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Author Details

Vivian H Gersuk
Center for Systems Immunology, Benaroya Research Institute
1993
46
23
PMIDPaper TitleJournal TitlePublished Year
37432736Responders to low-dose ATG induce CD4+ T cell exhaustion in type 1 diabetes.JCI Insight2023
37751304Islet-autoreactive CD4+ T cells are linked with response to alefacept in type 1 diabetes.JCI Insight2023
37978185The transcriptional and phenotypic characteristics that define alveolar macrophage subsets in acute hypoxemic respiratory failure.Nat Commun2023
34816633Pcsk9 Deletion Promotes Murine Nonalcoholic Steatohepatitis and Hepatic Carcinogenesis: Role of Cholesterol.Hepatol Commun2022
35831640Presymptomatic diagnosis of postoperative infection and sepsis using gene expression signatures.Intensive Care Med2022
36418348Inflammatory bone marrow signaling in pediatric acute myeloid leukemia distinguishes patients with poor outcomes.Nat Commun2022
35266148Oral desensitization therapy for peanut allergy induces dynamic changes in peanut-specific immune responses.Allergy2022
35020411Deep immune phenotyping reveals similarities between aging, Down syndrome, and autoimmunity.Sci Transl Med2022
34124936The Cyclin-Dependent Kinase 8 (CDK8) Inhibitor DCA Promotes a Tolerogenic Chemical Immunophenotype in CD4<sup>+</sup> T Cells via a Novel CDK8-GATA3-FOXP3 Pathway.Mol Cell Biol2021
34806648Autoreactive T cell receptors with shared germline-like α chains in type 1 diabetes.JCI Insight2021
29377961Shared and organism-specific host responses to childhood diarrheal diseases revealed by whole blood transcript profiling.PLoS One2018
28031441Modular transcriptional repertoire analyses identify a blood neutrophil signature as a candidate biomarker for lupus nephritis.Rheumatology (Oxford)2017
28566371Single-Cell RNA Sequencing Reveals Expanded Clones of Islet Antigen-Reactive CD4<sup>+</sup> T Cells in Peripheral Blood of Subjects with Type 1 Diabetes.J Immunol2017
28768806A phenotypically and functionally distinct human T<sub>H</sub>2 cell subpopulation is associated with allergic disorders.Sci Transl Med2017
28009047Longitudinal monitoring of gene expression in ultra-low-volume blood samples self-collected at home.Clin Exp Immunol2017
27002799Vitamin D Deficiency Is Associated With Increased Risk of Non-alcoholic Steatohepatitis in Adults With Non-alcoholic Fatty Liver Disease: Possible Role for MAPK and NF-κB?Am J Gastroenterol2016
28664195Partial exhaustion of CD8 T cells and clinical response to teplizumab in new-onset type 1 diabetes.Sci Immunol2016
27534558Blood-Borne RNA Correlates with Disease Activity and IFN-Stimulated Gene Expression in Systemic Lupus Erythematosus.J Immunol2016
27042306Acute hyperglycemia impairs IL-6 expression in humans.Immun Inflamm Dis2016
26795118Neuroinvasive West Nile Infection Elicits Elevated and Atypically Polarized T Cell Responses That Promote a Pathogenic Outcome.PLoS Pathog2016
26267155Comparison of biomarkers for systemic juvenile idiopathic arthritis.Pediatr Res2015
26653891MAST: a flexible statistical framework for assessing transcriptional changes and characterizing heterogeneity in single-cell RNA sequencing data.Genome Biol2015
24430436Low HERV-K(C4) copy number is associated with type 1 diabetes.Diabetes2014
24844227Avidity-dependent programming of autoreactive T cells in T1D.PLoS One2014
24612859A transcriptomic reporter assay employing neutrophils to measure immunogenic activity of septic patients' plasma.J Transl Med2014
24644022Modular transcriptional repertoire analyses of adults with systemic lupus erythematosus reveal distinct type I and type II interferon signatures.Arthritis Rheumatol2014
23380815Allelic exclusion and peripheral reconstitution by TCR transgenic T cells arising from transduced human hematopoietic stem/progenitor cells.Mol Ther2013
20054344Insulin gene VNTR genotype associates with frequency and phenotype of the autoimmune response to proinsulin.Genes Immun2010
20533289A functional RANKL polymorphism associated with younger age at onset of rheumatoid arthritis.Arthritis Rheum2010
20120618Does narcolepsy symptom severity vary according to HLA-DQB1*0602 allele status?Sleep2010
19013100Prevalence of narcolepsy in King County, Washington, USA.Sleep Med2009
19950324A prospective approach to investigating the natural history of preclinical rheumatoid arthritis (RA) using first-degree relatives of probands with RA.Arthritis Rheum2009
