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Author Details

Ralph Buttyan
University of British Columbia
1976
184
61
PMIDPaper TitleJournal TitlePublished Year
37126232Multimodal Biomarkers That Predict the Presence of Gleason Pattern 4: Potential Impact for Active Surveillance.J Urol2023
33347954Gli activation by the estrogen receptor in breast cancer cells: Regulation of cancer cell growth by Gli3.Mol Cell Endocrinol2021
34934057The long noncoding RNA H19 regulates tumor plasticity in neuroendocrine prostate cancer.Nat Commun2021
31919137Transient Sox9 Expression Facilitates Resistance to Androgen-Targeted Therapy in Prostate Cancer.Clin Cancer Res2020
31970695Erythropoietin promotes functional recovery via anti-apoptotic mechanisms in mouse unilateral ureteral obstruction.Cell Stress Chaperones2020
30510231Correction: A molecular portrait of epithelial-mesenchymal plasticity in prostate cancer associated with clinical outcome.Oncogene2019
30194451A molecular portrait of epithelial-mesenchymal plasticity in prostate cancer associated with clinical outcome.Oncogene2019
31445843The evolution of long noncoding RNA acceptance in prostate cancer initiation, progression, and its clinical utility in disease management.Eur Urol2019
31012113Inhibition of GLI2 with antisense-oligonucleotides: A potential therapy for the treatment of bladder cancer.J Cell Physiol2019
29429990Non-canonical activation of hedgehog in prostate cancer cells mediated by the interaction of transcriptionally active androgen receptor proteins with Gli3.Oncogene2018
29854872Hedgehog in prostate cancer explained.Oncoscience2018
30038724Correction: Implications of PI3K/AKT inhibition on REST protein stability and neuroendocrine phenotype acquisition in prostate cancer cells.Oncotarget2018
27672740Paracrine sonic hedgehog signaling contributes significantly to acquired steroidogenesis in the prostate tumor microenvironment.Int J Cancer2017
28188758A Role for the Hedgehog Effector Gli1 in Mediating Stent-induced Ureteral Smooth Muscle Dysfunction and Aperistalsis.Urology2017
28145883Therapy-induced developmental reprogramming of prostate cancer cells and acquired therapy resistance.Oncotarget2017
28092670Neuropilin-1 is upregulated in the adaptive response of prostate tumors to androgen-targeted therapies and is prognostic of metastatic progression and patient mortality.Oncogene2017
29156689Implications of PI3K/AKT inhibition on REST protein stability and neuroendocrine phenotype acquisition in prostate cancer cells.Oncotarget2017
28904399Semaphorin 3â¿¿C drives epithelial-to-mesenchymal transition, invasiveness, and stem-like characteristics in prostate cells.Sci Rep2017
26769750Not all NOTCH Is Created Equal: The Oncogenic Role of NOTCH2 in Bladder Cancer and Its Implications for Targeted Therapy.Clin Cancer Res2016
26036626Identification of novel genes that regulate androgen receptor signaling and growth of androgen-deprived prostate cancer cells.Oncotarget2015
26565916FOXC1 Activates Smoothened-Independent Hedgehog Signaling in Basal-like Breast Cancer.Cell Rep2015
24840332FOXA1 deletion in luminal epithelium causes prostatic hyperplasia and alteration of differentiated phenotype.Lab Invest2014
25132524Determinants of Gli2 co-activation of wildtype and naturally truncated androgen receptors.Prostate2014
23548616Role of androgen and vitamin D receptors in endothelial cells from benign and malignant human prostate.Am J Physiol Endocrinol Metab2013
23666965Expression and function of the progesterone receptor in human prostate stroma provide novel insights to cell proliferation control.J Clin Endocrinol Metab2013
22025366Paracrine Hedgehog increases the steroidogenic potential of prostate stromal cells in a Gli-dependent manner.Prostate2012
22665497The stress response mediator ATF3 represses androgen signaling by binding the androgen receptor.Mol Cell Biol2012
21267466Effects of androgen receptor and androgen on gene expression in prostate stromal fibroblasts and paracrine signaling to prostate cancer cells.PLoS One2011
22067658Networks of intergenic long-range enhancers and snpRNAs drive castration-resistant phenotype of prostate cancer and contribute to pathogenesis of multiple common human disorders.Cell Cycle2011
21776292The hedgehog/Gli signaling paradigm in prostate cancer.Expert Rev Endocrinol Metab2011
21746916Tumor-specific silencing of COPZ2 gene encoding coatomer protein complex subunit ζ 2 renders tumor cells dependent on its paralogous gene COPZ1.Proc Natl Acad Sci U S A2011
