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Author Details

Marcus Fruttiger
UCL Institute of Ophthalmology
1995
104
50
PMIDPaper TitleJournal TitlePublished Year
35301216Intraretinal pigmented cells in retinal degenerative disease.Br J Ophthalmol2023
38067194Wnt/β-Catenin-Signaling Modulates Megakaryopoiesis at the Megakaryocyte-Erythrocyte Progenitor Stage in the Hematopoietic System.Cells2023
37367841Untargeted Metabolomic Analysis of Sjögren-Larsson Syndrome Reveals a Distinctive Pattern of Multiple Disrupted Biochemical Pathways.Metabolites2023
36997154Divergent amino acid and sphingolipid metabolism in patients with inherited neuro-retinal disease.Mol Metab2023
36745234Spatial distribution of metabolites in the retina and its relevance to studies of metabolic retinal disorders.Metabolomics2023
35837722Description of a patient cohort with Hereditary Sensory Neuropathy type 1 without retinal disease Macular Telangiectasia type 2 - implications for retinal screening in HSN1.J Peripher Nerv Syst2022
33640465VEGFR1 signaling in retinal angiogenesis and microinflammation.Prog Retin Eye Res2021
32347571RhoJ integrates attractive and repulsive cues in directional migration of endothelial cells.EMBO J2020
32053618Intravenous indocyanine green dye is insufficient for robust immune cell labelling in the human retina.PLoS One2020
32818114Longitudinal Assessment of Remnant Foveal Cone Structure in a Case Series of Early Macular Telangiectasia Type 2.Transl Vis Sci Technol2020
32699277Systemic lipid dysregulation is a risk factor for macular neurodegenerative disease.Sci Rep2020
32586743Macular Telangiectasia Type 2: Visual Acuity, Disease End Stage, and the MacTel Area: MacTel Project Report Number 8.Ophthalmology2020
31022297Dark-Adapted Two-Color Fundus-Controlled Perimetry in Macular Telangiectasia Type 2.Invest Ophthalmol Vis Sci2019
29858186Contrast sensitivity and visual acuity under low light conditions in macular telangiectasia type 2.Br J Ophthalmol2019
31529080Binocular Inhibition of Reading in Macular Telangiectasia Type 2.Invest Ophthalmol Vis Sci2019
31293809High-Resolution In Vivo Fundus Angiography using a Nonadaptive Optics Imaging System.Transl Vis Sci Technol2019
31509666Serine and Lipid Metabolism in Macular Disease and Peripheral Neuropathy.N Engl J Med2019
30790589p53 plays a crucial role in endothelial dysfunction associated with hyperglycemia and ischemia.J Mol Cell Cardiol2019
28654457EFFECT OF DARK ADAPTATION AND BLEACHING ON BLUE LIGHT REFLECTANCE IMAGING IN MACULAR TELANGIECTASIA TYPE 2.Retina2018
30518679Inhibition of stromal cell-derived factor-1α/CXCR4 signaling restores the blood-retina barrier in pericyte-deficient mouse retinas.JCI Insight2018
29766399Consensus guidelines for the use and interpretation of angiogenesis assays.Angiogenesis2018
29129724Retinal vasculature development in health and disease.Prog Retin Eye Res2018
29045321FUNDUS-WIDE SUBRETINAL AND PIGMENT EPITHELIAL ABNORMALITIES IN MACULAR TELANGIECTASIA TYPE 2.Retina2018
28834952MACULAR TELANGIECTASIA TYPE 2: Quantitative Analysis of a Novel Phenotype and Implications for the Pathobiology of the Disease.Retina2018
28644304ABNORMAL RETINAL REFLECTIVITY TO SHORT-WAVELENGTH LIGHT IN TYPE 2 IDIOPATHIC MACULAR TELANGIECTASIA.Retina2018
28654458ELECTROPHYSIOLOGICAL CHARACTERIZATION OF MACULAR TELANGIECTASIA TYPE 2 AND STRUCTURE-FUNCTION CORRELATION.Retina2018
28846772Conditional Müller Cell Ablation Leads to Retinal Iron Accumulation.Invest Ophthalmol Vis Sci2017
28107458Neuropilin 1 Involvement in Choroidal and Retinal Neovascularisation.PLoS One2017
28250457Genome-wide analyses identify common variants associated with macular telangiectasia type 2.Nat Genet2017
28445461Tumour ischaemia by interferon-γ resembles physiological blood vessel regression.Nature2017
28973878YAP/TAZ-CDC42 signaling regulates vascular tip cell migration.Proc Natl Acad Sci U S A2017
26974308Retinal lipid and glucose metabolism dictates angiogenesis through the lipid sensor Ffar1.Nat Med2016
27702771Endothelial FAK is required for tumour angiogenesis.EMBO Mol Med2016
27661854Evaluation of Nonperfused Retinal Vessels in Ischemic Retinopathy.Invest Ophthalmol Vis Sci2016
27270778Corrigendum: Retinal lipid and glucose metabolism dictates angiogenesis through the lipid sensor Ffar1.Nat Med2016
