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Author Details

Liang Tong
Columbia University
1988
299
76
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36822327An examination of the metal ion content in the active sites of human endonucleases CPSF73 and INTS11.J Biol Chem2023
37562960In vitro methylation of the U7 snRNP subunits Lsm11 and SmE by the PRMT5/MEP50/pICln methylosome.RNA2023
37215023<i>In vitro</i> methylation of the U7 snRNP subunits Lsm11 and SmE by the PRMT5/MEP50/pICln methylosome.bioRxiv2023
36977380The heterochronic LIN-14 protein is a BEN domain transcription factor.Curr Biol2023
36995121A partially open conformation of an androgen receptor ligand-binding domain with drug-resistance mutations.Acta Crystallogr F Struct Biol Commun2023
36787367Cytoskeletal association of ATP citrate lyase controls the mechanodynamics of macropinocytosis.Proc Natl Acad Sci U S A2023
36634676Integrator is a global promoter-proximal termination complex.Mol Cell2023
36385225Author Correction: CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.Nat Commun2022
36459648DHX15 is involved in SUGP1-mediated RNA missplicing by mutant SF3B1 in cancer.Proc Natl Acad Sci U S A2022
36180473Inositol hexakisphosphate is required for Integrator function.Nat Commun2022
35904778Identification of a novel deFADding activity in human, yeast and bacterial 5' to 3' exoribonucleases.Nucleic Acids Res2022
36130077Molecular basis for the recognition of the AUUAAA polyadenylation signal by mPSF.RNA2022
36229431INTS13 variants causing a recessive developmental ciliopathy disrupt assembly of the Integrator complex.Nat Commun2022
35984649Pharmacologic Inhibition of NT5C2 Reverses Genetic and Nongenetic Drivers of 6-MP Resistance in Acute Lymphoblastic Leukemia.Cancer Discov2022
36261450CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.Nat Commun2022
33349676How to diSARM the executioner of axon degeneration.Nat Struct Mol Biol2021
33649224Structural basis for a bacterial Pip system plant effector recognition protein.Proc Natl Acad Sci U S A2021
34351387U7 deciphered: the mechanism that forms the unusual 3' end of metazoan replication-dependent histone mRNAs.Biochem Soc Trans2021
34183127Reconstitution and biochemical assays of an active human histone pre-mRNA 3'-end processing machinery.Methods Enzymol2021
34010645The histone H3K9M mutation synergizes with H3K14 ubiquitylation to selectively sequester histone H3K9 methyltransferase Clr4 at heterochromatin.Cell Rep2021
34309402A Rationally Designed c-di-AMP Förster Resonance Energy Transfer Biosensor To Monitor Nucleotide Dynamics.J Bacteriol2021
34230059A real-time fluorescence assay for CPSF73, the nuclease for pre-mRNA 3'-end processing.RNA2021
34165569Correction to 'A novel 5'-hydroxyl dinucleotide hydrolase activity for the DXO/Rai1 family of enzymes'.Nucleic Acids Res2021
33431973Crystal structure of a thermophilic fungal cyanase and its implications on the catalytic mechanism for bioremediation.Sci Rep2021
33252730Structure and Function of the Separase-Securin Complex.Subcell Biochem2021
33397729Corrigendum: Molecular mechanism for the interaction between human CPSF30 and hFip1.Genes Dev2021
32374864DXO/Rai1 enzymes remove 5'-end FAD and dephospho-CoA caps on RNAs.Nucleic Acids Res2020
31810758Structural Insights into the Human Pre-mRNA 3'-End Processing Machinery.Mol Cell2020
31777937A novel 5'-hydroxyl dinucleotide hydrolase activity for the DXO/Rai1 family of enzymes.Nucleic Acids Res2020
31794207High-Throughput PIXE as an Essential Quantitative Assay for Accurate Metalloprotein Structural Analysis: Development and Application.J Am Chem Soc2020
33122294Molecular mechanism for the interaction between human CPSF30 and hFip1.Genes Dev2020
32890683Cryo-EM as a powerful tool for drug discovery.Bioorg Med Chem Lett2020
32843560(p)ppGpp and c-di-AMP Homeostasis Is Controlled by CbpB in Listeria monocytogenes.mBio2020
32554553Studies with recombinant U7 snRNP demonstrate that CPSF73 is both an endonuclease and a 5'-3' exonuclease.RNA2020
