SARS-CoV-2 variants of concern (VOCs) including omicron sub-lineages BA.1 and BA.2 by biparatopic human VH domains.iScience2022
35482198Yeast Mating as a Tool for Highly Effective Discovery and Engineering of Antibodies via Display Methodologies.Methods in Molecular Biology2022
35982054SARS-CoV-2 variants of concern: spike protein mutational analysis and epitope for broad neutralization.Nature Communications2022
36400786Cancer cell survival depends on collagen uptake into tumor-associated stroma.Nature Communications2022
35399718An insulin growth factor-I/II-neutralizing monoclonal antibody in combination with epidermal growth factor receptor inhibitors potently inhibits tumor cell growth.Journal of Cancer2022
36460335GPC2 antibody-drug conjugate reprograms the neuroblastoma immune milieu to enhance macrophage-driven therapies.J Immunother Cancer2022
34740610A highly-specific fully-human antibody and CAR-T cells targeting CD66e/CEACAM5 are cytotoxic for CD66e-expressing cancer cells in vitro and in vivo.Cancer Lett2022
35272105Functional reconstitution of the MERS CoV receptor binding motif.Molecular Immunology2022
34971569GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity.Cancer Cell2022
35194603Potent Neutralization of Omicron and other SARS-CoV-2 Variants of Concern by Biparatopic Human VH Domains.bioRxiv2022
35174992Design of a Novel Fab-Like Antibody Fragment with Enhanced Stability and Affinity for Clinical use.Small Methods2022
35136050Structural and biochemical rationale for enhanced spike protein fitness in delta and kappa SARS-CoV-2 variants.Nature Communications2022
34768098Inhibitory monoclonal antibody targeting ADAM17 expressed on cancer cells.Translational Oncology2022
34601396Effective killing of cells expressing CD276 (B7-H3) by a bispecific T cell engager based on a new fully human antibody.Translational Oncology2021
34021002Proteomic Screens for Suppressors of Anoikis Identify IL1RAP as a Promising Surface Target in Ewing Sarcoma.Cancer Discov2021
33914735Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies.PLoS Biology2021
34273351Structural details of monoclonal antibody m971 recognition of the membrane-proximal domain of CD22.Journal of Biological Chemistry2021
34107549The reduced form of the antibody CH2 domain.Protein Sci2021
34095859Protocol for constructing large size human antibody heavy chain variable domain (V) library and selection of SARS-CoV-2 neutralizing antibody domains.STAR Protocols2021
33762438Trispecific CD19-CD20-CD22-targeting duoCAR-T cells eliminate antigen-heterogeneous B cell tumors in preclinical models.Science Translational Medicine2021
34337560A GPC2 antibody-drug conjugate is efficacious against neuroblastoma and small-cell lung cancer via binding a conformational epitope.Cell Rep Med2021
33203700Folate Receptor Beta Designates Immunosuppressive Tumor-Associated Myeloid Cells That Can Be Reprogrammed with Folate-Targeted Drugs.Cancer Res2021
33325681Developability Assessment of an Isolated C2 Immunoglobulin Domain.Analytical Chemistry2021
34681796Human Antibody Domains and Fragments Targeting Neutrophil Elastase as Candidate Therapeutics for Cancer and Inflammation-Related Diseases.International Journal of Molecular Sciences2021
34465595Antibody-Drug Conjugate Efficacy in Neuroblastoma: Role of Payload, Resistance Mechanisms, Target Density, and Antibody Internalization.Molecular Cancer Therapeutics2021
34914928Structural analysis of receptor binding domain mutations in SARS-CoV-2 variants of concern that modulate ACE2 and antibody binding.Cell Reports2021
34732890Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs.Nature2021
32941803High Potency of a Bivalent Human V<sub>H</sub> Domain in SARS-CoV-2 Animal Models.Cell2020
32027842Safety, tolerability, pharmacokinetics, and immunogenicity of a human monoclonal antibody targeting the G glycoprotein of henipaviruses in healthy adults: a first-in-human, randomised, controlled, phase 1 study.Lancet Infectious Diseases, The2020
31795802An engineered human IgG1 CH2 domain with decreased aggregation and nonspecific binding.mAbs2020
32544372Potent neutralization of SARS-CoV-2 by human antibody heavy-chain variable domains isolated from a large library with a new stable scaffold.MAbs2020
32591411Interaction with CD68 and Regulation of GAS6 Expression by Endosialin in Fibroblasts Drives Recruitment and Polarization of Macrophages in Hepatocellular Carcinoma.Cancer Research2020
33139569Rapid identification of a human antibody with high prophylactic and therapeutic efficacy in three animal models of SARS-CoV-2 infection.Proc Natl Acad Sci U S A2020
32860752Hematopoietic Progenitor Kinase1 (HPK1) Mediates T Cell Dysfunction and Is a Druggable Target for T Cell-Based Immunotherapies.Cancer Cell2020
32908002Enhancing KDM5A and TLR activity improves the response to immune checkpoint blockade.Sci Transl Med2020
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