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Author Details

Stuart L Schreiber
Broad Institute
1985
500
136
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37919549DNA-encoded library-enabled discovery of proximity-inducing small molecules.Nat Chem Biol2024
37919549DNA-encoded library-enabled discovery of proximity-inducing small molecules.Nat Chem Biol2024
36914634Reference compounds for characterizing cellular injury in high-content cellular morphology assays.Nat Commun2023
37816014Rational Screening for Cooperativity in Small-Molecule Inducers of Protein-Protein Associations.J Am Chem Soc2023
37582753Diversity-oriented synthesis encoded by deoxyoligonucleotides.Nat Commun2023
37909922Chemical Proteomic Discovery of Isotype-Selective Covalent Inhibitors of the RNA Methyltransferase NSUN2.Angew Chem Int Ed Engl2023
37992275Bifunctional Small Molecules That Induce Nuclear Localization and Targeted Transcriptional Regulation.J Am Chem Soc2023
37989745Author Correction: Diversity-oriented synthesis encoded by deoxyoligonucleotides.Nat Commun2023
37783940Assigning functionality to cysteines by base editing of cancer dependency genes.Nat Chem Biol2023
37084731Proteomic discovery of chemical probes that perturb protein complexes in human cells.Mol Cell2023
37024492Mapping the landscape of genetic dependencies in chordoma.Nat Commun2023
37461636Bifunctional small molecules that induce nuclear localization and targeted transcriptional regulation.bioRxiv2023
37268298Correction to "Targeted Protein Degradation by Electrophilic PROTACs that Stereoselectively and Site-Specifically Engage DCAF1".J Am Chem Soc2023
37130428Proposed Resolution of a Mechanistic Puzzle of Long Duration: Self-Condensation of Cyclopentanone to Form an 11-Carbon Dienoic Acid.J Org Chem2023
37292909Rational screening for cooperativity in small-molecule inducers of protein-protein associations.bioRxiv2023
36914634Reference compounds for characterizing cellular injury in high-content cellular morphology assays.Nat Commun2023
37909922Chemical Proteomic Discovery of Isotype-Selective Covalent Inhibitors of the RNA Methyltransferase NSUN2.Angew Chem Int Ed Engl2023
37582753Diversity-oriented synthesis encoded by deoxyoligonucleotides.Nat Commun2023
37992275Bifunctional Small Molecules That Induce Nuclear Localization and Targeted Transcriptional Regulation.J Am Chem Soc2023
37989745Author Correction: Diversity-oriented synthesis encoded by deoxyoligonucleotides.Nat Commun2023
37783940Assigning functionality to cysteines by base editing of cancer dependency genes.Nat Chem Biol2023
37816014Rational Screening for Cooperativity in Small-Molecule Inducers of Protein-Protein Associations.J Am Chem Soc2023
37024492Mapping the landscape of genetic dependencies in chordoma.Nat Commun2023
37084731Proteomic discovery of chemical probes that perturb protein complexes in human cells.Mol Cell2023
37268298Correction to "Targeted Protein Degradation by Electrophilic PROTACs that Stereoselectively and Site-Specifically Engage DCAF1".J Am Chem Soc2023
37130428Proposed Resolution of a Mechanistic Puzzle of Long Duration: Self-Condensation of Cyclopentanone to Form an 11-Carbon Dienoic Acid.J Org Chem2023
37292909Rational screening for cooperativity in small-molecule inducers of protein-protein associations.bioRxiv2023
37461636Bifunctional small molecules that induce nuclear localization and targeted transcriptional regulation.bioRxiv2023
34813762PALP: A rapid imaging technique for stratifying ferroptosis sensitivity in normal and tumor tissues in situ.Cell Chem Biol2022
35460612Inhibition of Plasmodium falciparum phenylalanine tRNA synthetase provides opportunity for antimalarial drug development.Structure2022
35395129Modular Synthesis of Cyclopropane-Fused N-Heterocycles Enabled by Underexplored Diazo Reagents.Angew Chem Int Ed Engl2022
36170674Targeted Protein Degradation by Electrophilic PROTACs that Stereoselectively and Site-Specifically Engage DCAF1.J Am Chem Soc2022
