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Author Details

Rainer Pepperkok
Translational Lung Research Center Heidelberg, German Center for Lung Research
1988
200
72
Emma Lundberg (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36562752CLEMSite, a software for automated phenotypic screens using light microscopy and FIB-SEM.J Cell Biol2023
37719435High-Throughput Microscopy Characterization of Rare <i>LDLR</i> Variants.JACC Basic Transl Sci2023
36807739The importance of nuclear RAGE-Mcm2 axis in diabetes or cancer-associated replication stress.Nucleic Acids Res2023
34990652Systems Approaches to Unravel Molecular Function: High-content siRNA Screen Identifies TMEM16A Traffic Regulators as Potential Drug Targets for Cystic Fibrosis.J Mol Biol2022
35829701Regulation of the COPII secretory machinery via focal adhesions and extracellular matrix signaling.J Cell Biol2022
35568682Functional profiling of LDLR variants: Important evidence for variant classification: Functional profiling of LDLR variants.J Clin Lipidol2022
36436807Repression of the iron exporter ferroportin may contribute to hepatocyte iron overload in individuals with type 2 diabetes.Mol Metab2022
33361096An integrated multiomic and quantitative label-free microscopy-based approach to study pro-fibrotic signalling in <i>ex vivo</i> human precision-cut lung slices.Eur Respir J2021
34401774A laser-mediated photo-manipulative toolbox for generation and real-time monitoring of DNA lesions.STAR Protoc2021
34741066Pairwise effects between lipid GWAS genes modulate lipid plasma levels and cellular uptake.Nat Commun2021
34230473Global distribution patterns of marine nitrogen-fixers by imaging and molecular methods.Nat Commun2021
30630895GM130 and p115 play a key role in the organisation of the early secretory pathway during skeletal muscle differentiation.J Cell Sci2019
31324722Inhibition of calpain 1 restores plasma membrane stability to pharmacologically rescued Phe508del-CFTR variant.J Biol Chem2019
30872318One step ahead: Innovation in core facilities.EMBO Rep2019
29154949A novel microscopy-based assay identifies extended synaptotagmin-1 (ESYT1) as a positive regulator of anoctamin 1 traffic.Biochim Biophys Acta Mol Cell Res2018
28977635Homeostatic nuclear RAGE-ATM interaction is essential for efficient DNA repair.Nucleic Acids Res2017
28324605Targeted Ablation Using Laser Nanosurgery.Methods Mol Biol2017
29087936Quantitative 3D-imaging for cell biology and ecology of environmental microbial eukaryotes.Elife2017
27412771Institutional core facilities: prerequisite for breakthroughs in the life sciences: Core facilities play an increasingly important role in biomedical research by providing scientists access to sophisticated technology and expertise.EMBO Rep2016
27872256The endosomal transcriptional regulator RNF11 integrates degradation and transport of EGFR.J Cell Biol2016
27926712Let there be light-at the right place.Nat Biotechnol2016
27976684Profiling DNA damage response following mitotic perturbations.Nat Commun2016
25533462A direct role for ATP1A1 in unconventional secretion of fibroblast growth factor 2.J Biol Chem2015
26459637A microtubule-independent role of p150glued in secretory cargo concentration at endoplasmic reticulum exit sites.J Cell Sci2015
26271723Novel microscopy-based screening method reveals regulators of contact-dependent intercellular transfer.Sci Rep2015
26389727Erratum: Novel microscopy-based screening method reveals regulators of contact-dependent intercellular transfer.Sci Rep2015
25647241Systematic cell-based phenotyping of missense alleles empowers rare variant association studies: a case for LDLR and myocardial infarction.PLoS Genet2015
25717003Self-organization of core Golgi material is independent of COPII-mediated endoplasmic reticulum export.J Cell Sci2015
25762484Protein traffic disorders: an effective high-throughput fluorescence microscopy pipeline for drug discovery.Sci Rep2015
25759509A Fluorescent Live Imaging Screening Assay Based on Translocation Criteria Identifies Novel Cytoplasmic Proteins Implicated in G Protein-coupled Receptor Signaling Pathways.Mol Cell Proteomics2015
25774713High-throughput fluorescence correlation spectroscopy enables analysis of proteome dynamics in living cells.Nat Biotechnol2015
24405750CNIH4 interacts with newly synthesized GPCR and controls their export from the endoplasmic reticulum.Traffic2014
