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Author Details

Christopher Szeto
La Trobe Institute for Molecular Science, La Trobe University
2005
48
23
PMIDPaper TitleJournal TitlePublished Year
37749325Newborn and child-like molecular signatures in older adults stem from TCR shifts across human lifespan.Nat Immunol2023
35255101HLA-A*11:01-restricted CD8+ T cell immunity against influenza A and influenza B viruses in Indigenous and non-Indigenous people.PLoS Pathog2022
35999236Covalent TCR-peptide-MHC interactions induce T cell activation and redirect T cell fate in the thymus.Nat Commun2022
36275878Homologous peptides derived from influenza A, B and C viruses induce variable CD8<sup>+</sup> T cell responses with cross-reactive potential.Clin Transl Immunology2022
36302758Ablation of CD8<sup>+</sup> T cell recognition of an immunodominant epitope in SARS-CoV-2 Omicron variants BA.1, BA.2 and BA.3.Nat Commun2022
33945786CD8<sup>+</sup> T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope cross-react with selective seasonal coronaviruses.Immunity2021
33521593The presentation of SARS-CoV-2 peptides by the common HLA-A<sup>â¿¿</sup>02:01 molecule.iScience2021
34581761The pockets guide to HLA class I molecules.Biochem Soc Trans2021
34685626Molecular Basis of a Dominant SARS-CoV-2 Spike-Derived Epitope Presented by HLA-A*02:01 Recognised by a Public TCR.Cells2021
34124695Protein purification and crystallization of HLA-Aâ¿¿02:01 in complex with SARS-CoV-2 peptides.STAR Protoc2021
34006841CD8<sup>+</sup> T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph.Nat Commun2021
34083463Canonical T cell receptor docking on peptide-MHC is essential for T cell signaling.Science2021
32493840Transcriptomic silencing as a potential mechanism of treatment resistance.JCI Insight2020
33374673TCR Recognition of Peptide-MHC-I: Rule Makers and Breakers.Int J Mol Sci2020
33077815Large scale, robust, and accurate whole transcriptome profiling from clinical formalin-fixed paraffin-embedded samples.Sci Rep2020
32913030Complete response to avelumab and IL-15 superagonist N-803 with Abraxane in Merkel cell carcinoma: a case study.J Immunother Cancer2020
32992915Impact of HLA-DR Antigen Binding Cleft Rigidity on T Cell Recognition.Int J Mol Sci2020
32113130The unconventional role of HLA-E: The road less traveled.Mol Immunol2020
30579113Refining the selection of patients with metastatic colorectal cancer for treatment with temozolomide using proteomic analysis of O6-methylguanine-DNA-methyltransferase.Eur J Cancer2019
31703605Treatment with checkpoint inhibitors in a metastatic colorectal cancer patient with molecular and immunohistochemical heterogeneity in MSI/dMMR status.J Immunother Cancer2019
31651374Impact of marginalization on tobacco use in individuals diagnosed with head and neck Cancer.J Otolaryngol Head Neck Surg2019
31563852Deep Learning Implicitly Handles Tissue Specific Phenomena to Predict Tumor DNA Accessibility and Immune Activity.iScience2019
30982412Cardiomyocyte PKA Ablation Enhances Basal Contractility While Eliminates Cardiac β-Adrenergic Response Without Adverse Effects on the Heart.Circ Res2019
29274077Increasing T-type calcium channel activity by β-adrenergic stimulation contributes to β-adrenergic regulation of heart rates.J Physiol2018
29808010Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition.Nat Med2018
30093730Author Correction: Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition.Nat Med2018
30713787The multi-functionality of N-809, a novel fusion protein encompassing anti-PD-L1 and the IL-15 superagonist fusion complex.Oncoimmunology2018
28511858Reduced Myocardial Reserve in Young X-Linked Muscular Dystrophy Mice Diagnosed by Two-Dimensional Strain Analysis Combined with Stress Echocardiography.J Am Soc Echocardiogr2017
26923050Bovine leukemia virus infection in cattle of China: Association with reduced milk production and increased somatic cell score.J Dairy Sci2016
26611208Persistent increases in Ca(2+) influx through Cav1.2 shortens action potential and causes Ca(2+) overload-induced afterdepolarizations and arrhythmias.Basic Res Cardiol2016
26097482Animal Models of Interferon Signature Positive Lupus.Front Immunol2015
24460932Contact endoscopy as a novel technique in the detection and diagnosis of oral cavity and oropharyngeal mucosal lesions in the head and neck.J Laryngol Otol2014