27558877Pleiotropic action of CpG-ODN on endothelium and macrophages attenuates angiogenesis through distinct pathways.Sci Rep2016
27445154Diverse Functions of Retinoic Acid in Brain Vascular Development.J Neurosci2016
26735015FOXO1 couples metabolic activity and growth state in the vascular endothelium.Nature2016
25284762Reevaluating the definition of intraretinal microvascular abnormalities and neovascularization elsewhere in diabetic retinopathy using optical coherence tomography and fluorescein angiography.Am J Ophthalmol2015
26398933A simple method for in vivo labelling of infiltrating leukocytes in the mouse retina using indocyanine green dye.Dis Model Mech2015
26081042Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch.Nat Commun2015
26228240PTEN mediates Notch-dependent stalk cell arrest in angiogenesis.Nat Commun2015
26226015Intravitreally Injected Anti-VEGF Antibody Reduces Brown Fat in Neonatal Mice.PLoS One2015
25772358cKit Lineage Hemogenic Endothelium-Derived Cells Contribute to Mesenteric Lymphatic Vessels.Cell Rep2015
25605522Suppression of transient receptor potential canonical channel 4 inhibits vascular endothelial growth factor-induced retinal neovascularization.Cell Calcium2015
25613127Diabetic macular ischaemia is associated with narrower retinal arterioles in patients with type 2 diabetes.Acta Ophthalmol2015
24025642Selective deletion of the endothelial sphingosine-1-phosphate 1 receptor exacerbates kidney ischemia-reperfusion injury.Kidney Int2014
25198863The ubiquitin ligase PDZRN3 is required for vascular morphogenesis through Wnt/planar cell polarity signalling.Nat Commun2014
25057989A crucial role for CDC42 in senescence-associated inflammation and atherosclerosis.PLoS One2014
24896812Endothelial depletion of Acvrl1 in mice leads to arteriovenous malformations associated with reduced endoglin expression.PLoS One2014
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Collaborators

Catherine Egan
Moorfields Eye Hospital NHS Foundation Trust
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Tjebo F C Heeren
Moorfields Eye Hospital, NHS Foundation Trust
Co-authored papers 13
Dawn A Sim
Institute of Ophthalmology, University College London
Co-authored papers 12
Adnan Tufail
Moorfields Eye Hospital NHS Foundation Trust
Co-authored papers 11
Mark C Gillies
The University of Sydney Save Sight Institute
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Pearse A Keane
Moorfields Eye Hospital NHS Foundation Trust
Co-authored papers 9
Mali Okada
Royal Victorian Eye and Ear Hospital
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Martin Friedlander
the Scripps Research Institute
Co-authored papers 7
Melanie Bahlo
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Peter Charbel Issa
Oxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust
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Marin L Gantner
Lowy Medical Research Institute
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Praveen J Patel
NIHR Moorfields Biomedical Research Centre
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Javier Zarranz-Ventura
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Kari Alitalo
Wihuri Research Institute
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Robyn H Guymer
Royal Victorian Eye and Ear Hospital, the University of Melbourne
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Frank G Holz
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Rando Allikmets
Columbia University Medical Center
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Paul S Bernstein
University of Utah
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Edith Aguilar
the Scripps Research Institute
Co-authored papers 2
Hemal Mehta
The University of Sydney Save Sight Institute
Co-authored papers 2
Traci E Clemons
The EMMES Corporation
Co-authored papers 2
Maddy Parsons
Co-authored papers 2
Michal K Handzlik
The Salk Institute for Biological Studies
Co-authored papers 2
Tunde Peto
Queen's University Belfast
Co-authored papers 2
Catey Bunce
Royal Marsden NHS Foundation Trust
Co-authored papers 2
Fran??ois-Michel Boisvert
Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke (CRCHUS)
Co-authored papers 2
Clary B Clish
Broad Institute of MIT and Harvard
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Peter M Maloca
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Lea Scheppke
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