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Author Details

Kara Johnson
Knight Cancer Institute, Oregon Health & Science University
1991
17
14
PMIDPaper TitleJournal TitlePublished Year
37199721Patient-Specific Targeting of the T-Cell Receptor Variable Region as a Therapeutic Strategy in Clonal T-Cell Diseases.Clin Cancer Res2023
35868306Integrative analysis of drug response and clinical outcome in acute myeloid leukemia.Cancer Cell2022
30333627Functional genomic landscape of acute myeloid leukaemia.Nature2018
25895498YM155 potently kills acute lymphoblastic leukemia cells through activation of the DNA damage pathway.J Hematol Oncol2015
26202934β-Catenin is required for intrinsic but not extrinsic BCR-ABL1 kinase-independent resistance to tyrosine kinase inhibitors in chronic myeloid leukemia.Leukemia2015
23576564Threshold levels of ABL tyrosine kinase inhibitors retained in chronic myeloid leukemia cells determine their commitment to apoptosis.Cancer Res2013
19823681A BCR-ABL mutant lacking direct binding sites for the GRB2, CBL and CRKL adapter proteins fails to induce leukemia in mice.PLoS One2009
16880519Kinase domain mutants of Bcr-Abl exhibit altered transformation potency, kinase activity, and substrate utilization, irrespective of sensitivity to imatinib.Mol Cell Biol2006
16772610Comparison of imatinib mesylate, dasatinib (BMS-354825), and nilotinib (AMN107) in an N-ethyl-N-nitrosourea (ENU)-based mutagenesis screen: high efficacy of drug combinations.Blood2006
15665113Synergistic interactions between imatinib mesylate and the novel phosphoinositide-dependent kinase-1 inhibitor OSU-03012 in overcoming imatinib mesylate resistance.Blood2005
12933582In vitro efficacy of combined treatment depends on the underlying mechanism of resistance in imatinib-resistant Bcr-Abl-positive cell lines.Blood2004
14725908Coexistence of phosphotyrosine-dependent and -independent interactions between Cbl and Bcr-Abl.Exp Hematol2004
12135670In vitro studies of the combination of imatinib mesylate (Gleevec) and arsenic trioxide (Trisenox) in chronic myelogenous leukemia.Exp Hematol2002
11320143Induction of mutant lymphocytes in cyclophosphamide- and chlorambucil-treated patients.Mutagenesis2001
9822717Interactions of p62(dok) with p210(bcr-abl) and Bcr-Abl-associated proteins.J Biol Chem1998
8349586Isolation and analysis of the gene and cDNA for a human Mu class glutathione S-transferase, GSTM4.J Biol Chem1993
2050131Dose-dependent cytotoxic and mutagenic effects of antineoplastic alkylating agents on human lymphoblastoid cells.Environ Mol Mutagen1991
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Collaborators

Oregon Health & Science University
Co-authored papers 13
University of Utah Huntsman Cancer Institute
Co-authored papers 9
Huntsman Cancer Institute, University of Utah
Co-authored papers 5
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Co-authored papers 5
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Co-authored papers 4
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Co-authored papers 4
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Co-authored papers 4
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Co-authored papers 3
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Co-authored papers 3
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Co-authored papers 3
Oregon Health and Science University
Co-authored papers 2
University of Colorado Division of Hematology
Co-authored papers 2
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 2
Astex Pharmaceuticals
Co-authored papers 2
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 2
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 2
Oregon Health & Science University, Knight Cancer Institute
Co-authored papers 2
Oregon Health & Science University
Co-authored papers 2
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Co-authored papers 2
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Co-authored papers 2
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 2
Emory School of Medicine
Co-authored papers 2
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 2
Oregon Health & Science University
Co-authored papers 2
Knight Cancer Institute, Oregon Health Sciences University
Co-authored papers 2
National Cancer Institute, National Institutes of Health
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University of Miami, Sylvester Comprehensive Cancer Center
Co-authored papers 2
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 2
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 2
OHSU Cancer Institute
Co-authored papers 2