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Author Details

Bo Li
The University of North Carolina at Chapel Hill
2006
33
20
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37348664Purification and characterization of tomato arginine decarboxylase and its inhibition by the bacterial small molecule phevamine A.Protein Expr Purif2023
37561838Chemoproteomics Reveals Disruption of Metal Homeostasis and Metalloproteins by the Antibiotic Holomycin.ACS Chem Biol2023
34342433Inhibition of Isoleucyl-tRNA Synthetase by the Hybrid Antibiotic Thiomarinol.J Am Chem Soc2021
34793213Biosynthesis of fluopsin C, a copper-containing antibiotic from <i>Pseudomonas aeruginosa</i>.Science2021
32662921In Vitro Reconstitution Reveals a Central Role for the N-Oxygenase PvfB in (Dihydro)pyrazine-N-oxide and Valdiazen Biosynthesis.Angew Chem Int Ed Engl2020
30694017Targeted Rediscovery and Biosynthesis of the Farnesyl-Transferase Inhibitor Pepticinnaminâ¿¿E.Chembiochem2019
31243997Specificity of Nonribosomal Peptide Synthetases in the Biosynthesis of the <i>Pseudomonas</i> <i>virulence factor</i>.Biochemistry2019
31247735Discovery and Biosynthesis of Azabicyclene, a Conserved Nonribosomal Peptide in Pseudomonas aeruginosa.Org Lett2019
30658055Discovery and Characterization of FMN-Binding β-Glucuronidases in the Human Gut Microbiome.J Mol Biol2019
30523678Reducing Holomycin Thiosulfonate to its Disulfide with Thiols.Chem Res Toxicol2019
29053243Identification of the Biosynthetic Pathway for the Antibiotic Bicyclomycin.Biochemistry2018
30237288Phevamine A, a small molecule that suppresses plant immune responses.Proc Natl Acad Sci U S A2018
30073838Discovery of (Dihydro)pyrazine N-Oxides via Genome Mining in Pseudomonas.Org Lett2018
30062115Gut Microbial β-Glucuronidase Inhibition via Catalytic Cycle Interception.ACS Cent Sci2018
29633497In Vitro Biosynthesis of the Nonproteinogenic Amino Acid Methoxyvinylglycine.Angew Chem Int Ed Engl2018
29382739Microbial Unmasking of Plant Glycosides.mBio2018
28032983Two Flavoenzymes Catalyze the Post-Translational Generation of 5-Chlorotryptophan and 2-Aminovinyl-Cysteine during NAI-107 Biosynthesis.ACS Chem Biol2017
28209778Role for dithiolopyrrolones in disrupting bacterial metal homeostasis.Proc Natl Acad Sci U S A2017
27355376A Chemical-Genomic Screen of Neglected Antibiotics Reveals Illicit Transport of Kasugamycin and Blasticidin S.PLoS Genet2016
26456469Direct Capture Technologies for Genomics-Guided Discovery of Natural Products.Curr Top Med Chem2016
25598489Correction: Dithiolopyrrolones: biosynthesis, synthesis, and activity of a unique class of disulfide-containing antibiotics.Nat Prod Rep2015
25650836A scalable biomimetic synthesis of resveratrol dimers and systematic evaluation of their antioxidant activities.Angew Chem Int Ed Engl2015
25726835Enzymatic basis of "hybridity" in thiomarinol biosynthesis.Angew Chem Int Ed Engl2015
24445449Antibiotic-induced shifts in the mouse gut microbiome and metabolome increase susceptibility to Clostridium difficile infection.Nat Commun2014
24835149Dithiolopyrrolones: biosynthesis, synthesis, and activity of a unique class of disulfide-containing antibiotics.Nat Prod Rep2014
23097183A backup plan for self-protection: S-methylation of holomycin biosynthetic intermediates in Streptomyces clavuligerus.Chembiochem2012
21504228Streptomyces clavuligerus HlmI is an intramolecular disulfide-forming dithiol oxidase in holomycin biosynthesis.Biochemistry2011
20351769Discovery of unique lanthionine synthetases reveals new mechanistic and evolutionary insights.PLoS Biol2010
21041678Identification of the gene cluster for the dithiolopyrrolone antibiotic holomycin in Streptomyces clavuligerus.Proc Natl Acad Sci U S A2010
20479271Catalytic promiscuity in the biosynthesis of cyclic peptide secondary metabolites in planktonic marine cyanobacteria.Proc Natl Acad Sci U S A2010
19374997Chapter 21. In vitro studies of lantibiotic biosynthesis.Methods Enzymol2009
17513866Identification of essential catalytic residues of the cyclase NisC involved in the biosynthesis of nisin.J Biol Chem2007
16527981Structure and mechanism of the lantibiotic cyclase involved in nisin biosynthesis.Science2006
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Collaborators

Matthew R Redinbo
University of North Carolina at Chapel Hill
Co-authored papers 3
Anthony L Shiver
Stanford University
Co-authored papers 2
Libusha Kelly
Albert Einstein College of Medicine
Co-authored papers 1
Athanasios Typas
University of California san francisco
Co-authored papers 1
Carol A Gross
University of California san francisco
Co-authored papers 1
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 1
Casey M Theriot
College of Veterinary Medicine, North Carolina State University
Co-authored papers 1
Neha Garg
Co-authored papers 1
Jan Claesen
Lerner Research Institute of the Cleveland Clinic
Co-authored papers 1
Vincent B Young
University of Michigan ann arbor
Co-authored papers 1
Hendrik Osadnik
University of California San Francisco
Co-authored papers 1
Douglas B Rusch
Center for Genomics and Bioinformatics, Indiana University
Co-authored papers 1
Katherine Huang
Broad Institute of MIT and Harvard
Co-authored papers 1
Jian Jin
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Co-authored papers 1
Jason M Peters
School of Pharmacy, University of Wisconsin-Madison
Co-authored papers 1
George Kritikos
Institute of Microbiology and Infection, University of Birmingham
Co-authored papers 1
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