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Author Details
Full Name
Kara Johnson
Affiliation
Knight Cancer Institute, Oregon Health & Science University
ORCID
Career Start Year
1991
Papers
17
H Index
14
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
37199721
Patient-Specific Targeting of the T-Cell Receptor Variable Region as a Therapeutic Strategy in Clonal T-Cell Diseases.
Clin Cancer Res
2023
35868306
Integrative analysis of drug response and clinical outcome in acute myeloid leukemia.
Cancer Cell
2022
30333627
Functional genomic landscape of acute myeloid leukaemia.
Nature
2018
25895498
YM155 potently kills acute lymphoblastic leukemia cells through activation of the DNA damage pathway.
J Hematol Oncol
2015
26202934
β-Catenin is required for intrinsic but not extrinsic BCR-ABL1 kinase-independent resistance to tyrosine kinase inhibitors in chronic myeloid leukemia.
Leukemia
2015
23576564
Threshold levels of ABL tyrosine kinase inhibitors retained in chronic myeloid leukemia cells determine their commitment to apoptosis.
Cancer Res
2013
19823681
A BCR-ABL mutant lacking direct binding sites for the GRB2, CBL and CRKL adapter proteins fails to induce leukemia in mice.
PLoS One
2009
16880519
Kinase domain mutants of Bcr-Abl exhibit altered transformation potency, kinase activity, and substrate utilization, irrespective of sensitivity to imatinib.
Mol Cell Biol
2006
16772610
Comparison of imatinib mesylate, dasatinib (BMS-354825), and nilotinib (AMN107) in an N-ethyl-N-nitrosourea (ENU)-based mutagenesis screen: high efficacy of drug combinations.
Blood
2006
15665113
Synergistic interactions between imatinib mesylate and the novel phosphoinositide-dependent kinase-1 inhibitor OSU-03012 in overcoming imatinib mesylate resistance.
Blood
2005
12933582
In vitro efficacy of combined treatment depends on the underlying mechanism of resistance in imatinib-resistant Bcr-Abl-positive cell lines.
Blood
2004
14725908
Coexistence of phosphotyrosine-dependent and -independent interactions between Cbl and Bcr-Abl.
Exp Hematol
2004
12135670
In vitro studies of the combination of imatinib mesylate (Gleevec) and arsenic trioxide (Trisenox) in chronic myelogenous leukemia.
Exp Hematol
2002
11320143
Induction of mutant lymphocytes in cyclophosphamide- and chlorambucil-treated patients.
Mutagenesis
2001
9822717
Interactions of p62(dok) with p210(bcr-abl) and Bcr-Abl-associated proteins.
J Biol Chem
1998
8349586
Isolation and analysis of the gene and cDNA for a human Mu class glutathione S-transferase, GSTM4.
J Biol Chem
1993
2050131
Dose-dependent cytotoxic and mutagenic effects of antineoplastic alkylating agents on human lymphoblastoid cells.
Environ Mol Mutagen
1991
1 - 17 of 17
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Daniel A Pollyea
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Cristina E Tognon
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Haijiao Zhang
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