24974044Adaptive fluorescence microscopy by online feedback image analysis.Methods Cell Biol2014
25189616Positive feedback between Golgi membranes, microtubules and ER exit sites directs de novo biogenesis of the Golgi.J Cell Sci2014
24659801An RNAi screen identifies KIF15 as a novel regulator of the endocytic trafficking of integrin.J Cell Sci2014
24338366Plasma membrane translocation of REDD1 governed by GPCRs contributes to mTORC1 activation.J Cell Sci2014
24425787PIPâ¿¿ induces the recycling of receptor tyrosine kinases.Sci Signal2014
23435261Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells.Nat Methods2013
24295315Golgi depletion from living cells with laser nanosurgery.Methods Cell Biol2013
24056303PtdIns(3)P-bound UVRAG coordinates Golgi-ER retrograde and Atg9 transport by differential interactions with the ER tether and the beclin 1 complex.Nat Cell Biol2013
24244038Imaging ER-to-Golgi transport: towards a systems view.J Cell Sci2013
24034256High-content siRNA screen reveals global ENaC regulators and potential cystic fibrosis therapy targets.Cell2013
23632384Characterization of drug-induced transcriptional modules: towards drug repositioning and functional understanding.Mol Syst Biol2013
23468663RNAi-based functional profiling of loci from blood lipid genome-wide association studies identifies genes with cholesterol-regulatory function.PLoS Genet2013
23435994Cell-to-cell communication: current views and future perspectives.Cell Tissue Res2013
22075984Nucleoporin NUP153 guards genome integrity by promoting nuclear import of 53BP1.Cell Death Differ2012
22973456Chemical chaperones improve protein secretion and rescue mutant factor VIII in mice with hemophilia A.PLoS One2012
23029645At the cutting edge: applications and perspectives of laser nanosurgery in cell biology.Biol Chem2012
22660414Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway.Nat Cell Biol2012
22230960Molecular recognition of a single sphingolipid species by a protein's transmembrane domain.Nature2012
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Collaborators

Jeremy C Simpson
UCD Conway Institute of Biomolecular and Biomedical Science
Co-authored papers 33
Stefan Wiemann
Co-authored papers 17
Jan Ellenberg
Institute of Child Health and Human Development
Co-authored papers 16
Beate Neumann
Center for Molecular Materials, Universitat Bielefeld, Universitatsstrasse 25
Co-authored papers 15
Christian Tischer
Center for Bioimage Analysis
Co-authored papers 8
Stefan Terjung
Co-authored papers 7
Vibor Laketa
Heidelberg University Hospital
Co-authored papers 6
Jutta Bulkescher
Novo Nordisk Foundation Center for Protein Research, University of Copenhagen
Co-authored papers 6
Jean-Karim H??rich??
University of California san francisco
Co-authored papers 6
Alexander Mehrle
Co-authored papers 6
Wolfgang Huber
Technische Universitat Munchen
Co-authored papers 6
Thomas Walter
PSL University
Co-authored papers 5
Peer Bork
University of Wurzburg
Co-authored papers 4
Angus I Lamond
University of Dundee
Co-authored papers 4
Roland Eils
Berlin Institute of Health (BIH) and Charite
Co-authored papers 4
Mathias Uhl??n
KTH Royal Institute of Technology
Co-authored papers 3
Claudia Lukas
Novo Nordisk Foundation Center for Protein Research, University of Copenhagen
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Emma Lundberg (CM4AI)
Stanford University
Co-authored papers 3
Arne Seitz
Co-authored papers 3
Daniel W Gerlich
Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA)
Co-authored papers 2
Charlotte Stadler
KTH Royal Institute of Technology and Science for Life Laboratories
Co-authored papers 2
Heiko Rosenfelder
Co-authored papers 2
Murat Iskar
Friedrich Miescher Institute for Biomedical Research
Co-authored papers 2
Ina Poser
Max Planck Institute of Molecular Cell Biology and Genetics
Co-authored papers 2
Holger S??ltmann
German Cancer Research Center (DKFZ)
Co-authored papers 2
Oliver Hofmann
University of Melbourne
Co-authored papers 2
Vasanth R Singan
US Department of Energy Joint Genome Institute, Lawrence Berkeley National Laboratory
Co-authored papers 2
Reinhard Schneider
Co-authored papers 2
Florian Hahne
1 Preclinical Safety, Novartis Institutes for Biomedical Research
Co-authored papers 2
Winston Hide
Harvard Medical School
Co-authored papers 2
Release 1.2