Author details

Full Name

Safa Al-Sarraj

Affiliation

ORCID

Career Start Year

1994

Papers

212

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37163045	Creating the Pick's disease International Consortium: Association study of <i>MAPT</i> H2 haplotype with risk of Pick's disease.	medRxiv	2023
37373988	MGMT Promoter Methylation: Prognostication beyond Treatment Response.		2023
37362245	Case Report: Brainstem angiocentric glioma presenting in a toddler child-diagnostic and therapeutic challenges.		2023
36726473	Genome-wide characterization of mitochondrial DNA methylation in human brain.	Front Endocrinol (Lausanne)	2023
35107828	Multisystem screening reveals SARS-CoV-2 in neurons of the myenteric plexus and in megakaryocytes.	J Pathol	2022
35512359	Altered SOD1 maturation and post-translational modification in amyotrophic lateral sclerosis spinal cord.	Brain	2022
36008843	Co-deposition of SOD1, TDP-43 and p62 proteinopathies in ALS: evidence for multifaceted pathways underlying neurodegeneration.	Acta neuropathologica communications	2022
35488928	Axonal injury is detected by Î²APP immunohistochemistry in rapid death from head injury following road traffic collision.	International Journal of Legal Medicine	2022
35292638	Tau deposition patterns are associated with functional connectivity in primary tauopathies.	Nat Commun	2022
34551970	Repurposing Vandetanib plus Everolimus for the Treatment of <i>ACVR1</i>-Mutant Diffuse Intrinsic Pontine Glioma.	Cancer Discov	2022
32935873	Invited Review: The spectrum of neuropathology in COVID-19.	Neuropathology and Applied Neurobiology	2021
33589841	Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture.	Nat Genet	2021
33900873	High grade gliomas in young children: The South Thames Neuro-Oncology unit experience and recent advances in molecular biology and targeted therapies.	Pediatric Hematology and Oncology	2021
33619608	Spinal cord injury as an indicator of abuse in forensic assessment of abusive head trauma (AHT).	International Journal of Legal Medicine	2021
33663011	Concomitant neurodegenerative pathologies contribute to the transition from mild cognitive impairment to dementia.	Alzheimer's and Dementia	2021
33815817	The histone modification H3K4me3 is altered at the <i>ANK1</i> locus in Alzheimer's disease brain.	Future Sci OA	2021
30691312	Cranial vault unicameral bone cyst.	British Journal of Neurosurgery	2020
31786093	DNA methylation-based profiling for paediatric CNS tumour diagnosis and treatment: a population-based study.	Lancet Child Adolesc Health	2020
32238360	Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes.	Cancer Discov	2020
31996268	Analysis of neurodegenerative disease-causing genes in dementia with Lewy bodies.	Acta Neuropathol Commun	2020
31989247	5-ALA fluorescence in a WHO grade I papillary glioneuronal tumour: a case report.	Acta Neurochirurgica	2020
32454200	Primary Lumbar Paraganglioma: Clinical, Radiologic, Surgical, and Histopathologic Characteristics from a Case Series of 13 Patients.	World Neurosurgery	2020
32383020	Distribution patterns of tau pathology in progressive supranuclear palsy.	Acta Neuropathol	2020
32844161	Histopathological findings and viral tropism in UK patients with severe fatal COVID-19: a post-mortem study.	Lancet Microbe	2020
30660877	Adult Parasellar Capillary Hemangioma with Intrasellar Extension.	World Neurosurgery	2019
30448004	A comprehensive screening of copy number variability in dementia with Lewy bodies.	Neurobiol Aging	2019
30214067	Frequency and signature of somatic variants in 1461 human brain exomes.	Genet Med	2019
30439595	A cross-brain regions study of ANK1 DNA methylation in different neurodegenerative diseases.	Neurobiol Aging	2019
30348461	Striking phenotypic variation in a family with the P506S UBQLN2 mutation including amyotrophic lateral sclerosis, spastic paraplegia, and frontotemporal dementia.	Neurobiol Aging	2019
30739198	Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD.	Acta Neuropathol	2019
31018710	ATRX immunohistochemistry can help refine 'not elsewhere classified' categorisation for grade II/III gliomas.	British Journal of Neurosurgery	2019
30953760	Heritability and genetic variance of dementia with Lewy bodies.	Neurobiol Dis	2019
30898171	Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer's disease.	Clin Epigenetics	2019
30730007	Comparison of clinical and neuropathological diagnoses of neurodegenerative diseases in two centres from the Brains for Dementia Research (BDR) cohort.	Journal of Neural Transmission	2019
30784550	Primum non nocere: a call for balance when reporting on CTE.	Lancet Neurol	2019
29544907	Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3.	Neurobiol Aging	2018
30114415	Somatic variants in autosomal dominant genes are a rare cause of sporadic Alzheimer's disease.	Alzheimers Dement	2018
30066433	Variation at the TRIM11 locus modifies progressive supranuclear palsy phenotype.	Ann Neurol	2018
30349106	A histone acetylome-wide association study of Alzheimer's disease identifies disease-associated H3K27ac differences in the entorhinal cortex.	Nat Neurosci	2018
29967352	Functional diversity and cooperativity between subclonal populations of pediatric glioblastoma and diffuse intrinsic pontine glioma cells.	Nat Med	2018
29724592	Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study.	Lancet Neurol	2018
29533475	British Neuropathological Society and International Society of Forensic Radiology and Imaging expert consensus statement for post mortem neurological imaging.	Neuropathol Appl Neurobiol	2018
29566793	Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.	Neuron	2018
29263008	Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study.	Lancet Neurol	2018
29550519	Elevated DNA methylation across a 48-kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology.	Alzheimers Dement	2018
29332010	Oligogenic genetic variation of neurodegenerative disease genes in 980 postmortem human brains.	J Neurol Neurosurg Psychiatry	2018
28228164	Erratum to: Mitochondrial DNA point mutations and relative copy number in 1363 disease and control human brains.	Acta Neuropathol Commun	2017
28469040	Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis.	Sci Transl Med	2017
28603852	Unusual neuropathological features and increased brain aluminium in a resident of Camelford, UK.	Neuropathology and Applied Neurobiology	2017
28377258	Cavernoma: New Insights From an Unusual Case.	World Neurosurgery	2017