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Author Details

Daniel S Hitchcock
Broad Institute of MIT and Harvard
2010
14
11
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36991126Ornithine aminotransferase supports polyamine synthesis in pancreatic cancer.Nature2023
33653947Adaptation of pancreatic cancer cells to nutrient deprivation is reversible and requires glutamine synthetase stabilization by mTORC1.Proc Natl Acad Sci U S A2021
31969373A Prospective Analysis of Circulating Plasma Metabolites Associated with Ovarian Cancer Risk.Cancer Res2020
31071294Bacteroides-Derived Sphingolipids Are Critical for Maintaining Intestinal Homeostasis and Symbiosis.Cell Host Microbe2019
29610318Ablation of insulin receptor substrates 1 and 2 suppresses <i>Kras</i>-driven lung tumorigenesis.Proc Natl Acad Sci U S A2018
28071763Starved epithelial cells uptake extracellular matrix for survival.Nat Commun2017
28808255Critical role for arginase 2 in obesity-associated pancreatic cancer.Nat Commun2017
25559274Structure of N-formimino-L-glutamate iminohydrolase from Pseudomonas aeruginosa.Biochemistry2015
24791931Substrate deconstruction and the nonadditivity of enzyme recognition.J Am Chem Soc2014
25384249Discovery of a bacterial 5-methylcytosine deaminase.Biochemistry2014
23256477Assignment of pterin deaminase activity to an enzyme of unknown function guided by homology modeling and docking.J Am Chem Soc2013
23968233Structure-guided discovery of new deaminase enzymes.J Am Chem Soc2013
21604715Rescue of the orphan enzyme isoguanine deaminase.Biochemistry2011
20415463Discovery and structure determination of the orphan enzyme isoxanthopterin deaminase .Biochemistry2010
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Collaborators

Clary B Clish
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Co-authored papers 7
Frank M Raushel
Texas A&M University, College Station
Co-authored papers 7
Steven C Almo
Albert Einstein College of Medicine
Co-authored papers 6
Brian K Shoichet
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Co-authored papers 3
Andrej Sali (CM4AI)
University of California San Francisco
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Brandan Hillerich
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Ronald D Seidel
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Hao Fan
College of Biotechnology and Bioengineering, Zhejiang University of Technology
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Stephen K Burley
The State University of New Jersey
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Jeffery A Porter
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Bernard Rosner
Brigham and Women's Hospital and Harvard Medical School
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Ramnik J Xavier
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Aleksandar D Kostic
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J Michael Sauder
Eli Lilly and Co.
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Sarah Barelier
CNRS, Aix-Marseille University
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Karen N Allen
Boston University
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Jungwook Kim
Gwangju Institute of Science and Technology
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Rakhi Agarwal
National Forensic Sciences University
Co-authored papers 1
Curtis Huttenhower
Broad Institute of MIT and Harvard
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Subramanyam Swaminathan
Brookhaven National Laboratory
Co-authored papers 1
Henry Lin
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 1
Peter Kraft
Harvard T. H. Chan School of Public Health
Co-authored papers 1
Release 1.2