Author details

Full Name

Alexander Kamb

Affiliation

Inc. 30301 Agoura Rd.

ORCID

Career Start Year

1979

Papers

H Index

Expertise

CM4AI Collaborator

Emma Lundberg (CM4AI)

PMID	Paper Title	Journal Title	Published Year
35235342	A carcinoembryonic antigen-specific cell therapy selectively targets tumor cells with HLA loss of heterozygosity in vitro and in vivo.	Sci Transl Med	2022
35359952	Robust <i>In Vitro</i> Pharmacology of Tmod, a Synthetic Dual-Signal Integrator for Cancer Cell Therapy.	Front Immunol	2022
35561999	The Tmod cellular logic gate as a solution for tumor-selective immunotherapy.	Clin Immunol	2022
36860694	Chimeric Antigen Receptors Directed at Mutant KRAS Exhibit an Inverse Relationship Between Functional Potency and Neoantigen Selectivity.	Cancer Res Commun	2022
36381658	HLA-Aâ¿¿02-gated safety switch for cancer therapy has exquisite specificity for its allelic target antigen.	Mol Ther Oncolytics	2022
35091455	Mesothelin-specific CAR-T cell therapy that incorporates an HLA-gated safety mechanism selectively kills tumor cells.	J Immunother Cancer	2022
35085592	A rational approach to assess off-target reactivity of a dual-signal integrator for T cell therapy.	Toxicol Appl Pharmacol	2022
33284140	Re-examination of MAGE-A3 as a T-cell Therapeutic Target.	J Immunother	2021
34432728	Potent, Selective CARs as Potential T-Cell Therapeutics for HPV-positive Cancers.	J Immunother	2021
34419823	Extensive functional comparisons between chimeric antigen receptors and T cell receptors highlight fundamental similarities.	Mol Immunol	2021
34039676	Design of TCR Structural Variants That Retain or Invert the Normal Activation Signal.	Immunohorizons	2021
33012527	Engineered T cells directed at tumors with defined allelic loss.	Mol Immunol	2020
33166305	A multivariate, quantitative assay that disentangles key kinetic parameters of primary human T cell function in vitro.	PLoS One	2020
32768859	Structure-function relationships of chimeric antigen receptors in acute T cell responses to antigen.	Mol Immunol	2020
31754147	Single variable domains from the T cell receptor Î² chain function as mono- and bifunctional CARs and TCRs.	Sci Rep	2019
26998234	Publishing confirming and non-confirming data.	F1000Res	2016
26963549	Voices of biotech.	Nat Biotechnol	2016
25487917	AMG 925 is a dual FLT3/CDK4 inhibitor with the potential to overcome FLT3 inhibitor resistance in acute myeloid leukemia.	Mol Cancer Ther	2015
26113701	SCIENTIFIC INTEGRITY. Self-correction in science at work.	Science	2015
24641103	Discovery of AMG 925, a FLT3 and CDK4 dual kinase inhibitor with preferential affinity for the activated state of FLT3.	J Med Chem	2014
24526162	Preclinical evaluation of AMG 925, a FLT3/CDK4 dual kinase inhibitor for treating acute myeloid leukemia.	Mol Cancer Ther	2014
23861887	Sphingosine kinase activity is not required for tumor cell viability.	PLoS One	2013
24213769	Human genetics as a foundation for innovative drug development.	Nat Biotechnol	2013
21630708	Next-generation sequencing and its potential impact.	Chem Res Toxicol	2011
20542731	At a crossroads in oncology.	Curr Opin Pharmacol	2010
20941365	Molecular signatures of the primitive prostate stem cell niche reveal novel mesenchymal-epithelial signaling pathways.	PLoS One	2010
19478945	Molecular signatures of prostate stem cells reveal novel signaling pathways and provide insights into prostate cancer.	PLoS One	2009
17159925	Why is cancer drug discovery so difficult?	Nat Rev Drug Discov	2007
15688078	What's wrong with our cancer models?	Nat Rev Drug Discov	2005
12857382	A high-throughput, homogeneous microplate assay for agents that kill mammalian tissue culture cells.	J Biomol Screen	2003
12890608	Functional analysis of expressed peptides that bind yeast STE proteins.	J Biotechnol	2003
12951031	Isolation of a peptide inhibitor of human rhinovirus.	Virology	2003
12949799	Overexpression of the beta-catenin binding domain of cadherin selectively kills colorectal cancer cells.	Int J Cancer	2003
14529347	Non-traditional drug targets: high risk, high reward.	Curr Gene Ther	2003
12663543	Genetic selection for modulators of a retinoic-acid-responsive reporter in human cells.	Genetics	2003
12634753	Universities could gain from backing biotech.	Nature	2003
12814603	Mutation load, functional overlap, and synthetic lethality in the evolution and treatment of cancer.	J Theor Biol	2003
12808022	Consequences of nonadaptive alterations in cancer.	Mol Biol Cell	2003
12766481	A genetic selection method for expression products that induce apoptosis in adherent mammalian cell lines.	Apoptosis	2003
11754477	Expression levels of transdominant peptides and proteins in Saccharomyces cerevisiae.	Yeast	2002
12463345	Genetic selection for modulators of the MAP kinase and beta-catenin growth-control pathways in mammalian cells.	Biochem Genet	2002
12097190	An automated system for screening retroviral expression constructs in microplate format.	J Biomol Screen	2002
12052681	Enhanced expression of exogenous genes from retroviruses using HIV2/Tat.	J Biotechnol	2002
12116372	Stable expression of Anthozoa fluorescent proteins in mammalian cells.	Cytometry	2002
11166652	Peptide inhibitors expressed in vivo.	Curr Opin Chem Biol	2001
11314269	Template selection during manipulation of complex mixtures by PCR.	Biotechniques	2001
11590620	Enrichment during transdominant genetic experiments using a flow sorter.	Cytometry	2001
11580863	Transcriptional transactivation by selected short random peptides attached to lexA-GFP fusion proteins.	BMC Mol Biol	2001
11708876	Exogenous peptide and protein expression levels using retroviral vectors in human cells.	Mol Ther	2001
11571757	Graded mode of transcriptional induction in yeast pheromone signalling revealed by single-cell analysis.	Yeast	2001