32522085Recent molecular insights into canonical pre-mRNA 3'-end processing.Transcription2020
32432673Mammalian Nudix proteins cleave nucleotide metabolite caps on RNAs.Nucleic Acids Res2020
31104813Identification of Three Sequence Motifs in the Transcription Termination Factor Sen1 that Mediate Direct Interactions with Nrd1.Structure2019
31462423Biophysical characterizations of the recognition of the AAUAAA polyadenylation signal.RNA2019
31101919Structural and mechanistic basis of mammalian Nudt12 RNA deNADding.Nat Chem Biol2019
30949699Arabidopsis DXO1 links RNA turnover and chloroplast function independently of its enzymatic activity.Nucleic Acids Res2019
30949693Arabidopsis DXO1 links RNA turnover and chloroplast function independently of its enzymatic activity.Nucleic Acids Res2019
30944472An allosteric mechanism for potent inhibition of human ATP-citrate lyase.Nature2019
29251719Expression system for structural and functional studies of human glycosylation enzymes.Nat Chem Biol2018
30211541How Does Polymerization Regulate Human Acetyl-CoA Carboxylase 1?Biochemistry2018
29990496Structure and Mechanisms of NT5C2 Mutations Driving Thiopurine Resistance in Relapsed Lymphoblastic Leukemia.Cancer Cell2018
30180947Molecular mechanism for the inhibition of DXO by adenosine 3',5'-bisphosphate.Biochem Biophys Res Commun2018
29873848Insulin Hexamer-Caged Gadolinium Ion as MRI Contrast-o-phore.Chemistry2018
30387777High-resolution structures of inhibitor complexes of human indoleamine 2,3-dioxygenase 1 in a new crystal form.Acta Crystallogr F Struct Biol Commun2018
29471365Integrator subunit 4 is a 'Symplekin-like' scaffold that associates with INTS9/11 to form the Integrator cleavage module.Nucleic Acids Res2018
29452922Structural biology of the separase-securin complex with crucial roles in chromosome segregation.Curr Opin Struct Biol2018
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Collaborators

Gaetano T Montelione
Rensselaer Polytechnic Institute
Co-authored papers 36
Rong Xiao
School of Public Health, Capital Medical University
Co-authored papers 31
Thomas B Acton
Center for Advanced Biotechnology and Medicine, The State University of New Jersey
Co-authored papers 24
Michael G Rossmann
Purdue University
Co-authored papers 11
Sung-Hou Kim
University of California berkeley
Co-authored papers 11
Sergey M Vorobiev
Columbia University
Co-authored papers 11
Yang Shen
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Co-authored papers 9
John F Hunt
Columbia University
Co-authored papers 9
Michael A Kennedy
Miami University
Co-authored papers 7
William F Marzluff
University of North Carolina at Chapel Hill
Co-authored papers 5
Yun Bai
Carnegie Institution for Science
Co-authored papers 5
Yuanpeng J Huang
Center for Advanced Biotechnology and Medicine, The State University of New Jersey
Co-authored papers 5
Cheryl H Arrowsmith
University of Toronto
Co-authored papers 5
Mikel Valle
Center for Cooperative Research in Biosciences (CIC bioGUNE)
Co-authored papers 5
Haleema Janjua
Center for Advanced Biotechnology and Medicine, The State University of New Jersey
Co-authored papers 5
David Baker
University of Washington
Co-authored papers 4
Li Zhao
The Ohio State University
Co-authored papers 4
Aled M Edwards
University of Toronto
Co-authored papers 4
Alexei Savchenko
University of Toronto
Co-authored papers 3
John R Cort
Pacific Northwest National Laboratory
Co-authored papers 3
Zhen-Hong Zhou
Co-authored papers 3
Li-Chung Ma
Robert Wood Johnson Medical School, The State University of New Jersey
Co-authored papers 3
Hongyu Deng
Cancer Research Institute, Central South University
Co-authored papers 2
Daniel A Portnoy
University of California berkeley
Co-authored papers 2
Dongyan Wang
Guizhou Medical University
Co-authored papers 2
Opher Gileadi
Structural Genomics Consortium Karolinska Institute Stockholm Sweden.
Co-authored papers 2
Kellie Cunningham
Co-authored papers 2
Ritu Shastry
Co-authored papers 2
Sagar D Khare
The State University of New Jersey
Co-authored papers 2
Ming Sun
Columbia University
Co-authored papers 2
Release 1.2