Author details

Full Name

Roger E McLendon

Affiliation

ORCID

Career Start Year

1968

Papers

395

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36534983	Corrigendum to: Molecular biomarker-defined brain tumors: Epidemiology, validity, and completeness in the United States.	Neuro Oncol	2023
36301489	CD155 is a putative therapeutic target in medulloblastoma.	Clin Transl Oncol	2023
37760589	Repurposing Clemastine to Target Glioblastoma Cell Stemness.	Cancers (Basel)	2023
36753564	Immunotoxin-Î±CD40 therapy activates innate and adaptive immunity and generates a durable antitumor response in glioblastoma models.		2023
37004712	Recombinant polio-rhinovirus immunotherapy for recurrent paediatric high-grade glioma: a phase 1b trial.		2023
34763992	Central Nervous System Tumor Classification: An Update on the Integration of Tumor Genetics.	Hematology/Oncology Clinics of North America	2022
35460555	Molecular biomarker-defined brain tumors: Epidemiology, validity, and completeness in the United States.	Neuro Oncol	2022
36131014	Failure of human rhombic lip differentiation underlies medulloblastoma formation.	Nature	2022
35859542	Aligning the Central Brain Tumor Registry of the United States (CBTRUS) histology groupings with current definitions.	Neurooncol Pract	2022
36446943	Author Correction: Failure of human rhombic lip differentiation underlies medulloblastoma formation.	Nature	2022
34593527	A Modified Nucleoside 6-Thio-2'-Deoxyguanosine Exhibits Antitumor Activity in Gliomas.	Clin Cancer Res	2021
33741928	The transcriptional landscape of Shh medulloblastoma.	Nat Commun	2021
33580238	Ultra high-risk PFA ependymoma is characterized by loss of chromosome 6q.	Neuro Oncol	2021
33783952	Histologic maturation of cerebral neuroblastoma following conventional chemotherapy.	Pediatric Blood and Cancer	2021
33502920	Clinical Outcomes and Patient-Matched Molecular Composition of Relapsed Medulloblastoma.	J Clin Oncol	2021
33441554	Very low mutation burden is a feature of inflamed recurrent glioblastomas responsive to cancer immunotherapy.	Nat Commun	2021
34409497	Subgroup and subtype-specific outcomes in adult medulloblastoma.	Acta Neuropathol	2021
34599823	An Unusual Ganglioglioma with Pseudopapillary Features and PRKAR2B-BRAF Fusion.	Journal of Neuropathology and Experimental Neurology	2021
32555164	The integrated genomic and epigenomic landscape of brainstem glioma.	Nature Communications	2020
31744830	Targeting PD-L1 Initiates Effective Antitumor Immunity in a Murine Model of Cushing Disease.	Clinical Cancer Research	2020
31732806	Desmoplastic myxoid tumor, SMARCB1-mutant: clinical, histopathological and molecular characterization of a pineal region tumor encountered in adolescents and adults.	Acta Neuropathol	2020
32743560	Pattern of Relapse and Treatment Response in WNT-Activated Medulloblastoma.	Cell Rep Med	2020
30833574	ACVR1 R206H cooperates with H3.1K27M in promoting diffuse intrinsic pontine glioma pathogenesis.	Nat Commun	2019
31850213	Recurrent Extradural Myxopapillary Ependymoma With Oligometastatic Spread.	Front Oncol	2019
31807694	Massive clonal expansion of medulloblastoma-specific T cells during adoptive cellular therapy.	Sci Adv	2019
32642665	Performance of a nomogram for IDH-wild-type glioblastoma patient survival in an elderly cohort.	Neurooncol Adv	2019
30551183	Two Extraordinary Sellar Neuronal Tumors: Literature Review and Comparison of Clinicopathologic Features.	American Journal of Clinical Pathology	2019
30500933	MGMT: Immunohistochemical Detection in High-Grade Astrocytomas.	Journal of Neuropathology and Experimental Neurology	2019
30346624	Sensitive and rapid detection of TERT promoter and IDH mutations in diffuse gliomas.	Neuro-Oncology	2019
30561708	Intraventricular Pilocytic Astrocytoma With KIAA1549/BRAF Fusion Arising in a 44-Year Old.	Journal of Neuropathology and Experimental Neurology	2019
31040154	MTAP Loss Promotes Stemness in Glioblastoma and Confers Unique Susceptibility to Purine Starvation.	Cancer Research	2019
30876455	Genomic analysis demonstrates that histologically-defined astroblastomas are molecularly heterogeneous and that tumors with MN1 rearrangement exhibit the most favorable prognosis.	Acta Neuropathol Commun	2019
30958386	Sudden Unexpected Death in a Child From an Anaplastic Ependymoma.	American Journal of Forensic Medicine and Pathology	2019
31361005	Glioneuronal Tumor With Features of Ganglioglioma and Neurocytoma Arising in the Fourth Ventricle: A Report of 2 Unusual Cases and a Review of Infratentorial Gangliogliomas.	Journal of Neuropathology and Experimental Neurology	2019
29802247	The genomic landscape of TERT promoter wildtype-IDH wildtype glioblastoma.	Nat Commun	2018
30159860	Molecular profiling of different glioma specimens from an Ollier disease patient suggests a multifocal disease process in the setting of IDH mosaicism.	Brain Tumor Pathology	2018
30019219	Heterogeneity within the PF-EPN-B ependymoma subgroup.	Acta Neuropathol	2018
29878245	Poliovirus Receptor (CD155) Expression in Pediatric Brain Tumors Mediates Oncolysis of Medulloblastoma and Pleomorphic Xanthoastrocytoma.	J Neuropathol Exp Neurol	2018
30053065	Intracerebral Flexner-Wintersteiner Rosette-Rich Tumor With Somatic RB1 Mutation: A CNS Embryonal Tumor With Retinoblastic Differentiation.	Journal of Neuropathology and Experimental Neurology	2018
30041899	Hyaluronic acid based low viscosity hydrogel as a novel carrier for Convection Enhanced Delivery of CAR T cells.	J Clin Neurosci	2018
30039530	Novel case of recurrent intraventricular atypical central neurocytoma with prominent gangliogliomatous differentiation in a 10-year-old boy with 10 years of follow up.	Neuropathology	2018
29943666	Recurrent Glioblastoma Treated with Recombinant Poliovirus.	New England Journal of Medicine	2018
30409555	Tissue is the Issue: Biomarkers of Prognosis and Classification in Adult Gliomas.	Seminars in Oncology Nursing	2018
30079884	Sulfonylurea receptor 1 expression is variable in adult and pediatric brain tumors.	Clinical Neuropathology	2018
29097607	Adaptive Evolution of the GDH2 Allosteric Domain Promotes Gliomagenesis by Resolving IDH1-Induced Metabolic Liabilities.	Cancer Research	2018
29093005	Dendritic Cells Enhance Polyfunctionality of Adoptively Transferred T Cells That Target Cytomegalovirus in Glioblastoma.	Cancer Research	2018
29703821	A Rationally Designed Fully Human EGFRvIII:CD3-Targeted Bispecific Antibody Redirects Human T Cells to Treat Patient-derived Intracerebral Malignant Glioma.	Clinical Cancer Research	2018
28148827	Mutant IDH1 Disrupts the Mouse Subventricular Zone and Alters Brain Tumor Progression.	Molecular Cancer Research	2017
28726821	The whole-genome landscape of medulloblastoma subtypes.	Nature	2017
28725786	Structured Annual Faculty Review Program Accelerates Professional Development and Promotion: Long-Term Experience of the Duke University Medical Center's Pathology Department.	Academic Pathology	2017