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Author Details

Wolfgang Sad??e
College of Medicine, The Ohio State University
1967
363
72
PMIDPaper TitleJournal TitlePublished Year
36927888Pharmacogenomics: Driving Personalized Medicine.Pharmacol Rev2023
37687205Ligand-Free Signaling of G-Protein-Coupled Receptors: Physiology, Pharmacology, and Genetics.Molecules2023
35192625Interpreting coronary artery disease GWAS results: A functional genomics approach assessing biological significance.PLoS One2022
36551817Transcription Factors and ncRNAs Associated with <i>CYP3A</i> Expression in Human Liver and Small Intestine Assessed with Weighted Gene Co-Expression Network Analysis.Biomedicines2022
36144565Ligand-Free Signaling of G-Protein-Coupled Receptors: Relevance to μ Opioid Receptors in Analgesia and Addiction.Molecules2022
32943400Phagosome-regulated mTOR signalling during sarcoidosis granuloma biogenesis.Eur Respir J2021
33716726Pharmacological Prevention of Neonatal Opioid Withdrawal in a Pregnant Guinea Pig Model.Front Pharmacol2021
33649515Functional CYP3A variants affecting tacrolimus trough blood concentrations in Chinese renal transplant recipients.Pharmacogenomics J2021
33540508Sulfatase 2 Is Associated with Steroid Resistance in Childhood Nephrotic Syndrome.J Clin Med2021
32322562Challenges of Immune Response Diversity in the Human Population Concerning New Tuberculosis Diagnostics, Therapies, and Vaccines.Front Cell Infect Microbiol2020
32932935Biased Opioid Antagonists as Modulators of Opioid Dependence: Opportunities to Improve Pain Therapy and Opioid Use Management.Molecules2020
32988896Association of <i>ANRIL</i> Polymorphism With Overall Survival in Adult Patients With Hematologic Malignancies After Allogeneic Hematopoietic Stem Cell Transplantation.Anticancer Res2020
30520769CYP2D6 haplotypes with enhancer single-nucleotide polymorphism rs5758550 and rs16947 (*2 allele): implications for CYP2D6 genotyping panels.Pharmacogenet Genomics2019
31728800Association of Regulatory Genetic Variants for Protein Kinase Cα with Mortality and Drug Efficacy in Patients with Heart Failure.Cardiovasc Drugs Ther2019
30134122IL-13-regulated Macrophage Polarization during Granuloma Formation in an In Vitro Human Sarcoidosis Model.Am J Respir Cell Mol Biol2019
31399483Ligand-Free Estrogen Receptor α (ESR1) as Master Regulator for the Expression of CYP3A4 and Other Cytochrome P450 Enzymes in the Human Liver.Mol Pharmacol2019
31025317Significant association of DRD2 enhancer variant rs12364283 with heroin addiction in a Pakistani population.Ann Hum Genet2019
30756358Association of Genetic Polymorphisms in the Beta-1 Adrenergic Receptor with Recovery of Left Ventricular Ejection Fraction in Patients with Heart Failure.J Cardiovasc Transl Res2019
28945944Whole Transcriptome Profiling: An RNA-Seq Primer and Implications for Pharmacogenomics Research.Clin Transl Sci2018
29925376Blood pressure signature genes and blood pressure response to thiazide diuretics: results from the PEAR and PEAR-2 studies.BMC Med Genomics2018
30197492Testing genetic modifiers of behavior and response to atomoxetine in autism spectrum disorder with ADHD.J Dev Phys Disabil2018
29847580AmpliSeq transcriptome analysis of human alveolar and monocyte-derived macrophages over time in response to Mycobacterium tuberculosis infection.PLoS One2018
30453884Combined genetic influence of the nicotinic receptor gene cluster CHRNA5/A3/B4 on nicotine dependence.BMC Genomics2018
30354296Interactions Between Regulatory Variants in CYP7A1 (Cholesterol 7α-Hydroxylase) Promoter and Enhancer Regions Regulate CYP7A1 Expression.Circ Genom Precis Med2018
29730891Alpha-synuclein mRNA isoform formation and translation affected by polymorphism in the human SNCA 3'UTR.Mol Genet Genomic Med2018
29650764Genetic Variants Influencing Plasma Renin Activity in Hypertensive Patients From the PEAR Study (Pharmacogenomic Evaluation of Antihypertensive Responses).Circ Genom Precis Med2018
26856248Transcriptomic variation of pharmacogenes in multiple human tissues and lymphoblastoid cell lines.Pharmacogenomics J2017
28188910Expression and splicing of ABC and SLC transporters in the human blood-brain barrier measured with RNAseq.Eur J Pharm Sci2017
28493098Personalized Therapeutics and Pharmacogenomics: Integral to Personalized Health Care.Pharm Res2017
28181117CYP2D6 Genetic Variation and Beta-Blocker Maintenance Dose in Patients with Heart Failure.Pharm Res2017
28120175Regulatory Variants Modulate Protein Kinase C α (PRKCA) Gene Expression in Human Heart.Pharm Res2017
28115488Genome-Wide Prioritization and Transcriptomics Reveal Novel Signatures Associated With Thiazide Diuretics Blood Pressure Response.Circ Cardiovasc Genet2017
28090649The Pharmacogenomics Research Network Translational Pharmacogenetics Program: Outcomes and Metrics of Pharmacogenetic Implementations Across Diverse Healthcare Systems.Clin Pharmacol Ther2017
