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Author Details

Christopher J Howlett
Western University
1999
44
16
PMIDPaper TitleJournal TitlePublished Year
37408614The effect of HLA-DRB1*04:01 on a mouse model of atherosclerosis.J Transl Autoimmun2023
37483495Molecular profiling of solid tumors by next-generation sequencing: an experience from a clinical laboratory.Front Oncol2023
34713980Reducing cytogenetic testing in the era of next generation sequencing: Are we choosing wisely?Int J Lab Hematol2022
35393334Practice guidelines for <i>BRCA1/2</i> tumour testing in ovarian cancer.J Med Genet2022
36442320Immune-based classification of HPV-associated oropharyngeal cancer with implications for biomarker-driven treatment de-intensification.EBioMedicine2022
36307522Dysregulated transforming growth factor-beta mediates early bone marrow dysfunction in diabetes.Commun Biol2022
36380468T-cell clonality testing for the diagnosis of T-cell large granular lymphocytic leukemia: Are we identifying pathology or incidental clones?Int J Lab Hematol2022
35195689CAP-ACP Workload Model for Advanced Diagnostics in Precision Medicine.Am J Clin Pathol2022
32588428Clinical value of next-generation sequencing compared to cytogenetics in patients with suspected myelodysplastic syndrome.Br J Haematol2021
33824664Does HPV Subtype Predict Outcomes in Head and Neck Cancers?Int J Otolaryngol2021
33588906Low expression of NSD1, NSD2, and NSD3 define a subset of human papillomavirus-positive oral squamous carcinomas with unfavorable prognosis.Infect Agent Cancer2021
34475951Detection of Circulating Tumor DNA in Patients with Thyroid Nodules.Int J Endocrinol2021
32665881Multifocal CD4+ Primary Cutaneous Small/Medium Lymphoproliferative Disorder Successfully Treated With Low-Dose Oral Methotrexate: A Case Report.Cureus2020
31864959Spleen tyrosine kinase expression is correlated with human papillomavirus in head and neck cancer.Oral Oncol2020
31804024Erratum to: Disruption of the RICTOR/mTORC2 complex enhances the response of head and neck squamous cell carcinoma cells to PI3K inhibition.Mol Oncol2020
33059733TAM family receptors in conjunction with MAPK signalling are involved in acquired resistance to PI3Kα inhibition in head and neck squamous cell carcinoma.J Exp Clin Cancer Res2020
32654207Evaluating the impact of lymph node resampling on colorectal cancer nodal stage.Histopathology2020
30626742Mutational analysis of head and neck squamous cell carcinoma stratified by smoking status.JCI Insight2019
31844556Genomic and human papillomavirus profiling of an oral cancer cohort identifies TP53 as a predictor of overall survival.Cancers Head Neck2019
31177553Implementation of an NGS-based sequencing and gene fusion panel for clinical screening of patients with suspected hematologic malignancies.Eur J Haematol2019
31393061Disruption of the RICTOR/mTORC2 complex enhances the response of head and neck squamous cell carcinoma cells to PI3K inhibition.Mol Oncol2019
31138663<i>RB1</i> Deletion in Retinoblastoma Protein Pathway-Disrupted Cells Results in DNA Damage and Cancer Progression.Mol Cell Biol2019
29468544Immunohistochemical Detection of the Retinoblastoma Protein.Methods Mol Biol2018
30111332Comprehensive gene expression profiling identifies distinct and overlapping transcriptional profiles in non-specific interstitial pneumonia and idiopathic pulmonary fibrosis.Respir Res2018
30510993The Loss of ATRX Increases Susceptibility to Pancreatic Injury and Oncogenic KRAS in Female But Not Male Mice.Cell Mol Gastroenterol Hepatol2018
28403515An aggressive multifocal primary CNS histiocytosis with PTPN11 (Shp2) mutation.Neuropathol Appl Neurobiol2018
28067913Impaired H3K36 methylation defines a subset of head and neck squamous cell carcinomas.Nat Genet2017
29404507Sex-specific analysis post-liver transplantation in hemochromatosis with aplastic anemia and hepatocellular carcinoma.Hepatol Commun2017
28701342Activating transcription factor 3 promotes loss of the acinar cell phenotype in response to cerulein-induced pancreatitis in mice.Mol Biol Cell2017
26847730Amyloid deposition in extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue: A clinicopathologic study of 5 cases.Pathol Res Pract2016
26271341Feasibility of Targeting PIK3CA Mutations in Head and Neck Squamous Cell Carcinoma.Pathol Oncol Res2016
