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Author Details
Full Name
Loren Miraglia
Affiliation
Genomics Institute of the Novartis Research Foundation
ORCID
Career Start Year
1991
Papers
45
H Index
29
Expertise
CM4AI Collaborator
Trey Ideker (CM4AI)
PMID
Paper Title
Journal Title
Published Year
33443164
A genome-wide microRNA screen identifies the microRNA-183/96/182 cluster as a modulator of circadian rhythms.
Proc Natl Acad Sci U S A
2021
34526658
EndoBind detects endogenous protein-protein interactions in real time.
Commun Biol
2021
29671265
Making It All Work: Functional Genomics and Reporter Gene Assays.
Methods Mol Biol
2018
30297964
Guide Swap enables genome-scale pooled CRISPR-Cas9 screening in human primary cells.
Nat Methods
2018
29671267
Reporter Gene Assays Using Viral Functional Genomics Libraries.
Methods Mol Biol
2018
29671266
Reporter Gene Assays Using Transfectable Functional Genomics Libraries.
Methods Mol Biol
2018
28068668
The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERα.
Nature
2017
28569745
The microprotein Minion controls cell fusion and muscle formation.
Nat Commun
2017
27649498
High Throughput Random Mutagenesis and Single Molecule Real Time Sequencing of the Muscle Nicotinic Acetylcholine Receptor.
PLoS One
2016
27610566
Domestication and Divergence of Saccharomyces cerevisiae Beer Yeasts.
Cell
2016
25616511
Genome-Engineering Tools to Establish Accurate Reporter Cell Lines That Enable Identification of Therapeutic Strategies to Treat Friedreich's Ataxia.
J Biomol Screen
2015
24725410
SWELL1, a plasma membrane protein, is an essential component of volume-regulated anion channel.
Cell
2014
24886841
High throughput mutagenesis for identification of residues regulating human prostacyclin (hIP) receptor expression and function.
PLoS One
2014
23603119
Akt-mediated phosphorylation of argonaute 2 downregulates cleavage and upregulates translational repression of MicroRNA targets.
Mol Cell
2013
22423970
Cofactors required for TLR7- and TLR9-dependent innate immune responses.
Cell Host Microbe
2012
21564017
Seeing the light: luminescent reporter gene assays.
Comb Chem High Throughput Screen
2011
21949408
Tumor suppressor protein (p)53, is a regulator of NF-kappaB repression by the glucocorticoid receptor.
Proc Natl Acad Sci U S A
2011
20027183
Human host factors required for influenza virus replication.
Nature
2010
20696907
Identification of RING finger protein 4 (RNF4) as a modulator of DNA demethylation through a functional genomics screen.
Proc Natl Acad Sci U S A
2010
20085741
An RNAi screen identifies TRRAP as a regulator of brain tumor-initiating cell differentiation.
Cell Stem Cell
2010
19340300
A functional screen for regulators of CKDN2A reveals MEOX2 as a transcriptional activator of INK4a.
PLoS One
2009
19765810
A genome-wide RNAi screen for modifiers of the circadian clock in human cells.
Cell
2009
19805117
A genomic screen identifies TYRO3 as a MITF regulator in melanoma.
Proc Natl Acad Sci U S A
2009
18854154
Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication.
Cell
2008
18077367
A coactivator trap identifies NONO (p54nrb) as a component of the cAMP-signaling pathway.
Proc Natl Acad Sci U S A
2007
17939994
A role for IkappaB kinase 2 in bipolar spindle assembly.
Proc Natl Acad Sci U S A
2007
16474406
Feedback repression is required for mammalian circadian clock function.
Nat Genet
2006
17001007
Genome-wide functional analysis of human cell-cycle regulators.
Proc Natl Acad Sci U S A
2006
17110210
High-content screening of functional genomic libraries.
Methods Enzymol
2006
15312651
A functional genomics strategy reveals Rora as a component of the mammalian circadian clock.
Neuron
2004
12657722
Protein kinase C delta is a prosurvival factor in human breast tumor cell lines.
Mol Cancer Ther
2003
14514886
Genome-scale functional profiling of the mammalian AP-1 signaling pathway.
Proc Natl Acad Sci U S A
2003
14506290
Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells.
Proc Natl Acad Sci U S A
2003
14536081
TORCs: transducers of regulated CREB activity.
Mol Cell
2003
11198929
Variations in mRNA content have no effect on the potency of antisense oligonucleotides.
Antisense Nucleic Acid Drug Dev
2000
10948199
Human RNase III is a 160-kDa protein involved in preribosomal RNA processing.
J Biol Chem
2000
10206071
Antisense oligonucleotides to the epidermal growth factor receptor.
Breast Cancer Res Treat
1999
10454217
Pharmacology of antisense oligonucleotide inhibitors of protein expression.
Pharmacol Ther
1999
9880552
Characterization of a potent and specific class of antisense oligonucleotide inhibitor of human protein kinase C-alpha expression.
J Biol Chem
1999
9236849
Antisense oligonucleotide inhibitors of isozymes of protein kinase C: in vitro and in vivo activity, and clinical development as anti-cancer therapeutics.
Anticancer Drug Des
1997
8758918
Inhibition of growth of human tumor cell lines in nude mice by an antisense of oligonucleotide inhibitor of protein kinase C-alpha expression.
Cancer Res
1996
8894802
Inhibition of interleukin-1 type I receptor expression in human cell-lines by an antisense phosphorothioate oligodeoxynucleotide.
Int J Immunopharmacol
1996
8878816
Antisense oligonucleotides as inhibitors of signal transduction: development from research tools to therapeutic agents.
Biochem Soc Trans
1996
1597477
Modulation of eucaryotic initiation factor-4E binding to 5'-capped oligoribonucleotides by modified anti-sense oligonucleotides.
J Biol Chem
1992
1871121
Limited functional equivalence of phylogenetic variation in small nuclear RNA: yeast U2 RNA with altered branchpoint complementarity inhibits splicing and produces a dominant lethal phenotype.
Proc Natl Acad Sci U S A
1991
1 - 45 of 45
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3
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Paul-Ehrlich-Institut
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The Salk Institute for Biological Studies
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