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Author Details

Christopher A Koczor
Mitchell Cancer Institute, University of South Alabama
2009
26
14
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36702010Polβ/XRCC1 heterodimerization dictates DNA damage recognition and basal Polβ protein levels without interfering with mouse viability or fertility.DNA Repair (Amst)2023
37220749A multi-scale map of protein assemblies in the DNA damage response.Cell Syst2023
36515828Quantitative Analysis of Nuclear Poly(ADP-Ribose) Dynamics in Response to Laser-Induced DNA Damage.Methods Mol Biol2023
35892832Overcoming Temozolomide Resistance in Glioblastoma via Enhanced NAD<sup>+</sup> Bioavailability and Inhibition of Poly-ADP-Ribose Glycohydrolase.Cancers (Basel)2022
35954352Live Cell Detection of Poly(ADP-Ribose) for Use in Genetic and Genotoxic Compound Screens.Cancers (Basel)2022
34806016NAD<sup>+</sup> bioavailability mediates PARG inhibition-induced replication arrest, intra S-phase checkpoint and apoptosis in glioma stem cells.NAR Cancer2021
34731617Temporal dynamics of base excision/single-strand break repair protein complex assembly/disassembly are modulated by the PARP/NAD<sup>+</sup>/SIRT6 axis.Cell Rep2021
33087267NAD<sup>+</sup>-mediated regulation of mammalian base excision repair.DNA Repair (Amst)2020
31287140Stability and sub-cellular localization of DNA polymerase β is regulated by interactions with NQO1 and XRCC1 in response to oxidative stress.Nucleic Acids Res2019
29408195Hydrogen sulfide regulates cardiac mitochondrial biogenesis via the activation of AMPK.J Mol Cell Cardiol2018
26757797Mitochondrial polymerase gamma dysfunction and aging cause cardiac nuclear DNA methylation changes.Physiol Genomics2016
26199398AZT-induced mitochondrial toxicity: an epigenetic paradigm for dysregulation of gene expression through mitochondrial oxidative stress.Physiol Genomics2015
26251327Ecstasy (MDMA) Alters Cardiac Gene Expression and DNA Methylation: Implications for Circadian Rhythm Dysfunction in the Heart.Toxicol Sci2015
26549358Connective tissue growth factor regulates cardiac function and tissue remodeling in a mouse model of dilated cardiomyopathy.J Mol Cell Cardiol2015
26307267Methamphetamine and HIV-Tat alter murine cardiac DNA methylation and gene expression.Toxicol Appl Pharmacol2015
23090637Transgenic mouse model with deficient mitochondrial polymerase exhibits reduced state IV respiration and enhanced cardiac fibrosis.Lab Invest2013
23695887Thymidine kinase and mtDNA depletion in human cardiomyopathy: epigenetic and translational evidence for energy starvation.Physiol Genomics2013
23695888Detection of differentially methylated gene promoters in failing and nonfailing human left ventricle myocardium using computation analysis.Physiol Genomics2013
23499753Mitochondrial matrix P53 sensitizes cells to oxidative stress.Mitochondrion2013
22469844p53 and mitochondrial DNA: their role in mitochondrial homeostasis and toxicity of antiretrovirals.Am J Pathol2012
22509856The role of transporters in the toxicity of nucleoside and nucleotide analogs.Expert Opin Drug Metab Toxicol2012
22527902Reproductive aging is associated with decreased mitochondrial abundance and altered structure in murine oocytes.J Assist Reprod Genet2012
20045731Transgenic mouse models of mitochondrial toxicity associated with HIV/AIDS and antiretrovirals.Methods2010
20929279Nucleoside reverse transcriptase inhibitor toxicity and mitochondrial DNA.Expert Opin Drug Metab Toxicol2010
19513678Targeting repair proteins to the mitochondria of mammalian cells through stable transfection, transient transfection, viral transduction, and TAT-mediated protein transduction.Methods Mol Biol2009
19840931Mitochondrial DNA damage initiates a cell cycle arrest by a Chk2-associated mechanism in mammalian cells.J Biol Chem2009
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Collaborators

Robert W Sobol
University of South Alabama
Co-authored papers 9
Jianfeng Li
Mitchell Cancer Institute, University of South Alabama
Co-authored papers 6
Eva K Lee
Co-authored papers 2
Maya Modak
Co-authored papers 1
Rachel Collier
University of California San Diego
Co-authored papers 1
Nathan A Yates
University of Pittsburgh School of Medicine
Co-authored papers 1
Fan Zheng
University of California San Diego
Co-authored papers 1
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 1
Jisoo Park
University of California San Diego san francisco
Co-authored papers 1
Dexter Pratt (CM4AI)
UC San Diego
Co-authored papers 1
Yue Qin
University of California San Diego
Co-authored papers 1
David J Lefer
Co-authored papers 1
Jing Chen
College of Bioinformatics Science and Technology, Harbin Medical University
Co-authored papers 1
Katherine Licon
University of California San Diego
Co-authored papers 1
Christopher Churas (CM4AI)
University of California San Diego
Co-authored papers 1
Anton Kratz
University of California San Diego san francisco
Co-authored papers 1
Rudolf T Pillich
University of California San Diego
Co-authored papers 1
Trey Ideker (CM4AI)
University of California San Diego
Co-authored papers 1
Keiichiro Ono
university of california san diego
Co-authored papers 1
Minkyu Kim
University of California san francisco
Co-authored papers 1
Marcus R Kelly
Stanford University School of Medicine
Co-authored papers 1
Release 1.2