20420697Hedgehog/Gli supports androgen signaling in androgen deprived and androgen independent prostate cancer cells.Mol Cancer2010
21045157Class III beta-tubulin expression predicts prostate tumor aggressiveness and patient response to docetaxel-based chemotherapy.Cancer Res2010
20488474Gli2 expression and human bladder transitional carcinoma cell invasiveness.J Urol2010
19158486Androgenic regulation of hedgehog signaling pathway components in prostate cancer cells.Cell Cycle2009
19690549Increased expression of class III beta-tubulin in castration-resistant human prostate cancer.Br J Cancer2009
19375749Differential expression of vascular endothelial growth factor, and angiopoietin 1 and 2 in functionally divergent experimental rabbit models of bladder hypertrophy.J Urol2009
19476740beta-carboline alkaloid-enriched extract from the amazonian rain forest tree pao pereira suppresses prostate cancer cells.J Soc Integr Oncol2009
18262714Editorial comment on: Hedgehog signalling in androgen independent prostate cancer.Eur Urol2008
17437767Molecularly targeted therapies for renal cell cancer: TRAIL research advances.J Urol2007
17691963The Wnt/beta-catenin pathway in Wilms tumors and prostate cancers.Curr Mol Med2007
17343803Dietary agents/supplements hit the clinic for prostate cancer chemoprevention.Discov Med2007
16698354Detection of carbonic anhydrase-9 gene expression in peripheral blood cells predicts risk of disease recurrence in patients with renal cortical tumors.Urology2006
16989596Clinical trials of natural products as chemopreventive agents for prostate cancer.Expert Opin Investig Drugs2006
17016636Anti-prostate cancer activity of a beta-carboline alkaloid enriched extract from Rauwolfia vomitoria.Int J Oncol2006
16741972Multifaceted interaction between the androgen and Wnt signaling pathways and the implication for prostate cancer.J Cell Biochem2006
16474850Complex regulation of human androgen receptor expression by Wnt signaling in prostate cancer cells.Oncogene2006
16637074Protocadherin-PC promotes androgen-independent prostate cancer cell growth.Prostate2006
16630519The use of herbal and over-the-counter dietary supplements for the prevention of prostate cancer.Curr Urol Rep2006
16618388The use of herbal and over-the-counter dietary supplements for the prevention of prostate cancer.Curr Oncol Rep2006
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Collaborators

Mark A Rubin
University of Bern
Co-authored papers 13
Martin E Gleave
University of British Columbia
Co-authored papers 8
Ladan Fazli
University of British Columbia
Co-authored papers 7
Vivette D D'Agati
Columbia University Irving Medical Center
Co-authored papers 6
Colin C Collins
University of British Columbia
Co-authored papers 4
Elai Davicioni
Veracyte Inc.
Co-authored papers 4
Daniel F Heitjan
Co-authored papers 4
Yuzhuo Wang
University of British Columbia
Co-authored papers 3
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Mayo Clinic
Co-authored papers 3
Kenneth Walsh
University of Virginia School of Medicine
Co-authored papers 3
Varune R Ramnarine
University of British Columbia
Co-authored papers 3
Manisha Desai
Stanford University
Co-authored papers 2
Nicholas Erho
GenomeDx Biosciences Inc.
Co-authored papers 2
Mandeep Takhar
GenomeDx Biosciences Inc.
Co-authored papers 2
Amina Zoubeidi
University of British Columbia
Co-authored papers 2
Chenwei Wang
Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University
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V Venkateswaran
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A Thomson
McGill University and the Research Institute of the McGill University Health Centre
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Piali Mukherjee
Co-authored papers 1
Eric J Small
University of California san francisco
Co-authored papers 1
Andrew Loblaw
Princess Margaret Hospital, University of Toronto
Co-authored papers 1
Glenn Bauman
Western University and London Regional Cancer Program
Co-authored papers 1
Shawn M Chevalier
McGill University and the Research Institute of the McGill University Health Centre
Co-authored papers 1
Hui Xue
Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences
Co-authored papers 1
David M Berman
Queen's University
Co-authored papers 1
Mohammed Alshalalfa
University of Miami Miller School of Medicine/Sylvester Comprehensive Cancer Center
Co-authored papers 1
Fadi Brimo
McGill University Health Centre, McGill University
Co-authored papers 1
Shikha Bose
Co-authored papers 1
Nadia Boufaied
Research Institute of the McGill University Health Centre
Co-authored papers 1
Mahesh Mansukhani
Co-authored papers 1
Release 1.2