23104882Cardiotoxic and cardioprotective features of chronic β-adrenergic signaling.Circ Res2013
23663280Development of a transoral robotic surgery program in Canada.J Otolaryngol Head Neck Surg2013
22076949Detection of circulating tumor cells in advanced head and neck cancer using the CellSearch system.Head Neck2012
23304554A Pilot Study Comparing HPV-Positive and HPV-Negative Head and Neck Squamous Cell Carcinomas by Whole Exome Sequencing.ISRN Oncol2012
22762698Postlaryngectomy pharyngocutaneous fistula: determining the risk of preoperative tracheostomy and primary tracheoesophageal puncture.J Otolaryngol Head Neck Surg2012
22808078β-Adrenergic stimulation increases Cav3.1 activity in cardiac myocytes through protein kinase A.PLoS One2012
22344691Contribution of the first K-homology domain of poly(C)-binding protein 1 to its affinity and specificity for C-rich oligonucleotides.Nucleic Acids Res2012
21209710Contact endoscopy as a novel technique in the detection and diagnosis of mucosal lesions in the head and neck: a brief review.J Oncol2011
21593669The buccinator flap: a review of current clinical applications.Curr Opin Otolaryngol Head Neck Surg2011
21111744Calcium influx through Cav1.2 is a proximal signal for pathological cardiomyocyte hypertrophy.J Mol Cell Cardiol2011
21059681The UCSC Cancer Genomics Browser: update 2011.Nucleic Acids Res2011
20647124A simple method to predict pretracheal tissue thickness to prevent accidental decannulation in the obese.Otolaryngol Head Neck Surg2010
20543081Enhanced basal contractility but reduced excitation-contraction coupling efficiency and beta-adrenergic reserve of hearts with increased Cav1.2 activity.Am J Physiol Heart Circ Physiol2010
20529912Inference of patient-specific pathway activities from multi-dimensional cancer genomics data using PARADIGM.Bioinformatics2010
19333237The UCSC Cancer Genomics Browser.Nat Methods2009
15927272Pai syndrome (median cleft palate, cutaneous nasal polyp, and midline lipoma of the corpus callosum): a case report and literature review.Int J Pediatr Otorhinolaryngol2005
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Collaborators

Kevin Fung
Schulich School of Medicine & Dentistry, Western University, Victoria Hospital
Co-authored papers 8
Jason H Franklin
Queen's University
Co-authored papers 7
John Yoo
Schulich School of Medicine & Dentistry, Western University
Co-authored papers 7
Anthony C Nichols
University of Western Ontario
Co-authored papers 7
John Z Sanborn
Co-authored papers 5
Steven R Houser
Cardiovascular Research Center, Lewis Katz School of Medicine, Temple University
Co-authored papers 4
Samuel Dowthwaite
Gold Coast University Hospital
Co-authored papers 4
David A Palma
University of Western Ontario
Co-authored papers 3
John Basmaji
Schulich School of Medicine and Dentistry, Western University
Co-authored papers 3
Sandeep Dhaliwal
University of California at Davis School of Medicine
Co-authored papers 3
John W Barrett
University of Western Ontario
Co-authored papers 3
David Haussler
Genomics Institute, University of California Santa Cruz
Co-authored papers 3
Jingchun Zhu
University of California at Santa Cruz
Co-authored papers 3
Bret Wehrli
Schulich School of Medicine & Dentistry, Western University
Co-authored papers 3
Donna Karolchik
Co-authored papers 2
James Koropatnick
Western University, Lawson Health Research Institute
Co-authored papers 2
Steven E Schumacher
Co-authored papers 2
John Alan Diehl
Case Western Reserve University School of Medicine
Co-authored papers 2
Joe S Mymryk
University of Western Ontario
Co-authored papers 2
Rameen Beroukhim
Co-authored papers 2
Adam J Bass
Co-authored papers 2
Rajiv Khanna
Co-authored papers 2
Joshua M Stuart
University of California at Santa Cruz
Co-authored papers 2
Austin Dulak
Co-authored papers 2
Philipp Mertins
Co-authored papers 2
Anthony W Purcell
Monash Biomedicine Discovery Institute, Monash University
Co-authored papers 2
Yulia Newton
University of California, Santa Cruz Genomics Institute
Co-authored papers 2
William James Kent
Co-authored papers 2
Steven A Carr
Broad Institute of MIT and Harvard
Co-authored papers 2
Robert M Kuhn
Genomics Institute, University of California Santa Cruz
Co-authored papers 2
Release 1.2