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Author Details

John D McPherson
Ontario Institute for Cancer Research
1986
153
67
PMIDPaper TitleJournal TitlePublished Year
37337105Transcriptomic classes of BCR-ABL1 lymphoblastic leukemia.Nat Genet2023
31435024Cryptic genomic lesions in adverse-risk acute myeloid leukemia identified by integrated whole genome and transcriptome sequencing.Leukemia2020
32686686Landscape of somatic single nucleotide variants and indels in colorectal cancer and impact on survival.Nat Commun2020
30478095Future Promises and Concerns of Ubiquitous Next-Generation Sequencing.Cold Spring Harb Perspect Med2019
35100692Identification of Distinct Prognostic Groups: Implications for Patient Selection to Targeted Therapies Among Anti-Endocrine Therapy-Resistant Early Breast Cancers.JCO Precis Oncol2019
31511937Comparative toxicoproteogenomics of mouse and rat liver identifies TCDD-resistance genes.Arch Toxicol2019
31591588Genome-wide germline correlates of the epigenetic landscape of prostate cancer.Nat Med2019
30837567Regional perturbation of gene transcription is associated with intrachromosomal rearrangements and gene fusion transcripts in high grade ovarian cancer.Sci Rep2019
30923040Activation of hedgehog signaling associates with early disease progression in chronic lymphocytic leukemia.Blood2019
30478097Next-Generation Sequencing Technologies.Cold Spring Harb Perspect Med2019
30429608Sensitive tumour detection and classification using plasma cell-free DNA methylomes.Nature2018
35135130Minimally Invasive Real-Time Detection of Actionable Mutations in Patients With Metastatic Solid Tumors Using Fine-Needle and Liquid Biopsies.JCO Precis Oncol2018
29988082Prediction of acute myeloid leukaemia risk in healthy individuals.Nature2018
29954844Complex rearrangements and oncogene amplifications revealed by long-read DNA and RNA sequencing of a breast cancer cell line.Genome Res2018
27750381Molecular heterogeneity of non-small cell lung carcinoma patient-derived xenografts closely reflect their primary tumors.Int J Cancer2017
31015706Microscopy with ultraviolet surface excitation for rapid slide-free histology.Nat Biomed Eng2017
28481342Recurrent noncoding regulatory mutations in pancreatic ductal adenocarcinoma.Nat Genet2017
28273451Interrogation of Functional Cell-Surface Markers Identifies CD151 Dependency in High-Grade Serous Ovarian Cancer.Cell Rep2017
28939825Mitochondrial mutations drive prostate cancer aggression.Nat Commun2017
28659176ISOWN: accurate somatic mutation identification in the absence of normal tissue controls.Genome Med2017
28658204Tracing the origins of relapse in acute myeloid leukaemia to stem cells.Nature2017
27851734Erratum: A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns.Nature2017
27768182Association of Distinct Mutational Signatures With Correlates of Increased Immune Activity in Pancreatic Ductal Adenocarcinoma.JAMA Oncol2017
28068672Genomic hallmarks of localized, non-indolent prostate cancer.Nature2017
28067867Germline BRCA2 mutations drive prostate cancers with distinct evolutionary trajectories.Nat Commun2017
26859458Truncating Erythropoietin Receptor Rearrangements in Acute Lymphoblastic Leukemia.Cancer Cell2016
26546047Candidate DNA repair susceptibility genes identified by exome sequencing in high-risk pancreatic cancer.Cancer Lett2016
26541609Distinct routes of lineage development reshape the human blood hierarchy across ontogeny.Science2016
26590902Fine mapping of chromosome 5p15.33 based on a targeted deep sequencing and high density genotyping identifies novel lung cancer susceptibility loci.Carcinogenesis2016
27732578A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns.Nature2016
27184599Coming of age: ten years of next-generation sequencing technologies.Nat Rev Genet2016
26005866Spatial genomic heterogeneity within localized, multifocal prostate cancer.Nat Genet2015
26647970A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing.Nat Commun2015
26708082A cancer cell-line titration series for evaluating somatic classification.BMC Res Notes2015