19357791The toll-like receptor signaling molecule Myd88 contributes to pancreatic beta-cell homeostasis in response to injury.PLoS One2009
19482555Changes in autoreactive T cell avidity during type 1 diabetes development.Clin Immunol2009
19317743A real-time polymerase chain reaction assay for the rapid identification of the autoimmune disease-associated allele HLA-DQB1*0602.Tissue Antigens2009
16572445Association of tumor necrosis factor alpha polymorphism, but not the shared epitope, with increased radiographic progression in a seropositive rheumatoid arthritis inception cohort.Arthritis Rheum2006
17055527A real-time PCR approach for rapid high resolution subtyping of HLA-DRB1*04.J Immunol Methods2006
15047612Differential recognition and activation thresholds in human autoreactive GAD-specific T-cells.Diabetes2004
15476205Interaction between RANKL and HLA-DRB1 genotypes may contribute to younger age at onset of seropositive rheumatoid arthritis in an inception cohort.Arthritis Rheum2004
14597769Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25- T cells.J Clin Invest2003
11905849Complexity of human immune response profiles for CD4+ T cell epitopes from the diabetes autoantigen GAD65.Autoimmunity2001
11290812Intermolecular antigen spreading occurs during the preclinical period of human type 1 diabetes.J Immunol2001
9709176HLA-DRB1 typing in rheumatoid arthritis: predicting response to specific treatments.Ann Rheum Dis1998
8833044Prognostic implications of HLA genotyping in the early assessment of patients with rheumatoid arthritis.J Rheumatol Suppl1996
7789980Molecular cloning and chromosomal localization of a pseudogene related to the human acyl-CoA binding protein/diazepam binding inhibitor.Genomics1995
8480168Database contamination.Science1993
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Collaborators

Gerald T Nepom
Wash Benaroya Research Institute at Virginia Mason
Co-authored papers 18
Peter S Linsley
8Benaroya Research Institute
Co-authored papers 11
Carla J Greenbaum
Center for Interventional Immunology, Benaroya Research Institute at Virginia Mason
Co-authored papers 10
Damien Chaussabel
Co-authored papers 9
Cate Speake
Center for Interventional Immunology, Benaroya Research Institute at Virginia Mason
Co-authored papers 8
Hannah A DeBerg
Benaroya Research Institute at Virginia Mason
Co-authored papers 6
William W Kwok
Center for Translational Immunology, Benaroya Research Institute at Virginia Mason
Co-authored papers 5
Jane H Buckner
Center for Translational Immunology, Benaroya Research Institute at Virginia Mason
Co-authored papers 4
Erik Wambre
Precision Immunology Institute, Icahn School of Medicine at Mount Sinai
Co-authored papers 3
Karen Cerosaletti
Center for Translational Immunology
Co-authored papers 3
Sarah Alice Long
Center for Translational Immunology, Benaroya Research Institute at Virginia Mason
Co-authored papers 3
Kaitlin J Flynn
Center for Systems Immunology, Benaroya Research Institute at Virginia Mason
Co-authored papers 3
Scott Presnell
Benaroya Research Institute
Co-authored papers 2
Alice E Wiedeman
Center for Translational Immunology, Benaroya Research Institute at Virginia Mason
Co-authored papers 2
Todd M Brusko
College of Medicine, Diabetes Institute, University of Florida
Co-authored papers 2
Jerill Thorpe
Benaroya Research Institute at Virginia Mason
Co-authored papers 2
Matthew C Altman
University of Washington School of Medicine, Seattle Benaroya Research Institute
Co-authored papers 2
Martin Prlic
Fred Hutchinson Cancer Research Center
Co-authored papers 2
Helena Reijonen
City of Hope Medical Center, Beckman Research Institute
Co-authored papers 2
Elisa Balmas
Center for Translational Immunology
Co-authored papers 2
Raphael Gottardo
Fred Hutchinson Cancer Center
Co-authored papers 2
James A Eddy
Benaroya Research Institute at Virginia Mason, Institute for Systems Biology, Sage Bionetworks, University of Illinois at Urbana-Champaign
Co-authored papers 2
Mario G Rosasco
Center for Systems Immunology, Benaroya Research Institute
Co-authored papers 2
Elisavet Serti
The Henry Jackson Foundation.
Co-authored papers 2
Colin O'Rourke
Center for Interventional Immunology, Benaroya Research Institute at Virginia Mason
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Fariba Barahmand-Pour
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Bernard Khor
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Alex Hu
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Philip J Norris
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Release 1.2