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Author Details

Jeffrey R Whiteaker
2002
76
36
PMIDPaper TitleJournal TitlePublished Year
37541199Proteogenomic analysis of chemo-refractory high-grade serous ovarian cancer.Cell2023
36259971Intraventricular B7-H3 CAR T Cells for Diffuse Intrinsic Pontine Glioma: Preliminary First-in-Human Bioactivity and Safety.Cancer Discov2023
37730181Clinical Proteomics for Solid Organ Tissues.2023
37643636Hormone Receptor-Positive Breast Cancer Sensitive to Pembrolizumab: Evidence of the Pathogenicity of the MLH1 Variant 1835del3.2023
37478973Monitoring Both Extended and Tryptic Forms of Stable Isotope-Labeled Standard Peptides Provides an Internal Quality Control of Proteolytic Digestion in Targeted Mass Spectrometry-Based Assays.2023
36912284Fanconi anemia-isogenic head and neck cancer cell line pairs: A basic and translational science resource.Int J Cancer2023
37273420Phase I/II results of ceralasertib as monotherapy or in combination with acalabrutinib in high-risk relapsed/refractory chronic lymphocytic leukemia.2023
37205196A multiplexed assay for quantifying immunomodulatory proteins supports correlative studies in immunotherapy clinical trials.Front Oncol2023
36301140Preserving the Phosphoproteome of Clinical Biopsies Using a Quick-Freeze Collection Device.Biopreserv Biobank2022
35767427Internal Standard Triggered-Parallel Reaction Monitoring Mass Spectrometry Enables Multiplexed Quantification of Candidate Biomarkers in Plasma.Anal Chem2022
34359745Targeted Mass Spectrometry Enables Quantification of Novel Pharmacodynamic Biomarkers of ATM Kinase Inhibition.Cancers (Basel)2021
33568520Loss of TGFβ signaling increases alternative end-joining DNA repair that sensitizes to genotoxic therapies across cancer types.Science Translational Medicine2021
34136904Quantification of Human Epidermal Growth Factor Receptor 2 by Immunopeptide Enrichment and Targeted Mass Spectrometry in Formalin-Fixed Paraffin-Embedded and Frozen Breast Cancer Tissues.Clin Chem2021
34858420Targeted Mass Spectrometry Enables Multiplexed Quantification of Immunomodulatory Proteins in Clinical Biospecimens.Front Immunol2021
34671754Targeted mass spectrometry-based assays enable multiplex quantification of receptor tyrosine kinase, MAP Kinase, and AKT signaling.Cell Rep Methods2021
35028612Multiomic analysis identifies CPT1A as a potential therapeutic target in platinum-refractory, high-grade serous ovarian cancer.Cell Rep Med2021
34429382Comparative analysis of TCR and CAR signaling informs CAR designs with superior antigen sensitivity and in vivo function.Sci Signal2021
33106847Quantification of Estrogen Receptor, Progesterone Receptor, and Human Epidermal Growth Factor Receptor 2 Protein Expression in Bone Biopsies by Targeted Mass Spectrometry without Acid Decalcification.Clinical Chemistry2020
32296420Multiplexed Proteomic Analysis for Diagnosis and Screening of Five Primary Immunodeficiency Disorders From Dried Blood Spots.Frontiers in Immunology2020
32575471Identification of a Blood-Based Protein Biomarker Panel for Lung Cancer Detection.Cancers (Basel)2020
31467290A dataset describing a suite of novel antibody reagents for the RAS signaling network.Sci Data2019
30487530Clinical potential of mass spectrometry-based proteogenomics.Nat Rev Clin Oncol2019
29605812Targeted mass spectrometry enables robust quantification of FANCD2 mono-ubiquitination in response to DNA damage.DNA Repair (Amst)2018
30385821pRAD50: a novel and clinically applicable pharmacodynamic biomarker of both ATM and ATR inhibition identified using mass spectrometry and immunohistochemistry.Br J Cancer2018
30131370Phosphoproteomic analysis of chimeric antigen receptor signaling reveals kinetic and quantitative differences that affect cell function.Sci Signal2018
