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Author Details

Tricia A Thornton-Wells
Inc., Department of Translational Medicine and Early-Stage Clinical Development
1997
45
22
PMIDPaper TitleJournal TitlePublished Year
36699961Electrophysiological biomarkers and age characterize phenotypic heterogeneity among individuals with major depressive disorder.Front Hum Neurosci2023
37842184Synaptic proteins in neuron-derived extracellular vesicles as biomarkers for Alzheimer's disease: novel methodology and clinical proof of concept.Extracell Vesicles Circ Nucl Acids2023
31273671Iron-regulatory genes are associated with Neuroimaging measures in HIV infection.Brain Imaging Behav2020
29377057Digital Therapeutics: An Integral Component of Digital Innovation in Drug Development.Clin Pharmacol Ther2018
28714976Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.Nat Genet2017
26092349Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk.Alzheimers Dement2016
26827652Discovery of gene-gene interactions across multiple independent data sets of late onset Alzheimer disease from the Alzheimer Disease Genetics Consortium.Neurobiol Aging2016
25531812Rarity of the Alzheimer disease-protective APP A673T variant in the United States.JAMA Neurol2015
26194614GSK3β Interactions with Amyloid Genes: An Autopsy Verification and Extension.Neurotox Res2015
25712025Resting-State Functional Connectivity in Individuals with Down Syndrome and Williams Syndrome Compared with Typically Developing Controls.Brain Connect2015
24026422Genetic interactions found between calcium channel genes modulate amyloid load measured by positron emission tomography.Hum Genet2014
25422929Neural correlates of amusia in williams syndrome.Brain Sci2014
25558465Impact of family structure and common environment on heritability estimation for neuroimaging genetics studies using Sequential Oligogenic Linkage Analysis Routines.J Med Imaging (Bellingham)2014
25199842Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.JAMA Neurol2014
25140149Genetic variation modifies risk for neurodegeneration based on biomarker status.Front Aging Neurosci2014
24922517Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.PLoS One2014
24713364Differences in age-related effects on brain volume in Down syndrome as compared to Williams syndrome and typical development.J Neurodev Disord2014
24656848Genetic modification of the relationship between phosphorylated tau and neurodegeneration.Alzheimers Dement2014
24077433Genetic interactions within inositol-related pathways are associated with longitudinal changes in ventricle size.J Alzheimers Dis2014
24112793Interactions between GSK3β and amyloid genes explain variance in amyloid burden.Neurobiol Aging2014
23107432Genetic interactions associated with 12-month atrophy in hippocampus and entorhinal cortex in Alzheimer's Disease Neuroimaging Initiative.Neurobiol Aging2013
24162737Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.Nat Genet2013
24244193Recurrent tissue-specific mtDNA mutations are common in humans.PLoS Genet2013
24260488Epistatic genetic effects among Alzheimer's candidate genes.PLoS One2013
23994450Associations between KCNJ6 (GIRK2) gene polymorphisms and pain-related phenotypes.Pain2013
23109214Inverse correspondence between hippocampal perfusion and verbal memory performance in older adults.Hippocampus2013
22008369White matter integrity deficits in prefrontal-amygdala pathways in Williams syndrome.Neuroimage2012
23102261The effect of intellectual ability on functional activation in a neurodevelopmental disorder: preliminary evidence from multiple fMRI studies in Williams syndrome.J Neurodev Disord2012
22459439Effect of nonrigid registration algorithms on deformation-based morphometry: a comparative study with control and Williams syndrome subjects.Magn Reson Imaging2012
22355403Regional brain differences in cortical thickness, surface area and subcortical volume in individuals with Williams syndrome.PLoS One2012
21731599Using novel control groups to dissect the amygdala's role in Williams syndrome.Dev Cogn Neurosci2011
21907520Alterations in diffusion properties of white matter in Williams syndrome.Magn Reson Imaging2011
21559500Comparative linkage meta-analysis reveals regionally-distinct, disparate genetic architectures: application to bipolar disorder and schizophrenia.PLoS One2011
20440382Auditory attraction: activation of visual cortex by music and sound in Williams syndrome.Am J Intellect Dev Disabil2010
18076107Confronting complexity in late-onset Alzheimer disease: application of two-stage analysis approach addressing heterogeneity and epistasis.Genet Epidemiol2008
20953276Association Rule Discovery Has the Ability to Model Complex Genetic Effects.IEEE Symp Comput Intell Data Min2007
16611359Dissecting trait heterogeneity: a comparison of three clustering methods applied to genotypic data.BMC Bioinformatics2006
15522460Genetics, statistics and human disease: analytical retooling for complexity.Trends Genet2004
20948983Routine Discovery of Complex Genetic Models using Genetic Algorithms.Appl Soft Comput2004
12677557PowerTrim: An automated decision support algorithm for preprocessing family-based genetic data.Am J Hum Genet2003
18428338Basic statistics.Curr Protoc Hum Genet2003
12205161Somatosensory processing in the human inferior prefrontal cortex.J Neurophysiol2002
23413413Application of Genetic Algorithms to the Discovery of Complex Models for Simulation Studies in Human Genetics.Proc Genet Evol Comput Conf2002
9356687The relationship between quality of care and financial performance in dialysis: "doing well by doing good".Adv Ren Replace Ther1997
9165654Meaningful rehabilitation of the end-stage renal disease patient.Semin Nephrol1997
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Philip L De Jager
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Lei Yu
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Robert C Green
Brigham and Women's Hospital, Broad Institute Ariadne Labs and Harvard Medical School
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Thomas J Montine
Stanford University
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Chiao-Feng Lin
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Nil??fer Ertekin-Taner
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William S Bush
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Matthew J Huentelman
The Translational Genomics Research Institute (TGen)
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Release 1.2