1 - 50 of 94

Kristen Jensen-Pergakes

Pfizer Inc. San Diego

Career Start Year 1998

Number of shared co-authors 0

Robert L Walker

Center for Cancer Research, National Cancer Institute, National Institutes of Health

Career Start Year 1997

Number of shared co-authors 2

Jeremy S Caldwell

Sirna Therapeutics a former subsidiary of Merck & Co., Inc.

Career Start Year 1994

Number of shared co-authors 0

David E Root

Broad Institute of Harvard and MIT

Career Start Year 1993

Number of shared co-authors 6

Abdel G Elkahloun

National Human Genome Research Institute

Career Start Year 1990

Number of shared co-authors 0

Glenn S Cowley

Broad Institute of Harvard and MIT

Career Start Year 1990

Number of shared co-authors 3

Todd R Golub

Broad Institute of MIT and Harvard

Career Start Year 1989

Number of shared co-authors 7

Eivind Hovig

Center for Bioinformatics, University of Oslo

Career Start Year 1987

Number of shared co-authors 1

Rob Hooft van Huijsduijnen

Vrije Universiteit Amsterdam (VU)

Career Start Year 1987

Number of shared co-authors 1

William C Hahn

Broad Institute of MIT and Harvard, USA Dana-Farber Cancer Institute

Career Start Year 1987

Number of shared co-authors 6

Brent W Zanke

University of Toronto

Career Start Year 1987

Number of shared co-authors 2

Timothy C Burn

Incyte Research Institute

Career Start Year 1987

Number of shared co-authors 0

Stuart L Schreiber

Broad Institute

Career Start Year 1985

Number of shared co-authors 2

Garry P Nolan

Stanford University School of Medicine

Career Start Year 1985

Number of shared co-authors 10

David D L Bowtell

Peter MacCallum Cancer Centre

Career Start Year 1983

Number of shared co-authors 2

Alan Ashworth

UCSF Helen Diller Family Comprehensive Cancer Center

Career Start Year 1982

Number of shared co-authors 8

Stephen J Elledge

Howard Hughes Medical Institute, Brigham and Women's Hospital, Harvard Medical School

