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Author Details

Ignacio Mena
Icahn School of Medicine at Mount Sinai
1994
65
25
Kirsten Obernier (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
38064025Rescue of Recombinant Newcastle Disease Virus Expressing Heterologous Genes.Methods Mol Biol2024
37425792Breakthrough infections by SARS-CoV-2 variants boost cross-reactive hybrid immune responses in mRNA-vaccinated Golden Syrian Hamsters.bioRxiv2023
37738983Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis.Cell Host Microbe2023
37738970SARS-CoV-2 variants evolve convergent strategies to remodel the host response.Cell2023
37693425Generation of antigen-specific memory CD4 T cells by heterologous immunization enhances the magnitude of the germinal center response upon influenza infection.bioRxiv2023
35150638Mutations in SARS-CoV-2 variants of concern link to increased spike cleavage and virus transmission.Cell Host Microbe2022
35658571Trivalent NDV-HXP-S Vaccine Protects against Phylogenetically Distant SARS-CoV-2 Variants of Concern in Mice.Microbiol Spectr2022
36581658An intranasal recombinant NDV-BRSV F<sub>opt</sub> vaccine is safe and reduces lesion severity in a colostrum-deprived calf model of RSV infection.Sci Rep2022
36561187Surface-modified measles vaccines encoding oligomeric, fusion-stabilized SARS-CoV-2 spike glycoproteins bypass measles seropositivity, boosting neutralizing antibody responses to omicron and historical variants.bioRxiv2022
36561180Visualization of early RNA replication kinetics of SARS-CoV-2 by using single molecule RNA-FISH.bioRxiv2022
36044897Discovery and intranasal administration of a SARS-CoV-2 broadly acting neutralizing antibody with activity against multiple Omicron subvariants.Med2022
35937459Avian Paramyxovirus 4 Antitumor Activity Leads to Complete Remissions and Long-term Protective Memory in Preclinical Melanoma and Colon Carcinoma Models.Cancer Res Commun2022
35284808Safety and immunogenicity of an inactivated recombinant Newcastle disease virus vaccine expressing SARS-CoV-2 spike: Interim results of a randomised, placebo-controlled, phase 1 trial.EClinicalMedicine2022
33948589Prophylactic protection against respiratory viruses conferred by a prototype live attenuated influenza virus vaccine.bioRxiv2021
33501468The N501Y mutation in SARS-CoV-2 spike leads to morbidity in obese and aged mice and is neutralized by convalescent and post-vaccination human sera.medRxiv2021
34707161A Newcastle disease virus expressing a stabilized spike protein of SARS-CoV-2 induces protective immune responses.Nat Commun2021
34401874Prophylactic Protection Against Respiratory Viruses Conferred by a Prototype Live Attenuated Influenza Virus Vaccine.Res Sq2021
34580673Safety and Immunogenicity of an Inactivated Recombinant Newcastle Disease Virus Vaccine Expressing SARS-CoV-2 Spike: Interim Results of a Randomised, Placebo-Controlled, Phase 1/2 Trial.medRxiv2021
34773048Interferon mediated prophylactic protection against respiratory viruses conferred by a prototype live attenuated influenza virus vaccine lacking non-structural protein 1.Sci Rep2021
32546784Author Correction: Microbiome disturbance and resilience dynamics of the upper respiratory tract during influenza A virus infection.Nat Commun2020
31776276Viral Determinants in H5N1 Influenza A Virus Enable Productive Infection of HeLa Cells.J Virol2020
33097660SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling.Proc Natl Acad Sci U S A2020
32439901Microbiome disturbance and resilience dynamics of the upper respiratory tract during influenza A virus infection.Nat Commun2020
32357948Precise location of linear epitopes on the capsid surface of feline calicivirus recognized by neutralizing and non-neutralizing monoclonal antibodies.Vet Res2020
30730827Human-Origin Influenza A(H3N2) Reassortant Viruses in Swine, Southeast Mexico.Emerg Infect Dis2019
31851929Viral Fitness Landscapes in Diverse Host Species Reveal Multiple Evolutionary Lines for the NS1 Gene of Influenza A Viruses.Cell Rep2019
31597767Differential Modulation of Innate Immune Responses in Human Primary Cells by Influenza A Viruses Carrying Human or Avian Nonstructural Protein 1.J Virol2019
29321309Specific Mutations in the PB2 Protein of Influenza A Virus Compensate for the Lack of Efficient Interferon Antagonism of the NS1 Protein of Bat Influenza A-Like Viruses.J Virol2018
30177761Influenza virus infection causes global RNAPII termination defects.Nat Struct Mol Biol2018
29779923A viral-vectored RSV vaccine induces long-lived humoral immunity in cotton rats.Vaccine2018
29799537Erratum: Author Correction: Newcastle disease virus-based H5 influenza vaccine protects chickens from lethal challenge with a highly pathogenic H5N2 avian influenza virus.NPJ Vaccines2018