35994671Selective inhibitors of SARM1 targeting an allosteric cysteine in the autoregulatory ARM domain.Proc Natl Acad Sci U S A2022
35475490Synthesis of skeletally diverse β-lactam haptens for the <i>in vitro</i> diagnosis of IgE-mediated drug allergy.Chem Commun (Camb)2022
34965379Persister cancer cells: Iron addiction and vulnerability to ferroptosis.Mol Cell2022
35075105Bicyclic azetidines target acute and chronic stages of Toxoplasma gondii by inhibiting parasite phenylalanyl t-RNA synthetase.Nat Commun2022
34813762PALP: A rapid imaging technique for stratifying ferroptosis sensitivity in normal and tumor tissues in situ.Cell Chem Biol2022
35475490Synthesis of skeletally diverse β-lactam haptens for the <i>in vitro</i> diagnosis of IgE-mediated drug allergy.Chem Commun (Camb)2022
35395129Modular Synthesis of Cyclopropane-Fused N-Heterocycles Enabled by Underexplored Diazo Reagents.Angew Chem Int Ed Engl2022
35460612Inhibition of Plasmodium falciparum phenylalanine tRNA synthetase provides opportunity for antimalarial drug development.Structure2022
35994671Selective inhibitors of SARM1 targeting an allosteric cysteine in the autoregulatory ARM domain.Proc Natl Acad Sci U S A2022
36170674Targeted Protein Degradation by Electrophilic PROTACs that Stereoselectively and Site-Specifically Engage DCAF1.J Am Chem Soc2022
35075105Bicyclic azetidines target acute and chronic stages of Toxoplasma gondii by inhibiting parasite phenylalanyl t-RNA synthetase.Nat Commun2022
34965379Persister cancer cells: Iron addiction and vulnerability to ferroptosis.Mol Cell2022
33417864The Rise of Molecular Glues.Cell2021
34130532The Use of Informer Sets in Screening: Perspectives on an Efficient Strategy to Identify New Probes.SLAS Discov2021
33536628Author Correction: Evaluating drug targets through human loss-of-function genetic variation.Nature2021
33521702Targeted brachyury degradation disrupts a highly specific autoregulatory program controlling chordoma cell identity.Cell Rep Med2021
33559612Crystal structures of the selenoprotein glutathione peroxidase 4 in its apo form and in complex with the covalently bound inhibitor ML162.Acta Crystallogr D Struct Biol2021
33986176Cell-specific transcriptional control of mitochondrial metabolism by TIF1γ drives erythropoiesis.Science2021
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Collaborators

Broad Institute
Co-authored papers 68
Center for the Science of Therapeutics, Broad Institute
Co-authored papers 55
Co-authored papers 29
National Institute of Allergy and Infectious Diseases, National Institutes of Health
Co-authored papers 22
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Co-authored papers 22
Co-authored papers 21
Co-authored papers 21
Broad Institute of MIT and Harvard
Co-authored papers 17
Co-authored papers 17
Broad Institute of MIT and Harvard
Co-authored papers 17
Broad Institute of MIT and Harvard
Co-authored papers 17
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Co-authored papers 12
Johns Hopkins University School of Medicine
Co-authored papers 11
Broad Institute of MIT and Harvard
Co-authored papers 10
Broad Institute of Harvard and MIT
Co-authored papers 10
Broad Institute of MIT and Harvard, USA Dana-Farber Cancer Institute
Co-authored papers 9
Co-authored papers 9
Columbia University
Co-authored papers 9
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 9
Scripps Research Institute
Co-authored papers 8
Harvard Medical School, Blavatnik Institute
Co-authored papers 7
Co-authored papers 7
Harvard Medical School
Co-authored papers 7
UT Southwestern Medical Center
Co-authored papers 7
Co-authored papers 7
University of California San Diego
Co-authored papers 6
Vanderbilt-Ingram Cancer Center, Vanderbilt University
Co-authored papers 6
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 6
Broad Institute of Harvard and MIT
Co-authored papers 6
Co-authored papers 6