Career Start Year 1982

Number of shared co-authors 0

Edison T Liu

USA The Jackson Laboratory Cancer Center

Career Start Year 1982

Number of shared co-authors 2

David J Adams

Wellcome Sanger Institute

Career Start Year 1980

Number of shared co-authors 3

Brian Seed

Center for Computational and Integrative Biology, Massachusetts General Hospital

Career Start Year 1980

Number of shared co-authors 0

Michael Dean

National Cancer Institute

Career Start Year 1980

Number of shared co-authors 6

Francisca Vazquez

Broad Institute of MIT and Harvard

Career Start Year 1979

Number of shared co-authors 4

Stephen H Friend

University of Oxford

Career Start Year 1978

Number of shared co-authors 4

Gordon B Mills

Knight Cancer Institute, Oregon Health and Sciences University

Career Start Year 1976

Number of shared co-authors 8

Louise C Showe

The Wistar Institute

Career Start Year 1975

Number of shared co-authors 1

Sean Davis

Johns Hopkins School of Medicine, National Cancer Institute, Princeton University, University of Colorado Anschutz Medical Campus, University of Pittsburgh, University of Washington

Career Start Year 1974

Number of shared co-authors 3

Raju Kucherlapati

Harvard Medical School

Career Start Year 1973

Number of shared co-authors 1

Tak W Mak

Princess Margaret Cancer Centre, University Health Network

Career Start Year 1970

Number of shared co-authors 1

John N Weinstein

The University of Texas MD Anderson Cancer Center

Career Start Year 1968

Number of shared co-authors 1

Norman E Sharpless

National Cancer Institute

Career Start Year 1945

Number of shared co-authors 0

row(s) 1 - 30 of 30

Giordano Caponigro

Co-authored papers 9

Mark A Poritz

BioFire Diagnostics Inc.

Co-authored papers 4

Michael Pierce

Co-authored papers 4

Russell Bell

Huntsman Cancer Institute at the University of Utah

Co-authored papers 3

David E Goldgar

University of Utah

Co-authored papers 2

Alun Thomas

University of Utah School of Medicine

Co-authored papers 2

Robert M Stroud

University of California San Francisco

Co-authored papers 2

Janet Finer-Moore

University of California San Francisco

Co-authored papers 2

Paola Picotti

Institute of Molecular Systems Biology, ETH Zurich

Co-authored papers 1

Kornelia Polyak

Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School

Co-authored papers 1

Barbara L Weber

Basser Center for BRCA, Abramson Cancer Center, University of Pennsylvania

Co-authored papers 1

Rabi Murad

Sanford Burnham Prebys Medical Discovery Institute

Co-authored papers 1

Frank Vollmer

Living Systems Institute, University of Exeter

Co-authored papers 1

Rune R Frants

Co-authored papers 1

Cathie Martin

John Innes Centre

Co-authored papers 1

Jackie Y Ying

Institute of Materials Research and Engineering

Co-authored papers 1

Tian Zhang

Wuhan University of Technology, PR China Shaoxing Institute for Advanced Research

Co-authored papers 1

Johanna M Rommens

The Hospital for Sick Children

Co-authored papers 1

Maria-Elena Torres-Padilla

Institute of Epigenetics and Stem Cells (IES)

Co-authored papers 1

Leena Tripathi

International Institute of Tropical Agriculture

Co-authored papers 1

Gustavo Stolovitzky

IBM T.J. Watson Research Center

Co-authored papers 1

Tuuli Lappalainen

Columbia University

Co-authored papers 1

Carolyn R Bertozzi

Stanford University

Co-authored papers 1

Sharon R Lewin

The University of Melbourne at the Peter Doherty Institute for Infection and Immunity

Co-authored papers 1

Bonnie Berger

Massachusetts Institute of Technology

Co-authored papers 1

Carl H June

University of Pennsylvania Department of Pathology & Laboratory Medicine

Co-authored papers 1

Roger A Barker

University of Cambridge

Co-authored papers 1

Jasper Rine

University of California berkeley

Co-authored papers 1

Ido Amit

Weizmann Institute of Science

Co-authored papers 1

Alessandra Biffi

Padua University and Hospital

Co-authored papers 1

1 - 30

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