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Author Details

Brenda D Moore
College of Medicine, University of Florida
2006
24
18
PMIDPaper TitleJournal TitlePublished Year
35494163Soluble brain homogenates from diverse human and mouse sources preferentially seed diffuse Aβ plaque pathology when injected into newborn mouse hosts.Free Neuropathol2022
34127518Microglia show differential transcriptomic response to Aβ peptide aggregates ex vivo and in vivo.Life Sci Alliance2021
33588898Remodeling Alzheimer-amyloidosis models by seeding.Mol Neurodegener2021
33069251Aÿ40 displays amyloidogenic properties in the non-transgenic mouse brain but does not exacerbate Aÿ42 toxicity in Drosophila.Alzheimers Res Ther2020
31791377Organotypic brain slice cultures to model neurodegenerative proteinopathies.Mol Neurodegener2019
29208777Short Aβ peptides attenuate Aβ42 toxicity in vivo.J Exp Med2018
30158114TLR5 decoy receptor as a novel anti-amyloid therapeutic for Alzheimer's disease.J Exp Med2018
29608591Novel monoclonal antibodies targeting the microtubule-binding domain of human tau.PLoS One2018
28760159Generation and characterization of new monoclonal antibodies targeting the PHF1 and AT8 epitopes on human tau.Acta Neuropathol Commun2017
28910367A novel panel of α-synuclein antibodies reveal distinctive staining profiles in synucleinopathies.PLoS One2017
25619653IL-10 alters immunoproteostasis in APP mice, increasing plaque burden and worsening cognitive behavior.Neuron2015
24984882Divergent effects of the H50Q and G51D SNCA mutations on the aggregation of α-synuclein.J Neurochem2014
23512986Cytosolic proteins lose solubility as amyloid deposits in a transgenic mouse model of Alzheimer-type amyloidosis.Hum Mol Genet2013
23716494Steroids as γ-secretase modulators.FASEB J2013
23447589Reversible pathologic and cognitive phenotypes in an inducible model of Alzheimer-amyloidosis.J Neurosci2013
22621179Overlapping profiles of Aβ peptides in the Alzheimer's disease and pathological aging brains.Alzheimers Res Ther2012
23043097Retention in endoplasmic reticulum 1 (RER1) modulates amyloid-β (Aβ) production by altering trafficking of γ-secretase and amyloid precursor protein (APP).J Biol Chem2012
21868378Lysine 624 of the amyloid precursor protein (APP) is a critical determinant of amyloid β peptide length: support for a sequential model of γ-secretase intramembrane proteolysis and regulation by the amyloid β precursor protein (APP) juxtamembrane region.J Biol Chem2011
19189374Rationally designed dehydroalanine (DeltaAla)-containing peptides inhibit amyloid-beta (Abeta) peptide aggregation.Biopolymers2009
19916493Biophysical analyses of synthetic amyloid-beta(1-42) aggregates before and after covalent cross-linking. Implications for deducing the structure of endogenous amyloid-beta oligomers.Biochemistry2009
18548070Substrate-targeting gamma-secretase modulators.Nature2008
18524908BRI2 (ITM2b) inhibits Abeta deposition in vivo.J Neurosci2008
17910477Amyloid-beta(1-42) rapidly forms protofibrils and oligomers by distinct pathways in low concentrations of sodium dodecylsulfate.Biochemistry2007
16834338Secondary structure and interfacial aggregation of amyloid-beta(1-40) on sodium dodecyl sulfate micelles.Biochemistry2006
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Collaborators

Todd E Golde
Emory Center for Neurodegenerative Disease
Co-authored papers 18
Paramita Chakrabarty
Center for Translational Research in Neurodegenerative Disease, University of Florida
Co-authored papers 7
Yona Levites
Emory University School of Medicine
Co-authored papers 7
Carolina Ceballos-Diaz
Center for Translational Research in Neurodegenerative Disease, University of Florida
Co-authored papers 5
Pedro E Cruz
College of Medicine, University of Florida
Co-authored papers 4
Dennis W Dickson
Mayo Clinic Jacksonville
Co-authored papers 4
Christopher Janus
College of Medicine, University of Florida
Co-authored papers 4
Awilda M Rosario
Center for Translational Research in Neurodegenerative Disease, University of Florida
Co-authored papers 3
Christophe Verbeeck
Mayo Clinic College of Medicine
Co-authored papers 3
Pritam Das
Institute of Medical Sciences, Banaras Hindu University
Co-authored papers 3
Cory C Funk
Institute for Systems Biology
Co-authored papers 3
Nil??fer Ertekin-Taner
Mayo Clinic
Co-authored papers 2
Steven G Younkin
Mayo Clinic
Co-authored papers 2
Diego E Rincon-Limas
University of Florida
Co-authored papers 2
Andrew Li
Center for Translational Research in Neurodegenerative Disease, University of Florida
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Xue Wang
Mayo Clinic
Co-authored papers 2
Mariet Allen
Mayo Clinic
Co-authored papers 2
Nathan D Price
Institute for Systems Biology
Co-authored papers 2
Jeremy D Burgess
Mayo Clinic
Co-authored papers 1
James A Eddy
Benaroya Research Institute at Virginia Mason, Institute for Systems Biology, Sage Bionetworks, University of Illinois at Urbana-Champaign
Co-authored papers 1
Fanggeng Zou
Cincinnati Children's Hospital Medical Center
Co-authored papers 1
Neill R Graff-Radford
Mayo Clinic Florida
Co-authored papers 1
Curtis S Younkin
Mayo Clinic
Co-authored papers 1
Karen N McFarland
Center for Translational Research in Neurodegenerative Disease, University of Florida
Co-authored papers 1
Amanda N Sacino
Johns Hopkins University School of Medicine
Co-authored papers 1
Hongdong Li
Gannan Medical University
Co-authored papers 1
Joseph S Reddy
Mayo Clinic
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Kevin H Strang
College of Medicine, University of Florida
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Release 1.2