|
| 36370135 | Reduced synaptic proteins and SNARE complexes in Down syndrome with Alzheimer's disease and the Dp16 mouse Down syndrome model: Impact of APP gene dose. | Alzheimers Dement | 2023 |
| 38076904 | Cerebrovascular disease drives Alzheimer plasma biomarker concentrations in adults with Down syndrome. | medRxiv | 2023 |
| 37546983 | Spatial and single-nucleus transcriptomic analysis of genetic and sporadic forms of Alzheimer's Disease. | bioRxiv | 2023 |
| 37156179 | Enlarged perivascular spaces and plasma Aβ42/Aβ40 ratio in older adults without dementia. | Neurobiol Aging | 2023 |
| 37015911 | Increased plasma DYRK1A with aging may protect against neurodegenerative diseases. | Transl Psychiatry | 2023 |
| 36945447 | Plasma NT1-tau and Aβ <sub>42</sub> correlate with age and cognitive function in two large Down syndrome cohorts. | medRxiv | 2023 |
| 37382680 | Characterization of hippocampal sclerosis of aging and its association with other neuropathologic changes and cognitive deficits in the oldest-old. | Acta Neuropathol | 2023 |
| 37438872 | Plasma NT1-tau and Aβ<sub>42</sub> correlate with age and cognitive function in two large Down syndrome cohorts. | Alzheimers Dement | 2023 |
| 37035460 | Differential involvement of hippocampal subfields in the relationship between Alzheimer's pathology and memory interference in older adults. | Alzheimers Dement (Amst) | 2023 |
| 37064334 | Innovating Therapies for Down Syndrome: An International Virtual Conference of the T21 Research Society. | Mol Syndromol | 2023 |
| 36536382 | Amyloid futures in the expanding pathology of brain aging and dementia. | Alzheimers Dement | 2023 |
| 36565120 | Weight Loss and Alzheimer's Disease in Down Syndrome. | J Alzheimers Dis | 2023 |
| 36894565 | Modulating heart rate oscillation affects plasma amyloid beta and tau levels in younger and older adults. | Sci Rep | 2023 |
| 34776436 | Selective Impairment of Long-Range Default Mode Network Functional Connectivity as a Biomarker for Preclinical Alzheimer's Disease in People with Down Syndrome. | J Alzheimers Dis | 2022 |
| 35585302 | A retrotransposon storm marks clinical phenoconversion to late-onset Alzheimer's disease. | Geroscience | 2022 |
| 35705056 | Absence of microglia promotes diverse pathologies and early lethality in Alzheimer's disease mice. | Cell Rep | 2022 |
| 35472307 | Beyond amyloid: Immune, cerebrovascular, and metabolic contributions to Alzheimer disease in people with Down syndrome. | Neuron | 2022 |
| 35669316 | Obstructive sleep apnea, cerebrovascular disease, and amyloid in older adults with Down syndrome across the Alzheimer's continuum. | Sleep Adv | 2022 |
| 35634535 | Joint-label fusion brain atlases for dementia research in Down syndrome. | Alzheimers Dement (Amst) | 2022 |
| 35599543 | Commentary on Oeckl et al., "Serum Beta-Synuclein Is Higher in Down Syndrome and Precedes Rise of pTau181". | Ann Neurol | 2022 |
| 35750033 | Cholesterol and matrisome pathways dysregulated in astrocytes and microglia. | Cell | 2022 |
| 36033603 | Exploring the role of sex differences in Alzheimer's disease pathogenesis in Down syndrome. | Front Neurosci | 2022 |
| 36229634 | Blood pressure variability and plasma Alzheimer's disease biomarkers in older adults. | Sci Rep | 2022 |
| 36157622 | Primitive Reflexes and Dementia in Adults With Down Syndrome. | Neurol Clin Pract | 2022 |
| 36343257 | Aβ and tau prions feature in the neuropathogenesis of Down syndrome. | Proc Natl Acad Sci U S A | 2022 |
| 35256308 | Impact of the COVID-19 pandemic on daily life, mood, and behavior of adults with Down syndrome. | Disabil Health J | 2022 |