27676418Lack of matrix metalloproteinase 3 in mouse models of lung injury ameliorates the pulmonary inflammatory response in female but not in male mice.Exp Lung Res2016
27889452An RB-EZH2 Complex Mediates Silencing of Repetitive DNA Sequences.Mol Cell2016
27376475Clinical Next-Generation Sequencing Pipeline Outperforms a Combined Approach Using Sanger Sequencing and Multiplex Ligation-Dependent Probe Amplification in Targeted Gene Panel Analysis.J Mol Diagn2016
27275461In vitro three dimensional culture of hepatocellular carcinoma to measure prognosis and responsiveness to chemotherapeutic agents.Hepatobiliary Surg Nutr2016
26475095Loss of the retinoblastoma tumor suppressor correlates with improved outcome in patients with lung adenocarcinoma treated with surgery and chemotherapy.Hum Pathol2015
25240283Hotspot activating PRKD1 somatic mutations in polymorphous low-grade adenocarcinomas of the salivary glands.Nat Genet2014
23663293Does HPV type affect outcome in oropharyngeal cancer?J Otolaryngol Head Neck Surg2013
21358999Staged transcrusal and transsphenoidal endoscopic resection of an atypical clival melanoma: a case report and literature review.Skull Base2010
19861561Use of an elastic stain to show venous invasion in colorectal carcinoma: a simple technique for detection of an important prognostic factor.J Clin Pathol2009
15034035Monocyte surface-bound IL-15 can function as an activating receptor and participate in reverse signaling.J Immunol2004
11896602Membrane-anchored Cbl suppresses Hck protein-tyrosine kinase mediated cellular transformation.Oncogene2002
11971014Profound differences in leukocyte-endothelial cell responses to lipopolysaccharide versus lipoteichoic acid.J Immunol2002
10092522The proto-oncogene p120(Cbl) is a downstream substrate of the Hck protein-tyrosine kinase.Biochem Biophys Res Commun1999
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Collaborators

Anthony C Nichols
University of Western Ontario
Co-authored papers 14
John W Barrett
University of Western Ontario
Co-authored papers 13
Kevin Fung
Schulich School of Medicine & Dentistry, Western University, Victoria Hospital
Co-authored papers 11
Joe S Mymryk
University of Western Ontario
Co-authored papers 11
John Yoo
Schulich School of Medicine & Dentistry, Western University
Co-authored papers 11
William Stecho
University of Western Ontario
Co-authored papers 10
Stephanie Danielle MacNeil
Schulich School of Medicine and Dentistry, Western University
Co-authored papers 9
David A Palma
University of Western Ontario
Co-authored papers 8
Nicole Pinto
School of Public Policy at the University of Calgary
Co-authored papers 8
Paul Plantinga
University of Western Ontario
Co-authored papers 8
Kara M Ruicci
Schulich School of Medicine and Dentistry, Western University
Co-authored papers 6
Paul C Boutros
University of California los angeles
Co-authored papers 6
Eric Winquist
Schulich School of Medicine and Dentistry, University of Western Ontario
Co-authored papers 6
Matthew J Cecchini
Western University
Co-authored papers 6
Neil Mundi
Southern Illinois University School of Medicine
Co-authored papers 4
Frederick A Dick
Western University
Co-authored papers 4
Farhad Ghasemi
Western University
Co-authored papers 4
Sandeep Dhaliwal
University of California at Davis School of Medicine
Co-authored papers 4
Andrew Warner
Western University and London Regional Cancer Program
Co-authored papers 3
Mohammad Imran Khan
King Abdulaziz University (KAU), King Abdulaziz University
Co-authored papers 3
Laurie Ailles
University of Toronto
Co-authored papers 3
Krupal B Patel
Moffitt Cancer Center
Co-authored papers 3
Morgan Black
Schulich School of Medicine and Dentistry, Western University
Co-authored papers 3
Charles A Ishak
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 3
Bret Wehrli
Schulich School of Medicine & Dentistry, Western University
Co-authored papers 2
Keith Kwan
Western University
Co-authored papers 2
Steven F Gameiro
McMaster Immunology Research Centre, McMaster University
Co-authored papers 2
Axel Sahovaler
Schulich School of Medicine & Dentistry, Western University
Co-authored papers 2
Mushfiq H Shaikh
University of Western Ontario
Co-authored papers 2
Jalna Meens
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