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Author Details

Lixin Li
Inc. 10555 Stella link
1995
24
17
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
20015465Expression of IFNalpha-inducible genes and modulation of HLA-DR and thyroid stimulating hormone receptors in Graves' disease.Mol Cell Endocrinol2010
15953541Identification and expression of a new type II transmembrane protein in human mast cells.Genomics2005
14583634Mouse chromosome 17A3.3 contains 13 genes that encode functional tryptic-like serine proteases with distinct tissue and cell expression patterns.J Biol Chem2004
16293209Mast cell and immune inhibitory receptors.Cell Mol Immunol2004
15187159Labile zinc and zinc transporter ZnT4 in mast cell granules: role in regulation of caspase activation and NF-kappaB translocation.J Immunol2004
12493770RasGRP4 regulates the expression of prostaglandin D2 in human and rat mast cell lines.J Biol Chem2003
12704212An antibody raised against in vitro-derived human mast cells identifies mature mast cells and a population of cells that are Fc epsilon RI(+), tryptase(-), and chymase(-) in a variety of human tissues.J Histochem Cytochem2003
12646205Mouse mast cells express the tryptic protease neuropsin/Prss19.Biochem Biophys Res Commun2003
12817022Mast cells in airway hyporesponsive C3H/HeJ mice express a unique isoform of the signaling protein Ras guanine nucleotide releasing protein 4 that is unresponsive to diacylglycerol and phorbol esters.J Immunol2003
11956218RasGRP4, a new mast cell-restricted Ras guanine nucleotide-releasing protein with calcium- and diacylglycerol-binding motifs. Identification of defective variants of this signaling protein in asthma, mastocytosis, and mast cell leukemia patients and demonstration of the importance of RasGRP4 in mast cell development and function.J Biol Chem2002
12194977Biochemical and functional characterization of human transmembrane tryptase (TMT)/tryptase gamma. TMT is an exocytosed mast cell protease that induces airway hyperresponsiveness in vivo via an interleukin-13/interleukin-4 receptor alpha/signal transducer and activator of transcription (STAT) 6-dependent pathway.J Biol Chem2002
12217396Cloning of rat Ras guanine nucleotide releasing protein 4, and evaluation of its expression in rat mast cells and their bone marrow progenitors.Mol Immunol2002
11602603Human tryptase epsilon (PRSS22), a new member of the chromosome 16p13.3 family of human serine proteases expressed in airway epithelial cells.J Biol Chem2001
11369641Mast cells/basophils in the peripheral blood of allergic individuals who are HIV-1 susceptible due to their surface expression of CD4 and the chemokine receptors CCR3, CCR5, and CXCR4.Blood2001
11259427Tryptase 4, a new member of the chromosome 17 family of mouse serine proteases.J Biol Chem2001
10521469Identification of a new member of the tryptase family of mouse and human mast cell proteases which possesses a novel COOH-terminal hydrophobic extension.J Biol Chem1999
10371088Mast-cell growth and differentiation.Allergy1999
10391906Human tryptases alpha and beta/II are functionally distinct due, in part, to a single amino acid difference in one of the surface loops that forms the substrate-binding cleft.J Biol Chem1999
9794446Identification of basophilic cells that express mast cell granule proteases in the peripheral blood of asthma, allergy, and drug-reactive patients.J Immunol1998
9543564Association of mast cells with fibrosis and fatty infiltration in the minor salivary glands of patients with Sjögren's syndrome.Clin Exp Rheumatol1998
9130552Conditioned media obtained from a human mastocytosis cell strain induce mast cells expressing chymase but not tryptase from human progenitors.Int Arch Allergy Immunol1997
8648132Mast cells expressing chymase but not tryptase can be derived by culturing human progenitors in conditioned medium obtained from a human mastocytosis cell strain with c-kit ligand.J Immunol1996
7613121Conditioned medium from a cell strain derived from a patient with mastocytosis induces the development of mature human mast cells in vitro from normal human bone marrow.Int Arch Allergy Immunol1995
7836459Conditioned media from a cell strain derived from a patient with mastocytosis induces preferential development of cells that possess high affinity IgE receptors and the granule protease phenotype of mature cutaneous mast cells.J Biol Chem1995
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Collaborators

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Johns Hopkins University School of Medicine
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Co-authored papers 3
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Harvard Medical School
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Brigham and Women's Hospital, Harvard Medical School
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Toranomon Hospital
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Schrodinger Inc.
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Cincinnati Children's Hospital Medical Center
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Harvard Medical School
Co-authored papers 1