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Author Details

Thomas A Frenkiel
The Medical Research Council Biomedical NMR Centre, The Francis Crick Institute
1984
64
25
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35738429CP-MAS and Solution NMR Studies of Allosteric Communication in CA-assemblies of HIV-1.J Mol Biol2022
30997945Cross-Peaks in Simple Two-Dimensional NMR Experiments from Chemical Exchange of Transverse Magnetisation.Angew Chem Int Ed Engl2019
28252051Determination of the pK<sub>a</sub> of the N-terminal amino group of ubiquitin by NMR.Sci Rep2017
22253442Solution structure of homology region (HR) domain of type II secretion system.J Biol Chem2012
22955930In support of the BMRB.Nat Struct Mol Biol2012
19198587Phosphorylation-mediated unfolding of a KH domain regulates KSRP localization via 14-3-3 binding.Nat Struct Mol Biol2009
17180445NMR assignment of the leucine-rich repeat domain of LANP/Anp32a.J Biomol NMR2007
16540468Structural diversity in p160/CREB-binding protein coactivator complexes.J Biol Chem2006
16821126NMR assignment of peptidyl-tRNA hydrolase from Mycobacterium tuberculosis H37Rv.J Biomol NMR2006
16518566NMR assignment and secondary structure determination of the C-terminal MA-3 domain of the tumour suppressor protein Pdcd4.J Biomol NMR2006
16407062The structure of the N-terminal domain of the fragile X mental retardation protein: a platform for protein-protein interaction.Structure2006
15641776Precise epitope mapping of malaria parasite inhibitory antibodies by TROSY NMR cross-saturation.Biochemistry2005
16222560Solution structure of human dihydrofolate reductase in its complex with trimethoprim and NADPH.J Biomol NMR2005
15933069Specificity and mechanism of the histone methyltransferase Pr-Set7.Genes Dev2005
15929005Backbone assignment of PCF11 CTD binding domain.J Biomol NMR2005
15973432Structure and function of the complex formed by the tuberculosis virulence factors CFP-10 and ESAT-6.EMBO J2005
14872137Assignment of the 1H, 13C, and 15N resonances of the AXH domain of the transcription factor HBP1.J Biomol NMR2004
15630566Assignment of the 1H, 13C, and 15N resonances of the Josephin domain of human ataxin-3.J Biomol NMR2004
15557808Sequence-specific assignment and secondary structure determination of the 195-residue complex formed by the Mycobacterium tuberculosis proteins CFP-10 and ESAT-6.J Biomol NMR2004
15500913Malaria parasite-inhibitory antibody epitopes on Plasmodium falciparum merozoite surface protein-1(19) mapped by TROSY NMR.Mol Biochem Parasitol2004
12564929NMR structure of the DNA-binding domain of the cell cycle protein Mbp1 from Saccharomyces cerevisiae.Biochemistry2003
14512742NMR assignment of the 1H, 15N and 13C resonances of the E. coli frataxin orthologue, CyaY.J Biomol NMR2003
12917404Solution structure of the Mycobacterium tuberculosis complex protein MPB70: from tuberculosis pathogenesis to inherited human corneal desease.J Biol Chem2003
12914917Domain architecture of the polyglutamine protein ataxin-3: a globular domain followed by a flexible tail.FEBS Lett2003
12404632Binding of sucrose octasulphate to the C-type lectin-like domain of the recombinant natural killer cell receptor NKR-P1A observed by NMR spectroscopy.Chembiochem2002
11697728Solution structure, hydrodynamics and thermodynamics of the UvrB C-terminal domain.J Biomol Struct Dyn2001
11727976Determining binding sites in protein-nucleic acid complexes by cross-saturation.J Biomol NMR2001
11573089Ca2+-independent binding of an EF-hand domain to a novel motif in the alpha-actinin-titin complex.Nat Struct Biol2001
10805125The influence of DNA binding on the backbone dynamics of the yeast cell-cycle protein Mbp1.J Biomol NMR2000
10903947Towards a structural understanding of Friedreich's ataxia: the solution structure of frataxin.Structure2000
10805138Assignment of the 1H, 13C and 15N resonances of the C-terminal EF-hands of alpha-actinin in a 14 kDa complex with Z-repeat 7 of titin.J Biomol NMR2000
10549137Assignment of the 1H, 15N, and 13C resonances of the C-terminal domain of frataxin, the protein responsible for Friedreich ataxia.J Biomol NMR1999
103532011H, 15N and 13C assignments of the DNA binding domain of transcription factor Mbp1 from S. cerevisiae in both its free and the DNA bound forms, and 1H assignments of the free DNA.J Biomol NMR1999