| 35212182 | Probing the proteome to explore potential correlates of increased Alzheimer's-related cerebrovascular disease in adults with Down syndrome. | Alzheimers Dement | 2022 |
| 35321660 | Conducting clinical trials in persons with Down syndrome: summary from the NIH INCLUDE Down syndrome clinical trials readiness working group. | J Neurodev Disord | 2022 |
| 34757693 | Impact of increased APP gene dose in Down syndrome and the Dp16 mouse model. | Alzheimers Dement | 2022 |
| 33337378 | Plasma Total-Tau and Neurofilament Light Chain as Diagnostic Biomarkers of Alzheimer's Disease Dementia and Mild Cognitive Impairment in Adults with Down Syndrome. | J Alzheimers Dis | 2021 |
| 35822024 | Neuropathology of Aging in Cats and its Similarities to Human Alzheimer's Disease. | Front Aging | 2021 |
| 33924960 | Cross-Sectional Exploration of Plasma Biomarkers of Alzheimer's Disease in Down Syndrome: Early Data from the Longitudinal Investigation for Enhancing Down Syndrome Research (LIFE-DSR) Study. | J Clin Med | 2021 |
| 34786786 | Identifying dementia in Down syndrome with the Severe Impairment Battery, Brief Praxis Test and Dementia Scale for People with Learning Disabilities. | J Intellect Disabil Res | 2021 |
| 34489686 | Postmortem Neocortical <sup>3</sup>H-PiB Binding and Levels of Unmodified and Pyroglutamate Aβ in Down Syndrome and Sporadic Alzheimer's Disease. | Front Aging Neurosci | 2021 |
| 34573150 | Cognitive and Behavioral Domains That Reliably Differentiate Normal Aging and Dementia in Down Syndrome. | Brain Sci | 2021 |
| 34687637 | Alzheimer's disease associated with Down syndrome: a genetic form of dementia. | Lancet Neurol | 2021 |
| 33969175 | Markers of early changes in cognition across cohorts of adults with Down syndrome at risk of Alzheimer's disease. | Alzheimers Dement (Amst) | 2021 |
| 34302785 | Diagnostic and prognostic performance and longitudinal changes in plasma neurofilament light chain concentrations in adults with Down syndrome: a cohort study. | Lancet Neurol | 2021 |
| 34268067 | Opportunities, barriers, and recommendations in down syndrome research. | Transl Sci Rare Dis | 2021 |
| 34239132 | Single-nucleus chromatin accessibility and transcriptomic characterization of Alzheimer's disease. | Nat Genet | 2021 |
| 33952632 | Tacrolimus Protects against Age-Associated Microstructural Changes in the Beagle Brain. | J Neurosci | 2021 |
| 34228117 | APOE ε4 Association With Cognition and Alzheimer Disease Biomarkers in Down Syndrome-Implications for Clinical Trials and Treatments for All. | JAMA Neurol | 2021 |
| 32258359 | Metabolic correlates of prevalent mild cognitive impairment and Alzheimer's disease in adults with Down syndrome. | Alzheimers Dement (Amst) | 2020 |
| 33088896 | Distribution of microglial phenotypes as a function of age and Alzheimer's disease neuropathology in the brains of people with Down syndrome. | Alzheimers Dement (Amst) | 2020 |
| 33225040 | Longitudinal assessment of dementia measures in Down syndrome. | Alzheimers Dement (Amst) | 2020 |
| 33134477 | The AT(N) framework for Alzheimer's disease in adults with Down syndrome. | Alzheimers Dement (Amst) | 2020 |
| 32944999 | Alzheimer-Related Cerebrovascular Disease in Down Syndrome. | Ann Neurol | 2020 |
| 32775597 | The Alzheimer's Biomarker Consortium-Down Syndrome: Rationale and methodology. | Alzheimers Dement (Amst) | 2020 |
| 32996650 | A preliminary study of cerebral blood flow, aging and dementia in people with Down syndrome. | J Intellect Disabil Res | 2020 |
| 32626817 | Proteomic profiles for Alzheimer's disease and mild cognitive impairment among adults with Down syndrome spanning serum and plasma: An Alzheimer's Biomarker Consortium-Down Syndrome (ABC-DS) study. | Alzheimers Dement (Amst) | 2020 |