29395518Influenza B virus reverse genetic backbones with improved growth properties in the EB66® cell line as basis for vaccine seed virus generation.Vaccine2018
28679950High-dimensional CyTOF analysis of dengue virus-infected human DCs reveals distinct viral signatures.JCI Insight2017
28282445Endothelial cell tropism is a determinant of H5N1 pathogenesis in mammalian species.PLoS Pathog2017
28278235A novel Zika virus mouse model reveals strain specific differences in virus pathogenesis and host inflammatory immune responses.PLoS Pathog2017
28953980Influenza virus differentially activates mTORC1 and mTORC2 signaling to maximize late stage replication.PLoS Pathog2017
29263888Newcastle disease virus-based H5 influenza vaccine protects chickens from lethal challenge with a highly pathogenic H5N2 avian influenza virus.NPJ Vaccines2017
28592526Novel Cross-Reactive Monoclonal Antibodies against Ebolavirus Glycoproteins Show Protection in a Murine Challenge Model.J Virol2017
27102817Recombinant Newcastle disease virus expressing H9 HA protects chickens against heterologous avian influenza H9N2 virus challenge.Vaccine2016
27350259Origins of the 2009 H1N1 influenza pandemic in swine in Mexico.Elife2016
27549017Rabbit hemorrhagic disease virus capsid, a versatile platform for foreign B-cell epitope display inducing protective humoral immune responses.Sci Rep2016
25926639Newcastle Disease Virus-Vectored H7 and H5 Live Vaccines Protect Chickens from Challenge with H7N9 or H5N1 Avian Influenza Viruses.J Virol2015
24726997The origin of the PB1 segment of swine influenza A virus subtype H1N2 determines viral pathogenicity in mice.Virus Res2014
25055345An infectious bat-derived chimeric influenza virus harbouring the entry machinery of an influenza A virus.Nat Commun2014
23536663Substitutions T200A and E227A in the hemagglutinin of pandemic 2009 influenza A virus increase lethality but decrease transmission.J Virol2013
26038474Influenza A(H1N1)pdm09 virus infection in marine mammals in California.Emerg Microbes Infect2013
23690933Pandemic H1N1 influenza isolated from free-ranging Northern Elephant Seals in 2010 off the central California coast.PLoS One2013
23477832Novel vaccine strategies against emerging viruses.Curr Opin Virol2013
21989404RNA self-cleavage activated by ultraviolet light-induced oxidation.Nucleic Acids Res2012
22491457Epitope insertion at the N-terminal molecular switch of the rabbit hemorrhagic disease virus T = 3 capsid protein leads to larger T = 4 capsids.J Virol2012
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Collaborators

Adolfo Garc??a-Sastre
Icahn School of Medicine at Mount Sinai
Co-authored papers 41
Raveen Rathnasinghe
Icahn School of Medicine at Mount Sinai New York
Co-authored papers 11
Michael Schotsaert
Icahn School of Medicine at Mount Sinai
Co-authored papers 10
Randy A Albrecht
Icahn School of Medicine at Mount Sinai
Co-authored papers 9
Peter Palese
Icahn School of Medicine at Mount Sinai
Co-authored papers 7
Juergen A Richt
College of Veterinary Medicine, Kansas State University
Co-authored papers 6
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 5
Lisa Miorin
Icahn School of Medicine at Mount Sinai
Co-authored papers 5
Harm van Bakel
Icahn School of Medicine at Mount Sinai
Co-authored papers 5
Sadaf Aslam
University of South Florida
Co-authored papers 5
Viviana Simon
Icahn School of Medicine at Mount Sinai
Co-authored papers 4
Juan Ayllon
Icahn School of Medicine at Mount Sinai
Co-authored papers 4
Kris M White
Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG)
Co-authored papers 4
Carles Mart??nez-Romero
Icahn School of Medicine at Mount Sinai
Co-authored papers 4
Teresa Aydillo
Icahn School of Medicine at Mount Sinai
Co-authored papers 3
Lorena Zuliani-Alvarez
J. David Gladstone Institutes
Co-authored papers 3
Mehdi Bouhaddou
J. David Gladstone Institutes
Co-authored papers 3
Ana S Gonzalez-Reiche
Icahn School of Medicine at Mount Sinai
Co-authored papers 3
Beatriz M A Fontoura
University of Texas Southwestern Medical Center
Co-authored papers 3
Emilia Mia Sordillo
Icahn School of Medicine at Mount Sinai
Co-authored papers 3
Ana Fernandez-Sesma
Icahn School of Medicine at Mount Sinai
Co-authored papers 3
Soner Yildiz
University of Geneva
Co-authored papers 3
Giorgi Metreveli
Icahn School of Medicine at Mount Sinai
Co-authored papers 2
Chester McDowell
College of Veterinary Medicine, Kansas State University
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Martin Schwemmle
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Co-authored papers 2
Thomas P Zwaka
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Vinod R M T Balasubramaniam
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Release 1.2