30564228Rapid Multiplexed Proteomic Screening for Primary Immunodeficiency Disorders From Dried Blood Spots.Frontiers in Immunology2018
29474155A Multiplexed Mass Spectrometry-Based Assay for Robust Quantification of Phosphosignaling in Response to DNA Damage.Radiat Res2018
27935710Quantification of ATP7B Protein in Dried Blood Spots by Peptide Immuno-SRM as a Potential Screen for Wilson's Disease.Journal of Proteome Research2017
28477121Peptide Immunoaffinity Enrichment with Targeted Mass Spectrometry: Application to Quantification of ATM Kinase Phospho-Signaling.Methods in Molecular Biology2017
27727212Quantifying the human proteome.Nature Biotechnology2016
27094115Commercially available antibodies can be applied in quantitative multiplexed peptide immunoaffinity enrichment targeted mass spectrometry assays.Proteomics2016
26867747Using the CPTAC Assay Portal to Identify and Implement Highly Characterized Targeted Proteomics Assays.Methods Mol Biol2016
26719571Recommendations for the Generation, Quantification, Storage, and Handling of Peptides Used for Mass Spectrometry-Based Assays.Clin Chem2016
27462933Optimized Protocol for Quantitative Multiple Reaction Monitoring-Based Proteomic Analysis of Formalin-Fixed, Paraffin-Embedded Tissues.Journal of Proteome Research2016
26621847Immobilized Metal Affinity Chromatography Coupled to Multiple Reaction Monitoring Enables Reproducible Quantification of Phospho-signaling.Mol Cell Proteomics2016
25987412Peptide Immunoaffinity Enrichment and Targeted Mass Spectrometry Enables Multiplex, Quantitative Pharmacodynamic Studies of Phospho-Signaling.Mol Cell Proteomics2015
25693799Large-Scale Interlaboratory Study to Develop, Analytically Validate and Apply Highly Multiplexed, Quantitative Peptide Assays to Measure Cancer-Relevant Proteins in Plasma.Mol Cell Proteomics2015
25512614Anti-peptide monoclonal antibodies generated for immuno-multiple reaction monitoring-mass spectrometry assays have a high probability of supporting Western blot and ELISA.Molecular and Cellular Proteomics2015
26302155Antibody-Coupled Magnetic Beads Can Be Reused in Immuno-MRM Assays To Reduce Cost and Extend Antibody Supply.Journal of Proteome Research2015
26121405Assessment of a method to characterize antibody selectivity and specificity for use in immunoprecipitation.Nat Methods2015
25102069Panorama: a targeted proteomics knowledge base.J Proteome Res2014
24317253Demonstrating the feasibility of large-scale development of standardized assays to quantify human proteins.Nat Methods2014
24568200High-affinity recombinant antibody fragments (Fabs) can be applied in peptide enrichment immuno-MRM assays.Journal of Proteome Research2014
24972168CPTAC Assay Portal: a repository of targeted proteomic assays.Nat Methods2014
22199228Interlaboratory evaluation of automated, multiplexed peptide immunoaffinity enrichment coupled to multiple reaction monitoring mass spectrometry for quantifying proteins in plasma.Mol Cell Proteomics2012
22577026Multiplexed quantification of estrogen receptor and HER2/Neu in tissue and cell lysates by peptide immunoaffinity enrichment mass spectrometry.Proteomics2012
22203691Sequential multiplexed analyte quantification using peptide immunoaffinity enrichment coupled to mass spectrometry.Mol Cell Proteomics2012
21685906A targeted proteomics-based pipeline for verification of biomarkers in plasma.Nat Biotechnol2011
21245105Evaluation of large scale quantitative proteomic assay development using peptide affinity-based mass spectrometry.Mol Cell Proteomics2011
21448875Proteome and transcriptome profiles of a Her2/Neu-driven mouse model of breast cancer.Proteomics Clin Appl2011
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