25889765GLI2 inhibition abrogates human leukemia stem cell dormancy.J Transl Med2015
25888698Optimization of miRNA-seq data preprocessing.Brief Bioinform2015
24154973Identification of genes expressed by immune cells of the colon that are regulated by colorectal cancer-associated variants.Int J Cancer2014
25264775A defining decade in DNA sequencing.Nat Methods2014
25240283Hotspot activating PRKD1 somatic mutations in polymorphous low-grade adenocarcinomas of the salivary glands.Nat Genet2014
25049390Next-generation sequencing identifies rare variants associated with Noonan syndrome.Proc Natl Acad Sci U S A2014
25173705SeqControl: process control for DNA sequencing.Nat Methods2014
24825849Genomic support for a moa-tinamou clade and adaptive morphological convergence in flightless ratites.Mol Biol Evol2014
24962202Genomic testing in cancer: patient knowledge, attitudes, and expectations.Cancer2014
24522528Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia.Nature2014
24551080Use of Sequenom sample ID Plus® SNP genotyping in identification of FFPE tumor samples.PLoS One2014
24511469Antioxidant supplementation reduces genomic aberrations in human induced pluripotent stem cells.Stem Cell Reports2014
24728235A two-dimensional pooling strategy for rare variant detection on next-generation sequencing platforms.PLoS One2014
24646301ShatterProof: operational detection and quantification of chromothripsis.BMC Bioinformatics2014
24445778Robust global microRNA expression profiling using next-generation sequencing technologies.Lab Invest2014
24192544WaveCNV: allele-specific copy number alterations in primary tumors and xenograft models from next-generation sequencing.Bioinformatics2014
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Collaborators

Thomas J Hudson
Ontario Institute for Cancer Research
Co-authored papers 17
Lincoln Stein
Ontario Institute for Cancer Research, University Avenue
Co-authored papers 15
LaDeana W Hillier
University of Washington
Co-authored papers 15
Elaine R Mardis
The Ohio State University
Co-authored papers 15
Paul C Boutros
University of California los angeles
Co-authored papers 14
Richard K Wilson
The Ohio State University
Co-authored papers 14
Marco A Marra
University of British Columbia
Co-authored papers 13
Richard A Gibbs
Baylor College of Medicine
Co-authored papers 13
Lee Timms
Ontario Institute for Cancer Research, University Avenue
Co-authored papers 13
Timothy Beck
Human Longevity Inc.
Co-authored papers 12
Michelle Chan-Seng-Yue
Princess Margaret Cancer Centre
Co-authored papers 12
Andrew M K Brown
Ontario Institute for Cancer Research
Co-authored papers 12
Robert E Denroche
Ontario Institute for Cancer Research
Co-authored papers 11
Steven Gallinger
Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto
Co-authored papers 11
Quang M Trinh
Ontario Institute for Cancer Research
Co-authored papers 10
Lawrence E Heisler
Ontario Institute for Cancer Research
Co-authored papers 10
John E Dick
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 10
Donna M Muzny
Baylor College of Medicine
Co-authored papers 9
Michael Fraser
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 8
Eric D Green
National Human Genome Research Institute, National Institutes of Health
Co-authored papers 8
Richard de Borja
The Hospital for Sick Children
Co-authored papers 8
Lucinda Fulton
McDonnell Genome Institute, Washington University School of Medicine
Co-authored papers 8
Tina Graves
McDonnell Genome Institute, Washington University
Co-authored papers 8
Robert G Bristow
University of Toronto
Co-authored papers 8
Evan E Eichler
University of Washington
Co-authored papers 7
Ming-Sound Tsao
University Health Network, University of Toronto
Co-authored papers 7
Kazutoyo Osoegawa
Co-authored papers 7
Nicholas Buchner
Ontario Institute for Cancer Research
Co-authored papers 7
Faiyaz Notta
2Ontario Institute for Cancer Research
Co-authored papers 7
Pieter J de Jong
Center for Genetics, Children's Hospital Oakland Research Institute
Co-authored papers 7
Release 1.2