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Author Details

Lakshmi Muthuswamy
Harvard Medical School
2005
21
16
PMIDPaper TitleJournal TitlePublished Year
36993200A Large-Scale Proteomics Resource of Circulating Extracellular Vesicles for Biomarker Discovery in Pancreatic Cancer.medRxiv2023
34789479Organoid Sensitivity Correlates with Therapeutic Response in Patients with Pancreatic Cancer.Clin Cancer Res2022
34011980Patient-derived tumor xenograft and organoid models established from resected pancreatic, duodenal and biliary cancers.Sci Rep2021
33915081Commitment and oncogene-induced plasticity of human stem cell-derived pancreatic acinar and ductal organoids.Cell Stem Cell2021
32990680PDX-derived organoids model in vivo drug response and secrete biomarkers.JCI Insight2020
27750381Molecular heterogeneity of non-small cell lung carcinoma patient-derived xenografts closely reflect their primary tumors.Int J Cancer2017
27571409RB1 deficiency in triple-negative breast cancer induces mitochondrial protein translation.J Clin Invest2016
26005866Spatial genomic heterogeneity within localized, multifocal prostate cancer.Nat Genet2015
26501191Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell- and patient-derived tumor organoids.Nat Med2015
25860294Genetic and epigenetic profiling of CLL disease progression reveals limited somatic evolution and suggests a relationship to memory-cell development.Blood Cancer J2015
24192544WaveCNV: allele-specific copy number alterations in primary tumors and xenograft models from next-generation sequencing.Bioinformatics2014
25429762Integrated omic analysis of lung cancer reveals metabolism proteome signatures with prognostic impact.Nat Commun2014
24662921Mislocalization of the cell polarity protein scribble promotes mammary tumorigenesis and is associated with basal breast cancer.Cancer Res2014
23223018Copy number variation analysis implicates the cell polarity gene glypican 5 as a human spina bifida candidate gene.Hum Mol Genet2013
23851435Integrated genomic, transcriptomic, and RNA-interference analysis of genes in somatic copy number gains in pancreatic ductal adenocarcinoma.Pancreas2013
23900255Computational approaches to identify functional genetic variants in cancer genomes.Nat Methods2013
22851698Expression profiling during mammary epithelial cell three-dimensional morphogenesis identifies PTPRO as a novel regulator of morphogenesis and ErbB2-mediated transformation.Mol Cell Biol2012
23103869Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes.Nature2012
21399628Tumour evolution inferred by single-cell sequencing.Nature2011
21969575Dosage-dependent phenotypes in models of 16p11.2 lesions found in autism.Proc Natl Acad Sci U S A2011
16869738High-resolution ROMA CGH and FISH analysis of aneuploid and diploid breast tumors.Cold Spring Harb Symp Quant Biol2005
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Collaborators

Senthil K Muthuswamy
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 7
Ming-Sound Tsao
University Health Network, University of Toronto
Co-authored papers 5
Melania Pintilie
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 4
Thomas J Hudson
Ontario Institute for Cancer Research
Co-authored papers 4
Paul C Boutros
University of California los angeles
Co-authored papers 4
John D McPherson
Ontario Institute for Cancer Research
Co-authored papers 4
Robert E Denroche
Ontario Institute for Cancer Research
Co-authored papers 3
Steven Gallinger
Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto
Co-authored papers 3
Ling Huang
Beth Israel Deaconess Medical Center, Harvard Medical School
Co-authored papers 3
Nhu-An Pham
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 3
Timothy Beck
Human Longevity Inc.
Co-authored papers 3
Dianne Chadwick
University Health Network
Co-authored papers 2
Francis Nguyen
Ontario Institute for Cancer Research
Co-authored papers 2
Christina K Yung
Ontario Institute for Cancer Research
Co-authored papers 2
Michelle Sam
Ontario Institute for Cancer Research
Co-authored papers 2
Lincoln D Stein
University of Toronto
Co-authored papers 2
Nicholas Buchner
Ontario Institute for Cancer Research
Co-authored papers 2
Thomas Kislinger
Princess Margaret Cancer Centre, University Health Network, University of Toronto
Co-authored papers 2
Andrew M K Brown
Ontario Institute for Cancer Research
Co-authored papers 2
Alexander Krasnitz
Simons Center for Quantitative Biology
Co-authored papers 2
Dennis Wang
Sheffield Institute of Translational Neuroscience, University of Sheffield
Co-authored papers 2
Maud H W Starmans
Ontario Institute for Cancer Research
Co-authored papers 2
Christine To
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
Chang-Qi Zhu
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
Frances A Shepherd
University Health Network, Princess Margaret Cancer Centre
Co-authored papers 2
James Hicks
Michelson Center for Convergent Bioscience, University of Southern California
Co-authored papers 2
Vladimir Ignatchenko
Margaret Cancer Center
Co-authored papers 2
Quang M Trinh
Ontario Institute for Cancer Research
Co-authored papers 2
Lei Li
Hospital for Sick Children
Co-authored papers 2
Niloofar Arshadi
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