10339410Solution structure of an EGF module pair from the Plasmodium falciparum merozoite surface protein 1.J Mol Biol1999
10091649Structure and dynamics in solution of the complex of Lactobacillus casei dihydrofolate reductase with the new lipophilic antifolate drug trimetrexate.Protein Sci1999
10550692Identification of platination sites on human serum transferrin using (13)C and (15)N NMR spectroscopy.J Biol Inorg Chem1999
9705310High resolution structure of the N-terminal domain of tissue inhibitor of metalloproteinases-2 and characterization of its interaction site with matrix metalloproteinase-3.J Biol Chem1998
9514736The solution structure of the complex of Lactobacillus casei dihydrofolate reductase with methotrexate.J Mol Biol1998
9657674Solution structure of the B-Myb DNA-binding domain: a possible role for conformational instability of the protein in DNA binding and control of gene expression.Biochemistry1998
9094416Correlated bond rotations in interactions of arginine residues with ligand carboxylate groups in protein ligand complexes.FEBS Lett1997
9215577Trp128Tyr mutation in the N-lobe of recombinant human serum transferrin: 1H- and 15N-NMR and metal binding studies.Protein Eng1997
9424315Applying excitation sculpting to construct singly and doubly selective 1D NMR experiments.J Magn Reson1997
9374866Mapping the binding site for matrix metalloproteinase on the N-terminal domain of the tissue inhibitor of metalloproteinases-2 by NMR chemical shift perturbation.Biochemistry1997
9048890Hydration and solution structure of d(CGCAAATTTGCG)2 and its complex with propamidine from NMR and molecular modelling.Biochim Biophys Acta1997
9096235High-resolution solution structure of human pNR-2/pS2: a single trefoil motif protein.J Mol Biol1997
8654422Structure of the B-Myb DNA-binding domain in solution and evidence for multiple conformations in the region of repeat-2 involved in DNA binding: implications for sequence-specific DNA binding by Myb proteins.Eur J Biochem1996
8681955NMR detection of arginine-ligand interactions in complexes of Lactobacillus casei dihydrofolate reductase.Eur J Biochem1996
8672464Interlobe communication in 13C-methionine-labeled human transferrin.Biochemistry1996
8639679Conformational studies on the selectin and natural killer cell receptor ligands sulfo- and sialyl-lacto-N-fucopentaoses (SuLNFPII and SLNFPII) using NMR spectroscopy and molecular dynamics simulations. Comparisons with the nonacidic parent molecule LNFPII.Biochemistry1996
7542984Determination of stereospecific assignments, torsion-angle constraints, and rotamer populations in proteins using the program AngleSearch.J Magn Reson B1995
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Collaborators

Institute of Structural and Molecular Biology (ISMB), University College London
Co-authored papers 5
Leicester Institute of Structural and Chemical Biology, University of Leicester
Co-authored papers 4
Institute of Integrative Biology, University of Liverpool
Co-authored papers 2
The First Affiliated Hospital of Jinan University
Co-authored papers 2
University of Cambridge
Co-authored papers 2
University of Pittsburgh
Co-authored papers 2
King's College
Co-authored papers 2
Harwell Science & Innovation Campus
Co-authored papers 2
University of California San Francisco
Co-authored papers 1
Technische Universitat Munchen (TUM)
Co-authored papers 1
University of Bristol
Co-authored papers 1
The University of Manchester
Co-authored papers 1
Rutgers University
Co-authored papers 1
Center for Integrated Protein Science, Technische Universitat Munchen
Co-authored papers 1
University of Texas Southwestern Medical Center
Co-authored papers 1
The University of Sheffield
Co-authored papers 1
Institute of Systems, The University of Liverpool
Co-authored papers 1
University of Melbourne, The Royal Children's Hospital
Co-authored papers 1
Columbia University
Co-authored papers 1
Co-authored papers 1
National Institutes of Health
Co-authored papers 1
Zernike Institute for Advanced Materials, University of Groningen
Co-authored papers 1
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University of Oxford
Co-authored papers 1
University of Cambridge
Co-authored papers 1
Carnegie Mellon University
Co-authored papers 1
Imperial College London
Co-authored papers 1
Carnegie Mellon University
Co-authored papers 1
Institute for Protein Research, Osaka University
Co-authored papers 1
Sichuan University
Co-authored papers 1