29050765Alveolar macrophages from tuberculosis patients display an altered inflammatory gene expression profile.Tuberculosis (Edinb)2017
29120360Elemental Ingredients in the Macrophage Cocktail: Role of ZIP8 in Host Response to Mycobacterium tuberculosis.Int J Mol Sci2017
29167564Whole Transcriptome Sequencing Analyses Reveal Molecular Markers of Blood Pressure Response to Thiazide Diuretics.Sci Rep2017
28598206A Novel In Vitro Human Granuloma Model of Sarcoidosis and Latent Tuberculosis Infection.Am J Respir Cell Mol Biol2017
28617822Intronic SNP in ESR1 encoding human estrogen receptor alpha is associated with brain ESR1 mRNA isoform expression and behavioral traits.PLoS One2017
27758088The CHRNA5/CHRNA3/CHRNB4 Nicotinic Receptor Regulome: Genomic Architecture, Regulatory Variants, and Clinical Associations.Hum Mutat2017
26871237Regulatory effects of genomic translocations at the human carboxylesterase-1 (CES1) gene locus.Pharmacogenet Genomics2016
26488616CYP3A4 intronic SNP rs35599367 (CYP3A4*22) alters RNA splicing.Pharmacogenet Genomics2016
27640124Non-linear interactions between candidate genes of myocardial infarction revealed in mRNA expression profiles.BMC Genomics2016
27666482Gene expression profiling of brain samples from patients with Lewy body dementia.Biochem Biophys Res Commun2016
27912746Erratum to: Non-linear interactions between candidate genes of myocardial infarction revealed in mRNA expression profiles.BMC Genomics2016
27148966Human Bacterial Artificial Chromosome (BAC) Transgenesis Fully Rescues Noradrenergic Function in Dopamine β-Hydroxylase Knockout Mice.PLoS One2016
27189967Preferential Delivery of an Opioid Antagonist to the Fetal Brain in Pregnant Mice.J Pharmacol Exp Ther2016
25577610Cladograms with Path to Event (ClaPTE): a novel algorithm to detect associations between genotypes or phenotypes using phylogenies.Comput Biol Med2015
26331722Allele-Selective Transcriptome Recruitment to Polysomes Primed for Translation: Protein-Coding and Noncoding RNAs, and RNA Isoforms.PLoS One2015
26597164RNA sequencing of transcriptomes in human brain regions: protein-coding and non-coding RNAs, isoforms and alleles.BMC Genomics2015
26338265The epigenome, 4D nucleome and next-generation neuropsychiatric pharmacogenomics.Pharmacogenomics2015
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Collaborators

Julie A Johnson
Department of Pharmacotherapy and Translational Research, University of Florida
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Larry S Schlesinger
Texas Biomedical Research Institute
Co-authored papers 9
Rhonda M Cooper-DeHoff
College of Medicine, University of Florida
Co-authored papers 8
Andrew D Johnson
and Blood Institute
Co-authored papers 7
Taimour Y Langaee
Center for Pharmacogenomics and Precision Medicine, University of Florida
Co-authored papers 7
Amber L Beitelshees
University of Maryland School of Medicine
Co-authored papers 6
Steven E Scherer
Baylor College of Medicine
Co-authored papers 5
Peter J Embi
Vanderbilt University Medical Center
Co-authored papers 4
Kevin Sweet
College of Medicine, The Ohio State University
Co-authored papers 4
Stephen T Turner
Mayo Clinic
Co-authored papers 4
Eric Boerwinkle
Baylor College of Medicine
Co-authored papers 4
Caitrin W McDonough
Department of Pharmacotherapy and Translational Research, University of Florida
Co-authored papers 4
Maria Kataki
Gauhati Medical College & Hospital
Co-authored papers 4
Josh F Peterson
Vanderbilt University Medical Center
Co-authored papers 3
John N Weinstein
The University of Texas MD Anderson Cancer Center
Co-authored papers 3
Kandamurugu Manickam
Nationwide Children's Hospital, The Ohio State University College of Medicine
Co-authored papers 3
Deanna L Kroetz
University of California San Francisco
Co-authored papers 3
Bradford W Gibson
The Buck Institute for Research on Aging
Co-authored papers 3
William C Reinhold
Center for Cancer Research, National Cancer Institute
Co-authored papers 3
Peter White
The Ohio State University
Co-authored papers 3
Nicholas J Schork
University of California San Diego
Co-authored papers 3
Douglas W Scharre
Ohio State University
Co-authored papers 3
Teri E Klein
Stanford University
Co-authored papers 3
Cyrine E Haidar
St. Jude Children's Research Hospital
Co-authored papers 2
Jonathan S Schildcrout
Vanderbilt University Medical Center.
Co-authored papers 2
Ruth E Pakyz
University of Maryland
Co-authored papers 2
Amanda R Elsey
Department of Pharmacotherapy and Translational Research, University of Florida
Co-authored papers 2
Kathleen Palmer
University of Maryland School of Medicine
Co-authored papers 2
Jill M Pulley
Vanderbilt University School of Medicine
Co-authored papers 2
Kathleen M Giacomini
University of California San Francisco
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Release 1.2