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Author Details

Loren Miraglia
Genomics Institute of the Novartis Research Foundation
1991
45
29
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
33443164A genome-wide microRNA screen identifies the microRNA-183/96/182 cluster as a modulator of circadian rhythms.Proc Natl Acad Sci U S A2021
34526658EndoBind detects endogenous protein-protein interactions in real time.Commun Biol2021
29671265Making It All Work: Functional Genomics and Reporter Gene Assays.Methods Mol Biol2018
30297964Guide Swap enables genome-scale pooled CRISPR-Cas9 screening in human primary cells.Nat Methods2018
29671267Reporter Gene Assays Using Viral Functional Genomics Libraries.Methods Mol Biol2018
29671266Reporter Gene Assays Using Transfectable Functional Genomics Libraries.Methods Mol Biol2018
28068668The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERα.Nature2017
28569745The microprotein Minion controls cell fusion and muscle formation.Nat Commun2017
27649498High Throughput Random Mutagenesis and Single Molecule Real Time Sequencing of the Muscle Nicotinic Acetylcholine Receptor.PLoS One2016
27610566Domestication and Divergence of Saccharomyces cerevisiae Beer Yeasts.Cell2016
25616511Genome-Engineering Tools to Establish Accurate Reporter Cell Lines That Enable Identification of Therapeutic Strategies to Treat Friedreich's Ataxia.J Biomol Screen2015
24725410SWELL1, a plasma membrane protein, is an essential component of volume-regulated anion channel.Cell2014
24886841High throughput mutagenesis for identification of residues regulating human prostacyclin (hIP) receptor expression and function.PLoS One2014
23603119Akt-mediated phosphorylation of argonaute 2 downregulates cleavage and upregulates translational repression of MicroRNA targets.Mol Cell2013
22423970Cofactors required for TLR7- and TLR9-dependent innate immune responses.Cell Host Microbe2012
21564017Seeing the light: luminescent reporter gene assays.Comb Chem High Throughput Screen2011
21949408Tumor suppressor protein (p)53, is a regulator of NF-kappaB repression by the glucocorticoid receptor.Proc Natl Acad Sci U S A2011
20027183Human host factors required for influenza virus replication.Nature2010
20696907Identification of RING finger protein 4 (RNF4) as a modulator of DNA demethylation through a functional genomics screen.Proc Natl Acad Sci U S A2010
20085741An RNAi screen identifies TRRAP as a regulator of brain tumor-initiating cell differentiation.Cell Stem Cell2010
19340300A functional screen for regulators of CKDN2A reveals MEOX2 as a transcriptional activator of INK4a.PLoS One2009
19765810A genome-wide RNAi screen for modifiers of the circadian clock in human cells.Cell2009
19805117A genomic screen identifies TYRO3 as a MITF regulator in melanoma.Proc Natl Acad Sci U S A2009
18854154Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication.Cell2008
18077367A coactivator trap identifies NONO (p54nrb) as a component of the cAMP-signaling pathway.Proc Natl Acad Sci U S A2007
17939994A role for IkappaB kinase 2 in bipolar spindle assembly.Proc Natl Acad Sci U S A2007
16474406Feedback repression is required for mammalian circadian clock function.Nat Genet2006
17001007Genome-wide functional analysis of human cell-cycle regulators.Proc Natl Acad Sci U S A2006
17110210High-content screening of functional genomic libraries.Methods Enzymol2006
15312651A functional genomics strategy reveals Rora as a component of the mammalian circadian clock.Neuron2004
12657722Protein kinase C delta is a prosurvival factor in human breast tumor cell lines.Mol Cancer Ther2003
14514886Genome-scale functional profiling of the mammalian AP-1 signaling pathway.Proc Natl Acad Sci U S A2003
14506290Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells.Proc Natl Acad Sci U S A2003
14536081TORCs: transducers of regulated CREB activity.Mol Cell2003
11198929Variations in mRNA content have no effect on the potency of antisense oligonucleotides.Antisense Nucleic Acid Drug Dev2000
10948199Human RNase III is a 160-kDa protein involved in preribosomal RNA processing.J Biol Chem2000
10206071Antisense oligonucleotides to the epidermal growth factor receptor.Breast Cancer Res Treat1999
10454217Pharmacology of antisense oligonucleotide inhibitors of protein expression.Pharmacol Ther1999
9880552Characterization of a potent and specific class of antisense oligonucleotide inhibitor of human protein kinase C-alpha expression.J Biol Chem1999
9236849Antisense oligonucleotide inhibitors of isozymes of protein kinase C: in vitro and in vivo activity, and clinical development as anti-cancer therapeutics.Anticancer Drug Des1997
8758918Inhibition of growth of human tumor cell lines in nude mice by an antisense of oligonucleotide inhibitor of protein kinase C-alpha expression.Cancer Res1996
8894802Inhibition of interleukin-1 type I receptor expression in human cell-lines by an antisense phosphorothioate oligodeoxynucleotide.Int J Immunopharmacol1996
8878816Antisense oligonucleotides as inhibitors of signal transduction: development from research tools to therapeutic agents.Biochem Soc Trans1996
1597477Modulation of eucaryotic initiation factor-4E binding to 5'-capped oligoribonucleotides by modified anti-sense oligonucleotides.J Biol Chem1992
1871121Limited functional equivalence of phylogenetic variation in small nuclear RNA: yeast U2 RNA with altered branchpoint complementarity inhibits splicing and produces a dominant lethal phenotype.Proc Natl Acad Sci U S A1991
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Collaborators

Genomics Institute of the Novartis Research Foundation
Co-authored papers 19
The Scripps Research Institute
Co-authored papers 9
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 6
Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Co-authored papers 6
Prestige BioPharma Ltd
Co-authored papers 4
Keck School of Medicine, University of Southern California
Co-authored papers 4
Genomics Institute of the Novartis Research Foundation
Co-authored papers 4
United States Army Medical Research Institute of Infectious Diseases
Co-authored papers 3
Co-authored papers 3
Genomics Institute of the Novartis Research Foundation
Co-authored papers 3
Paul-Ehrlich-Institut
Co-authored papers 2
The Salk Institute for Biological Studies
Co-authored papers 2
University of California San Diego
Co-authored papers 2
Sirna Therapeutics a former subsidiary of Merck & Co., Inc.
Co-authored papers 2
Roche Pharma
Co-authored papers 2
Co-authored papers 2
Sanford-Burnham Medical Research Institute
Co-authored papers 2
Co-authored papers 2
University of California San Francisco
Co-authored papers 2
and the Center for Chronobiology, University of California at San Diego
Co-authored papers 1
Huntsman Cancer Institute at the University of Utah
Co-authored papers 1
NYU Grossman School of Medicine
Co-authored papers 1
Merck & Co., Inc.
Co-authored papers 1
university of california san diego School of Medicine
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
Howard Hughes Medical Institute
Co-authored papers 1
Institute of Molecular Genetics of the Czech Academy of Sciences
Co-authored papers 1
The Scripps Research Institute
Co-authored papers 1